Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Douglas B Weibel"'
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 9, p e1005041 (2016)
Understanding how stochastic molecular fluctuations affect cell behavior requires the quantification of both behavior and protein numbers in the same cells. Here, we combine automated microscopy with in situ hydrogel polymerization to measure single-
Externí odkaz:
https://doaj.org/article/30aae8b0d5f84003a643849006f753ff
Autor:
Ratmir Derda, Jesse Gitaka, Catherine M Klapperich, Charles R Mace, Ashok A Kumar, Marya Lieberman, Jacqueline C Linnes, Joerg Jores, Johnson Nasimolo, Joseph Ndung'u, Evans Taracha, Abigail Weaver, Douglas B Weibel, Thomas M Kariuki, Paul Yager
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 5, p e0003676 (2015)
Externí odkaz:
https://doaj.org/article/92739970d70b48d59f98385a99dfd87a
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84143 (2013)
In this article we describe two techniques for exploring the relationship between bacterial cell shape and the intracellular organization of proteins. First, we created microchannels in a layer of agarose to reshape live bacterial cells and predictab
Externí odkaz:
https://doaj.org/article/40d3c5fef2884a6e9a32ef695c32cb3d
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41245 (2012)
This article describes Bacteria ID Chips ('BacChips'): an inexpensive, portable, and autonomous microfluidic platform for identifying pathogenic strains of bacteria. BacChips consist of a set of microchambers and channels molded in the elastomeric po
Externí odkaz:
https://doaj.org/article/565df6ac6fd94efa965987c428c389e1
Autor:
David M. Lynn, Ti-Yu Lin, William S. Gross, Thiago M. A. Santos, Benjamín J. Ortiz, James Jennings, Douglas B. Weibel
Publikováno v:
Chem Mater
We report the design and characterization of Fe-containing soft materials that respond to, interface with, and/or sequester Fe-chelating ‘siderophores’ that bacteria use to scavenge for iron and regulate iron homeostasis. We demonstrate that meta
Autor:
Douglas B. Weibel, Manohary Rajendram, Brandon M. Hoover, Heidi Y. Shi, Ming Zhang, Nitin Mahajan, Kiyoshi Kawasaki
Publikováno v:
The FASEB Journal. 33:6354-6364
A central question in cell biology is how cells respond to stress signals and biochemically regulate apoptosis. One critical pathway involves the change of mitochondrial function and release of cytochrome c to initiate apoptosis. In response to apopt
Publikováno v:
Cellulose. 26:2513-2528
Due to its dense nanofibril network and inadequate biocompatibility, virgin bacterial cellulose (BC) has limitations in fulfilling the complex biological requirements of cartilage tissue engineering. To address these limits, we herein demonstrate the
Autor:
Douglas B. Weibel, Fred Chang, Kerwyn Casey Huang, Lillian Zhu, George K. Auer, Amanda Miguel, Pascal D. Odermatt, Julie A. Theriot, Gabriel Billings, Enrique R. Rojas
Publikováno v:
Nature
Gram-negative bacteria possess a complex cell envelope that consists of a plasma membrane, a peptidoglycan cell wall and an outer membrane. The envelope is a selective chemical barrier1 that defines cell shape2 and allows the cell to sustain large me
Autor:
Alessandro Senes, Janice L. Robertson, Rahul Chadda, John A. Crooks, Loren M. LaPointe, Deena Al Mahbuba, Ambalika S. Khadria, Samson G.F. Condon, Aaron A. Hoskins, Gladys Diaz-Vazquez, Douglas B. Weibel, Samuel J. Craven, Qiang Cui, Claire R. Armstrong, Nambirajan Rangarajan
Publikováno v:
Journal of Biological Chemistry. 293:1623-1641
In Escherichia coli, FtsLB plays a central role in the initiation of cell division, possibly transducing a signal that will eventually lead to the activation of peptidoglycan remodeling at the forming septum. The molecular mechanisms by which FtsLB o
Autor:
Qiang Cui, Gabriel F. R. Carneiro, Maoquan Zhou, Douglas B. Weibel, Matthew G. Lammers, Dong Fang, Crystal L. Y. De Jesus, Thiago M. A. Santos, Ian L. Sparks, Madhusudan Rajendran
Publikováno v:
ACS Chemical Biology. 13:235-246
Bacterial cell division requires identification of the division site, assembly of the division machinery, and constriction of the cell envelope. These processes are regulated in response to several cellular and environmental signals. Here, we use sma