Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Douglas A. Monks"'
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-21 (2022)
Highlights 1. Adaptations in bone, lean, and total mass after forced endurance exercise are sex-dependent in rats. 2. Sex differences in muscle fiber-type size and proportion, lean body mass, and bone density are independent of exercise in rats. 3. M
Externí odkaz:
https://doaj.org/article/c1eb6dd7a4d04150a8f322e8122b0225
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118120 (2015)
Kennedy's disease/Spinobulbar muscular atrophy (KD/SBMA) is a degenerative neuromuscular disease affecting males. This disease is caused by polyglutamine expansion mutations of the androgen receptor (AR) gene. Although KD/SBMA has been traditionally
Externí odkaz:
https://doaj.org/article/6c12533de3d74f47aa5d2c1051292357
Publikováno v:
Behavioural brain research. 391
Sexual attraction is robustly sexually differentiated among mammalian species. Gonadal androgens acting perinatally and in adulthood are required for male-typical preference for female sexual cues. Recent evidence suggests that at the high extent of
Autor:
Angus P. Yu, Helen K. W. Law, Sally C. Y. Wong, Christopher Lai, Bjorn T. Tam, Benjamin Y. Yung, Parco M. Siu, Douglas A. Monks, Eric W C Tam, Xu P. Wang, Felix N. Ugwu, Shea Ping Yip, Rashmi Supriya, Pin Ouyang, Lawrence W. C. Chan, Su P. Koh, Thomas K. Sin, Xiao M. Pei
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Pressure-induced injury (PI), such as a pressure ulcer, in patients with limited mobility is a healthcare issue worldwide. PI is an injury to skin and its underlying tissue such as skeletal muscle. Muscle compression, composed of mechanical deformati
Publikováno v:
Hormones and Behavior. 83:14-22
In mice, male-typical preference for female olfactory cues results largely from sexually differentiated testosterone production. It is currently unclear on which cells and tissues testosterone acts to produce male-typical preference for female olfact
Autor:
M. Ibrahim, Dwayne K. Hamson, Douglas A. Monks, Ashlyn Swift-Gallant, Liisa A.M. Galea, Paula Duarte-Guterman
Publikováno v:
Journal of neuroendocrinology. 30(4)
Adult hippocampal neurogenesis occurs in many mammalian species. In rats, the survival of new neurones within the hippocampus is modulated by the action of androgen via the androgen receptor (AR); however, it is not known whether this holds true in m
Autor:
Ashlyn Swift-Gallant, Douglas A. Monks
Publikováno v:
Journal of neuroendocrinology. 30(2)
Although gonadal testosterone is the principal endocrine factor that promotes masculine traits in mammals, the development of a male phenotype requires local production of both androgenic and oestrogenic signals within target tissues. Much of our kno
Autor:
Ashlyn Swift-Gallant, Douglas A. Monks
Publikováno v:
Frontiers in neuroendocrinology. 46
Testicular androgens are the major endocrine factor promoting masculine phenotypes in vertebrates, but androgen signaling is complex and operates via multiple signaling pathways and sites of action. Recently, selective androgen receptor mutants have
Autor:
T. Brkic, Ashlyn Swift-Gallant, Douglas A. Monks, Firyal Ramzan, Lindsay A. Coome, L. Melhuish Beaupre
Publikováno v:
Journal of neuroendocrinology. 29(9)
The spinal nucleus of the bulbocavernosus (SNB) is a sexually dimorphic neuromuscular system in which the masculinisation of cell number is assumed to depend on the action of perinatal androgen in non-neural targets, whereas the masculinisation of ce
Publikováno v:
Developmental Neurobiology. 68:115-122
The bulbocavernosus (BC) and levator ani (LA) muscles of rats show remarkable androgen-dependent sexual dimorphism. These muscles are additionally of interest because they are thought to indirectly mediate sexual differentiation of innervating spinal