Výsledky vyhledávání - "Douglas A. Brook"

Akademický článek

Reinterpretation of prostate cancer pathology by Appl1, Sortilin and Syndecan-1 biomarkers

Publikováno v: Scientific Data, Vol 11, Iss 1, Pp 1-10 (2024)

Abstract The diagnosis of prostate cancer using histopathology is reliant on the accurate interpretation of prostate tissue sections. Current standards rely on the assessment of Haematoxylin and Eosin (H&E) staining, which can be difficult to interpr

Externí odkaz: https://doaj.org/article/7812ab7abe164dde80c9cc732a6b3935

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Akademický článek

Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)

Abstract Prostate cancer (PCa) development and progression relies on the programming of glucose and lipid metabolism, and this involves alterations in androgen receptor expression and signalling. Defining the molecular mechanism that underpins this m

Externí odkaz: https://doaj.org/article/50253ef611194e4595e03d647adf9305

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Akademický článek

Plasminogen activator inhibitor 1 is associated with high-grade serous ovarian cancer metastasis and is reduced in patients who have received neoadjuvant chemotherapy

Autor: Tanya E. Kelly, Cathy L. Spillane, Mark P. Ward, Karsten Hokamp, Yanmei Huang, Prerna Tewari, Cara M. Martin, Lucy A. Norris, Bashir M. Mohamed, Mark Bates, Robert Brooks, Stavros Selemidis, Douglas A. Brooks, Waseem Kamran, Feras Abu Saadeh, Sharon A. O’Toole, John J. O’Leary

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Introduction: High-grade serous ovarian cancer (HGSOC) is the most prevalent and deadliest subtype of epithelial ovarian cancer (EOC), killing over 140,000 people annually. Morbidity and mortality are compounded by a lack of screening methods, and re

Externí odkaz: https://doaj.org/article/33bd691aaea5495980163d42d2344d28

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Audited financial statements in the us federal government: The question of policy and management utility

Autor: Douglas A. Brook

Publikováno v: Journal of Public Budgeting, Accounting & Financial Management. 25:135-157

The Chief Financial Officers Act and subsequent legislation require federal agencies to produce corporate-style financial statements. Arguments for financial statements drew on private sector analogies and suggested policy makers and managers would u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19318309b4cabdbaab12d1b8b4685843
https://doi.org/10.1108/jpbafm-25-01-2013-b007

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Akademický článek

Altered endosomal-lysosomal biogenesis in melanoma

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 43, Iss , Pp 100924- (2023)

Cutaneous melanoma is the deadliest form of skin neoplasm and its high mortality rates could be averted by early accurate detection. While the detection of melanoma is currently reliant upon melanin visualisation, research into melanosome biogenesis,

Externí odkaz: https://doaj.org/article/435cd90a96ca43a8a4ec2ccb6dc3f658

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Budgeting for national security: A whole of government perspective

Autor: Douglas A. Brook

Publikováno v: Journal of Public Budgeting, Accounting & Financial Management. 24:32-57

There is a current argument that “national security” and “national defense” are no longer synonymous terms-that there is a new and broader definition for the activities that contribute to “the common defense.“ A whole of government approa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb13c5e90031befe825fc8af8578bef7
https://doi.org/10.1108/jpbafm-24-01-2012-b002

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