Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Douglas A. Carlow"'
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205685 (2018)
P-selectin expressed on activated endothelia and platelets supports recruitment of leukocytes expressing P-selectin ligand to sites of inflammation. While monitoring P-selectin ligand expression on activated CD8+ T cells in murine adoptive transfer m
Externí odkaz:
https://doaj.org/article/a6dd3e7f0a9949d3a4a235866e573298
Publikováno v:
Vaccine. 40(10)
Adjuvant activity of the Toll receptor 9 agonist CpG 1826 was compared when given subcutaneously (s.c.) together with ovalbumin (s.c.[CpG + Ova]), or when given by either s.c. or intradermally (i.d.) routes two days prior to s.c. ovalbumin. Frequenci
Autor:
Jan P. Dutz, Jacqueline C.Y. Lai, Douglas A. Carlow, Wing Ki Cheng, Patrick D Hopkins, Mitsuhiro Komba
Publikováno v:
The Journal of Immunology. 203:2443-2450
Skin tissue resident memory T cells (TRM) provide superior protection to a second infection. In this study, we evaluated the use of topical CpG oligodeoxynucleotide (ODN) as adjuvant to generate skin TRM in mice. Topical or s.c. CpG ODN adjuvant admi
Autor:
Hermann J. Ziltener, Abdalla Sheikh, Ninan Abraham, Adam W. Plumb, Douglas A. Carlow, Daniel T. Patton
Publikováno v:
Immunology & Cell Biology. 95:916-924
Interleukin-7 (IL-7) is essential for the development of T cells in humans and mice where deficiencies in IL-7 signaling result in severe immunodeficiency. T cells require IL-7 at multiple points during development; however, it is unclear when IL-7 i
One sentence summaryMurine primary in-vivo activated CD8+ T cells express two ligands for P-selectin, canonical PSGL-1 and a cell-extrinsic ligand docked on L-selectin.AbstractP-selectin (PSel) expressed on activated endothelia and platelets supports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13afa81301c6e8d42e33e3780aed715
Autor:
Krystle M. Veerman, Douglas A. Carlow, Marc S. Horwitz, Iryna Shanina, John J. Priatel, Hermann J. Ziltener
Publikováno v:
The Journal of Immunology. 188:1638-1646
P-selectin glycoprotein ligand-1 (PSGL-1), a heavily glycosylated sialomucin expressed on most leukocytes, has dual function as a selectin ligand for leukocyte rolling on vascular selectins expressed in inflammation and as a facilitator of resting T
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205685 (2018)
PLoS ONE
PLoS ONE
P-selectin expressed on activated endothelia and platelets supports recruitment of leukocytes expressing P-selectin ligand to sites of inflammation. While monitoring P-selectin ligand expression on activated CD8+ T cells in murine adoptive transfer m
Autor:
Klaus Gossens, Wooseok Seo, Silvia Naus, Krystle M. Veerman, Douglas A. Carlow, Hermann J. Ziltener
Publikováno v:
Immunological Reviews. 230:75-96
The substantial importance of P-selectin glycoprotein ligand 1 (PSGL-1) in leukocyte trafficking has continued to emerge beyond its initial identification as a selectin ligand. PSGL-1 seemed to be a relatively simple molecule with an extracellular mu
Autor:
Douglas A. Carlow, Hermann J. Ziltener
Publikováno v:
The Journal of Immunology. 177:6450-6459
Using noncompetitive methodologies comparing CD43+/+ and CD43−/− mice, it has been reported that CD43−/− leukocytes exhibit reduced recruitment efficiency to sites of inflammation. More recent analyses demonstrate that CD43 on activated T cel
Publikováno v:
The Journal of Immunology. 171:5100-5106
Thymic negative selection and contraction of responding T cell oligoclones after infection represent important cell ablation processes required for maintaining T cell homeostasis. It has been proposed that galectin 1 contributes to these processes th