Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Douglas A. Pippin"'
Autor:
Benjamin E. Blass, Kevin M. Blattner, John C. Gordon, Khaled M. Elokely, Douglas A. Pippin, Daniel J. Canney
Publikováno v:
Medicinal Chemistry Research. 31:1209-1223
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8309e8bf80f690773e6cd72a06cb6168
https://doi.org/10.1007/s00044-022-02909-8
https://doi.org/10.1007/s00044-022-02909-8
Publikováno v:
ACS chemical neuroscience. 10(1)
It is well-documented that serotonin (5-HT) exerts its pharmacological effects through a series of 5-HT receptors. The most recently identified member of this family, 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6c2f23329ac2cdb0cf8565d494ba401
https://pubmed.ncbi.nlm.nih.gov/30020772
https://pubmed.ncbi.nlm.nih.gov/30020772
Autor:
Douglas J. Pippin
Publikováno v:
British Forts and Their Communities
British policy in the American Colonies—leading up to the Revolutionary War—restricted colonial expansion and discouraged settlement on the frontier. When that war broke out, maintaining control of the Great Lakes region was complicated by the la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad224cf2496b89605fafdc14e943c63
https://doi.org/10.2307/j.ctvx0756k.9
https://doi.org/10.2307/j.ctvx0756k.9
Publikováno v:
Journal of Medicinal Chemistry. 51:5149-5171
toward kinase inhibitor discovery, with the result that several kinase inhibitors have been approved as drugs since 2001. The commercial success of imatinib (N-(4-methyl-3-(4-(pyridin-3yl)pyrimidin-2-ylamino)phenyl)-4-((4-methylpiperazin-1-l)methyl)b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfdacb02a80ba9f72c931b97abe0190
https://doi.org/10.1021/jm800475y
https://doi.org/10.1021/jm800475y
Autor:
Jiasheng Guo, Douglas F. Fry, Sundaramoorthi Rajeswari, Guolin Cai, Imad M. Adel Odeh, Sam H. Leung, Subhas C. Buddhu, Douglas A. Pippin, Sheila I. Hauck, Indranath Ghosh, Peter A. Jacobi, Lisa D. Coutts, Wanjun Zheng, Robert Desimone
Publikováno v:
Synlett. 2005:2861-2885
An account is given of the author's several approaches to the synthesis of the parent chromophore of phytochrome (1), a protein-bound linear tetrapyrrole derivative that controls photomorphogenesis in higher plants. These studies culminated in enanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5b91d944525915b3322512e49cf3e0
https://doi.org/10.1055/s-2005-918956
https://doi.org/10.1055/s-2005-918956
Autor:
James W. Darrow, Aaron Bourret, Robert Desimone, Jin-Ming Xiong, Patricia Maciejewski, Seung H. Lee, David C. Eustice, Mihaela Diana Danca, Douglas A. Pippin, David R. Brittelli, Kropf Jeffrey E, Peter Blomgren, Melissa Hill-Drzewi, Kevin S. Currie, Lisa Elkin, Steven L. Gallion, Scott A. Mitchell
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(24)
Inhibition of receptor tyrosine kinases (RTKs) such as vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs) has been validated by recently launched small molecules Sutent® and Nexavar®, both of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7202d556fa080f4e12292f4943f66c5
https://pubmed.ncbi.nlm.nih.gov/19879134
https://pubmed.ncbi.nlm.nih.gov/19879134
Publikováno v:
ChemInform. 39
toward kinase inhibitor discovery, with the result that several kinase inhibitors have been approved as drugs since 2001. The commercial success of imatinib (N-(4-methyl-3-(4-(pyridin-3yl)pyrimidin-2-ylamino)phenyl)-4-((4-methylpiperazin-1-l)methyl)b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7259ef73433538f3d0a4e33a7e5d96ff
https://doi.org/10.1002/chin.200850260
https://doi.org/10.1002/chin.200850260
Publikováno v:
Journal of Medicinal Chemistry; Jul2008, Vol. 51 Issue 17, p5149-5171, 23p