Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Douglas A. Formolo"'
Autor:
Douglas A. Formolo, Jiasui Yu, Kangguang Lin, Hector W. H. Tsang, Haining Ou, Georg S. Kranz, Suk-Yu Yau
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-18 (2023)
Abstract Understanding and treating Alzheimer’s disease (AD) has been a remarkable challenge for both scientists and physicians. Although the amyloid-beta and tau protein hypothesis have largely explained the key pathological features of the diseas
Externí odkaz:
https://doaj.org/article/ebbdab6236dc4b8381a231e3ac9dabed
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Depression and anxiety are devastating disorders. Understanding the mechanisms that underlie the development of depression and anxiety can provide new hints on novel treatments and preventive strategies. Here, we summarize the latest findings reporti
Externí odkaz:
https://doaj.org/article/0ccf213457644f0ea724daa48cfb191c
Autor:
Douglas A. Formolo, Thomas H. Lee, Jiasui Yu, Kangguang Lin, Gang Chen, Georg S. Kranz, Suk-Yu Yau
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 249 (2023)
(1) Background: Adiponectin is an adipocyte-secreted hormone that has antidepressant- and anxiolytic-like effects in preclinical studies. Here, we investigated the antidepressant- and anxiolytic-like effects of sub-chronic treatment with AdipoRon, an
Externí odkaz:
https://doaj.org/article/a4ab0ab91a3b4d73bbe53641fd545344
Autor:
Douglas A. Formolo, Joana M. Gaspar, Hiago M. Melo, Tuany Eichwald, Ramiro Javier Zepeda, Alexandra Latini, Michael S. Okun, Roger Walz
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
The global prevalence of obesity has been steadily increasing. Although pharmacotherapy and bariatric surgeries can be useful adjuvants in the treatment of morbid obesity, they may lose long-term effectiveness. Obesity result largely from unbalanced
Externí odkaz:
https://doaj.org/article/7dc0042e30fb4e7998b920979f16bf81
Autor:
Suk-Yu Yau, Thomas Ho-Yin Lee, Douglas Affonso Formolo, Wing-Lun Lee, Leo Chun-Kit Li, Parco M. Siu, Chetwyn C. H. Chan
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Research suggests that maternal exercise in pregnancy may have beneficial effects on the brain function of offspring. This study sought to determine if voluntary wheel running during pregnancy improves depression-like behavior, temporal order memory,
Externí odkaz:
https://doaj.org/article/a00f822da2d847ce9c1ebb54e115cf81
Autor:
Thomas H. Lee, Malegaddi Devaki, Douglas A. Formolo, Julia M. Rosa, Andy S. K. Cheng, Suk-Yu Yau
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 20; Issue 7; Pages: 5371
Chemotherapy-induced cognitive impairment (chemobrain) and muscle wasting (cachexia) are persisting side effects which adversely affect the quality of life of cancer survivors. We therefore investigated the efficacy of physical exercise as a non-phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bca30e50fd5ee40d9e0eb602d4c5ae1
Publikováno v:
Brain plasticity (Amsterdam, Netherlands). 8(1)
Brain plasticity and metabolism are tightly connected by a constant influx of peripheral glucose to the central nervous system in order to meet the high metabolic demands imposed by neuronal activity. Metabolic disturbances highly affect neuronal pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e5ec3313199bfeac5dc70da39851f3
https://pubmed.ncbi.nlm.nih.gov/36448043
https://pubmed.ncbi.nlm.nih.gov/36448043
Publikováno v:
Frontiers in Behavioral Neuroscience
Frontiers in Behavioral Neuroscience, Frontiers, 2022, 16, ⟨10.3389/fnbeh.2022.828258⟩
Frontiers in Behavioral Neuroscience, Frontiers, 2022, 16, ⟨10.3389/fnbeh.2022.828258⟩
International audience; Depression and anxiety are devastating disorders. Understanding the mechanisms that underlie the development of depression and anxiety can provide new hints on novel treatments and preventive strategies. Here, we summarize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7eadb6c8a275c1ef195cc27c054d21e
https://pubmed.ncbi.nlm.nih.gov/35299696
https://pubmed.ncbi.nlm.nih.gov/35299696
Publikováno v:
Molecular Neurobiology
Depression is the most devastating mental disorder and one of the leading contributors to the global medical burden. Current antidepressant prescriptions present drawbacks, including treatment resistance, delayed onset of treatment response, and side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959fcbcc39b049ea458b76c5053361ba
https://doi.org/10.1007/s12035-019-01644-3
https://doi.org/10.1007/s12035-019-01644-3
Autor:
Alexandre Ademar Hoeller, Cristiane Ribeiro de Carvalho, Pedro Leite Costa Franco, Douglas Affonso Formolo, Alexandre Kracker Imthon, Henrique Rodighero dos Santos, Ingrid Eidt, Gabriel Roman Souza, Leandra Celso Constantino, Camila Leite Ferreira, Rui Daniel Prediger, Rodrigo Bainy Leal, Roger Walz
Publikováno v:
Pharmaceuticals, Vol 10, Iss 3, p 75 (2017)
(1) Objectives: Epilepsy disorder is likely to increase with aging, leading to an increased incidence of comorbidities and mortality. In spite of that, there is a lack of information regarding this issue and little knowledge of cognitive and emotiona
Externí odkaz:
https://doaj.org/article/8746d3de2ded45a4895a331845e8390c