Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Douglas A. Treco"'
Publikováno v:
Somatic Gene Therapy ISBN: 9781351076760
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b813b915c7bf34a8bf4473350b60479f
https://doi.org/10.1201/9781351076760-4
https://doi.org/10.1201/9781351076760-4
Autor:
Katharine L. Oliver, E. Doo, Gary J. Murray, Richard F. Selden, Marianne Borowski, Jane M. Quirk, K. E. Crutchfield, Douglas A. Treco, T. J. Liang, Raphael Schiffmann, M. Myers, Neal Jeffries, Frances P. Gillespie, K. Gunter, Roscoe O. Brady, Kenneth S. Loveday, K. P. Frei, M. Sellos-Moura, Constance Kreps, T. Anderson, Gregory C. Zirzow, Peter Francis Daniel
Publikováno v:
Proceedings of the National Academy of Sciences. 97:365-370
Fabry disease is a lysosomal storage disorder caused by a deficiency of the lysosomal enzyme α-galactosidase A (α-gal A). This enzymatic defect results in the accumulation of the glycosphingolipid globotriaosylceramide (Gb 3 ; also referred to as c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b348590aedfb1f0a50e388510e413f
https://doi.org/10.1073/pnas.97.1.365
https://doi.org/10.1073/pnas.97.1.365
Autor:
Richard F. Selden, Douglas A. Treco
Publikováno v:
Molecular Medicine Today. 1:314-321
Gene therapy is a medical/surgical intervention currently being developed, in which genes are introduced into cells in order to treat or cure a wide variety of human diseases. The field has evolved over the past four decades, with most experimental g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caef68d802f765632999ecfb638d6875
https://doi.org/10.1016/s1357-4310(95)80030-1
https://doi.org/10.1016/s1357-4310(95)80030-1
Autor:
Antoinette M. Zuliani, Michael W. Heartlein, Victoria A. Roman, Richard F. Selden, Douglas A. Treco, Ji-Lei Jiang, Joan W. Sellers
Publikováno v:
Proceedings of the National Academy of Sciences. 91:10967-10971
The application of somatic cell gene therapy to large patient populations will require the development of safe and practical approaches to the generation and characterization of genetically manipulated cells. Transkaryotic implantation is a gene ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e912d8c77ae0589e2fd71df3b14727b9
https://doi.org/10.1073/pnas.91.23.10967
https://doi.org/10.1073/pnas.91.23.10967
Autor:
Kevin Leu, Jack W. Szostak, Tibor Antal, Irene A. Chen, Martin A. Nowak, Sudha Rajamani, Justin K. Ichida, Douglas A. Treco
Publikováno v:
Journal of the American Chemical Society, vol 132, iss 16
Journal of the American Chemical Society
Journal of the American Chemical Society
The frequency of errors during genome replication limits the amount of functionally important information that can be passed on from generation to generation. During the origin of life, mutation rates are thought to have been quite high, raising a cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f55a566b59e07f2e61e117412704d60
https://escholarship.org/uc/item/5pr3320q
https://escholarship.org/uc/item/5pr3320q
Autor:
Douglas A. Treco, Fred Winston
Publikováno v:
Current Protocols in Molecular Biology
Yeast cultures can be grown, maintained, and stored in liquid media or on agar plates using techniques similar to those for bacterial cultures. This unit describes culture conditions for these basic techniques. Additional methods describe determinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ec1e57e2a21778232b216d0317ffe5
https://pubmed.ncbi.nlm.nih.gov/18265098
https://pubmed.ncbi.nlm.nih.gov/18265098
Autor:
Douglas A. Treco, Victoria Lundblad
Publikováno v:
Current Protocols in Molecular Biology
Preparation of sterile media of consistently high quality is essential for the genetic manipulation of yeast. Recipes for media needed in the protocols in this chapter are provided in this unit. Specific suppliers are recommended for specific ingredi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366d7e631b96f214d1a81333bf78e9e7
https://pubmed.ncbi.nlm.nih.gov/18265093
https://pubmed.ncbi.nlm.nih.gov/18265093
Autor:
Sheref S. Mansy, Douglas A. Treco, Jack W. Szostak, Mathangi Krishnamurthy, Sylvia Tobe, Jason P. Schrum
Publikováno v:
Nature. 454(7200)
The phospholipids that form the membranes of modern cells present a formidable barrier to polar and charged molecules, necessitating complex channels and pumps to permit the exchange of molecules with the external environment. This presents a problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb14ecaaf77cd884599159fbd138be2
https://pubmed.ncbi.nlm.nih.gov/18596792
https://pubmed.ncbi.nlm.nih.gov/18596792
Autor:
Douglas A. Treco, Dhamnaskar Ketki Ashok, Kathleen Seyb, Demarco Steven James, Vaishnavi Rajagopal, Michelle Denise Arata, Masha Fridkis-Hareli, Guo-Qing Tang, Hammer Robert Paul, Alonso Ricardo, Sylvia Tobe
Publikováno v:
Blood. 126:939-939
Regulation of the terminal phase of the complement component pathway is a clinically validated approach for the therapeutic treatment of complement disorders. Inhibition of complement activation at the C5 level with the monoclonal antibody eculizumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1a6558f3c22d74c96a694c42bad48f0
https://doi.org/10.1182/blood.v126.23.939.939
https://doi.org/10.1182/blood.v126.23.939.939
Autor:
Dhamnaskar Ketki Ashok, Hammer Robert Paul, Hong Zheng, Zhaolin Wang, Sylvia Tobe, Kristopher Josephson, Douglas A. Treco, Michelle Denise Arata, Alonso Ricardo, Demarco Steven James, Kathleen Seyb
Publikováno v:
Blood. 124:2936-2936
The involvement of complement in the pathogenesis of serious, life-threatening diseases underscores the importance in developing therapeutics to intervene in this cascade. Specifically, dysregulation of the complement system is central in multiple he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22e4e7c8a403b703d9aeac28dd509e53
https://doi.org/10.1182/blood.v124.21.2936.2936
https://doi.org/10.1182/blood.v124.21.2936.2936