Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Douglas A. Weidner"'
Autor:
Fadi A. Issa, M. Kristen Hall, Cody J. Hatchett, Douglas A. Weidner, Alexandria C. Fiorenza, Ruth A. Schwalbe
Publikováno v:
Biology, Vol 10, Iss 6, p 486 (2021)
Neurological difficulties commonly accompany individuals suffering from congenital disorders of glycosylation, resulting from defects in the N-glycosylation pathway. Vacant N-glycosylation sites (N220 and N229) of Kv3, voltage-gated K+ channels of hi
Externí odkaz:
https://doaj.org/article/0f86af45fb914f81b2dd9c54d8c059eb
Publikováno v:
Biology, Vol 9, Iss 4, p 71 (2020)
Neuroblastoma (NB) development and progression are accompanied by changes in N-glycans attached to proteins. Here, we investigated the role of N-acetylglucosaminyltransferase-II (GnTII, MGAT2) protein substrates in neuroblastoma (NB) cells. MGAT2 was
Externí odkaz:
https://doaj.org/article/9cfbce92383242c1b6eb6584fae589b7
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 892-897 (2014)
E-cadherin is crucial for adhesion of cells to each other and thereby development and maintenance of tissue. While it is has been established that N-glycans inside the cell impact the level of E-cadherin at the cell surface of epithelial-derived cell
Externí odkaz:
https://doaj.org/article/8d61a2325b504fea85c27d68ae1aaaba
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199202 (2018)
Modifications in surface glycans attached to proteins via N-acetylglucosamine-β1-N-asparagine linkage have been linked to tumor development and progression. These modifications include complex N-glycans with high levels of branching, fucose and sial
Externí odkaz:
https://doaj.org/article/e9381eaa6afc4a0bb73036f85372db8b
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137138 (2015)
The intrinsic electrical properties of a neuron depend on expression of voltage gated potassium (Kv) channel isoforms, as well as their distribution and density in the plasma membrane. Recently, we showed that N-glycosylation site occupancy of Kv3.1b
Externí odkaz:
https://doaj.org/article/2e3af92b7ceb42baa29e5015c169d068
Publikováno v:
Chemosphere. 229:103-111
Triclosan (TCS) is a broad-spectrum antimicrobial used in personal care products, household items, and medical devices. Owing to its apoptotic potential against tumor cells, TCS has been proposed for the treatment of malignancy. A major complication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c567ae376c4daf7f2045e633328e84
https://doi.org/10.1016/j.chemosphere.2019.04.211
https://doi.org/10.1016/j.chemosphere.2019.04.211
Autor:
Douglas A. Weidner, Cody J Hatchett, Ruth A. Schwalbe, M. Kristen Hall, Alexandria C Fiorenza, Fadi A. Issa
Publikováno v:
Biology, Vol 10, Iss 486, p 486 (2021)
Biology
Volume 10
Issue 6
Biology
Volume 10
Issue 6
Simple Summary Modifications in the repertoire of N-glycans at the cell surface are associated with neurological complications. However, knowledge of specific N-glycans as to their impact on neuronal excitability is lacking. Our proposed studies will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc11b8dbc705644da7f5b8bebd93950d
https://www.mdpi.com/2079-7737/10/6/486
https://www.mdpi.com/2079-7737/10/6/486
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75013 (2013)
Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information content is unclear. This report
Externí odkaz:
https://doaj.org/article/ab07cbc54d0e4c889b160383e44c58a9
Publikováno v:
Biology
Volume 9
Issue 4
Biology, Vol 9, Iss 71, p 71 (2020)
Volume 9
Issue 4
Biology, Vol 9, Iss 71, p 71 (2020)
Neuroblastoma (NB) development and progression are accompanied by changes in N-glycans attached to proteins. Here, we investigated the role of N-acetylglucosaminyltransferase-II (GnTII, MGAT2) protein substrates in neuroblastoma (NB) cells. MGAT2 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f6e4aaf93cf457690bd2b8b1e6034f
Autor:
Joshua Daniel Stone, Douglas A. Weidner, Chintamani N Joshi, Danielle N Martin, Patti R. Shaver, Robert M. Lust, Brian M. Shewchuk, Jake T. Francisco, Shaquria P. Adderley, Andrew W. Holt, David A. Tulis
Publikováno v:
Cellular Signalling. 28:1364-1379
Coronary artery disease (CAD) accounts for over half of all cardiovascular disease-related deaths. Uncontrolled arterial smooth muscle (ASM) cell migration is a major component of CAD pathogenesis and efforts aimed at attenuating its progression are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be53a4fb8b87647c2d28c2497a20944
https://doi.org/10.1016/j.cellsig.2016.06.012
https://doi.org/10.1016/j.cellsig.2016.06.012