Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Douglas B. Tang"'
Autor:
William F. McCarthy, Nestor Sosa, Jeanne A. Norwood, Kendra Lawrence, Ana Jiménez, Max Grogl, Janet Ransom, Charles Scott, Ryan C. Adams, Mara Kreishman-Detrick, Douglas B. Tang, Peter J. Weina, Juan Miguel Pascale
Publikováno v:
PLoS neglected tropical diseases. 13(5)
Background Paromomycin-based topical treatments were shown to be effective in curing cutaneous leishmaniasis (CL) lesions caused by Leishmania major in Tunisia. Cure rates of an index lesion were approximately 80%. As a follow on, we conducted a simi
Autor:
Darapiseth Sea, Sok Somethy, Youry Se, Satharath Prom, Chanthap Lon, Worachet Kuntawunginn, Char Meng Chour, David Saunders, Eugene Soh, Douglas B. Tang, Mark C. Haigney, Pattaraporn Vanachayangkul, Sabaithip Sriwichai, Ans Timmermans, Raveewan Siripokasupkul, Jessica E. Manning, Sut-Thang Phann, Soklyda Chann, Jaranit Kaewkungwal, Michele D. Spring, Mashamon Mitprasat, Montida Auayporn, Louis R. Cantilena, Mary So, Nillawan Buathong, Paktiya Teja-Isavadharm, Charlotte A. Lanteri
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:6056-6067
Dihydroartemisinin-piperaquine, the current first-line drug for uncomplicated malaria caused by Plasmodium falciparum and Plasmodium vivax in Cambodia, was previously shown to be of benefit as malaria chemoprophylaxis when administered as a monthly 3
Autor:
Sornchai Looareesuwan, Duangsuda Siriyanonda, Udomsak Silachamroon, D. Gray Heppner, Polrat Wilairatana, Srivicha Krudsood, Douglas S. Walsh, Thomas G. Brewer, Weerapong Phumratanaprapin, Douglas B. Tang
Publikováno v:
Clinical Infectious Diseases. 39:1095-1103
Background. Tafenoquine is an 8-aminoquinoline developed as a more effective replacement for primaquine. In a previous dose-ranging study in Thailand, 3 tafenoquine regimens with total doses ranging from 500 mg to 3000 mg prevented relapse of Plasmod
Autor:
Phongsak Jarasrumgsichol, Douglas S. Walsh, Suebpong Sangkharomy, Chainarong Cherdchu, Karl H. Rieckmann, Thomas G. Brewer, Panpaka Supakalin, Theerayuth Sasiprapha, Michael D. Edstein, Douglas B. Tang, Pradith Khaewsathien, Chirapa Eamsila
Publikováno v:
The Journal of Infectious Diseases. 190:1456-1463
We assessed monthly doses of tafenoquine for preventing Plasmodium vivax and multidrug-resistant P. falciparum malaria. In a randomized, double-blind, placebo-controlled study, 205 Thai soldiers received either a loading dose of tafenoquine 400 mg (b
Autor:
Sacared A Bodison, Robert Putnak, Douglas B. Tang, Robert R. Edelman, Bruce L. Innis, Wellington Sun, Steven S. Wasserman, Niranjan Kanesa-thasan, Kenneth H. Eckels, David W. Vaughn
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 69:48-60
Laboratory-attenuated strains of each of the four dengue serotypes previously tested as monovalent vaccines in volunteers were combined and tested for immunogenicity, safety, and reactogenicity in 16 dosage combinations. Tetravalent vaccines made usi
Autor:
Bruce L. Innis, John M. Scherer, Kenneth H. Eckels, Alan D. King, Niranjan Kanesa-thasan, Robert R. Edelman, Charles H. Hoke, Douglas B. Tang, Huo-Shu H. Houng, J. Robert Putnak, Wellington Sun
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 69:24-31
Four serotypes of monovalent live attenuated dengue virus vaccine candidates were tested for reactogenicity and immunogenicity in 49 flavivirus non-immune adult human volunteers. The four monovalent candidates were then combined into a tetravalent fo
Autor:
Colin Ohrt, Walter R. J. Taylor, Helena Picarima, Thomas L. Richie, David J. Fryauff, Trevor R. Jones, Asep Ganjar, Emiliana Tjitra, Josh Berman, Douglas B. Tang, Hasan Basri, Hendra Widjaja, Gerald S. Murphy, David J. Braitman
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:2199-2203
Drug tolerability affects compliance. We evaluated the tolerability levels of azithromycin (750-mg loading dose plus 250 mg/day; n = 148 subjects), doxycycline (100 mg/day; n = 75), and placebo ( n = 77) as prophylaxis against malaria in Indonesian a
Autor:
Douglas B. Tang, David J. Braitman, Ralf P. Brueckner, Watcharee Chokejindachai, John Horton, Thomas G. Brewer, D. Gray Heppner, Polrat Wilairatana, Parnpen Viriyavejakul, Wilbur K. Milhous, Douglas S. Walsh, Sornchai Looareesuwan, Brian G. Schuster, Dennis E. Kyle
Publikováno v:
The Journal of Infectious Diseases. 180:1282-1287
WR 238605 is an 8-aminoquinoline developed for the radical cure of Plasmodium vivax. Forty-four P. vivax-infected patients were randomly assigned to 1 of 4 treatment regimens: 3 groups received a blood schizonticidal dose of chloroquine followed by W
Autor:
G. M. Aleman, Jonathan D. Berman, M. W. Dunne, D. M. Gordon, O. B. Ragama, S. L. Andersen, G.D. Shanks, Aggrey J. Oloo, Douglas B. Tang
Publikováno v:
Clinical Infectious Diseases. 26:146-150
Azithromycin prevents malaria in animal models and early clinical trials. We determined the prophylactic efficacy of three antibiotic regimens given for 10 weeks (azithromycin, 250 mg daily; azithromycin, 1,000 mg weekly; and doxycycline, 100 mg dail
Autor:
Janet S. Foster, Wendell D. Zollinger, Douglas B. Tang, E. E. Moran, Andrew F. Trofa, Joseph J. Drabick
Publikováno v:
Vaccine. 15:1144-1148
Cimetidine (CIM) is an H2-receptor antagonist with a long history of clinical use in peptic ulcer disease. In addition to its inhibitory effect upon gastric acid secretion, CIM can also block histamine-mediated immunosuppression by inhibiting H2 rece