Zobrazeno 1 - 10
of 845
pro vyhledávání: '"Douglas A, Young"'
Autor:
Rachel P. J. Lai, Teresa Cortes, Suzaan Marais, Neesha Rockwood, Melissa L. Burke, Acely Garza-Garcia, Stuart Horswell, Abdul K. Sesay, Anne O’Garra, Douglas B. Young, Robert J. Wilkinson
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT The crucial transmission phase of tuberculosis (TB) relies on infectious sputum and yet cannot easily be modeled. We applied one-step RNA sequencing (RNA-Seq) to sputum from infectious TB patients to investigate the host and microbial enviro
Externí odkaz:
https://doaj.org/article/a2bdaa3205d34c598027e743e90391af
Autor:
Alexander C. Williard, Hannah J. Switzer, Christina A. Howard, Rui Yin, Brent L. Russell, Ritwik Sanyal, Shaun Yu, Trinity M. Myers, Brian M. Flood, Oliver Kerscher, Douglas D. Young
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2826 (2022)
Protein modification with non-canonical amino acids (ncAAs) represents a useful technology to afford homogenous samples of bioconjugates with site-specific modification. This technique can be directly applied to the detection of aberrant SUMOylation
Externí odkaz:
https://doaj.org/article/fdeb925ff51f4b61b7dff9b3e8228671
Autor:
Álvaro Chiner-Oms, Michael Berney, Christine Boinett, Fernando González-Candelas, Douglas B. Young, Sebastien Gagneux, William R. Jacobs, Julian Parkhill, Teresa Cortes, Iñaki Comas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
A variety of biological differences exist between strains and phylogenetic lineages in the Mycobacterium tuberculosis complex (MTBC). Here, the authors perform RNAseq and methylome analysis of the main clades of the MTBC and show variation in transcr
Externí odkaz:
https://doaj.org/article/420da98a568148859292e03efed69a7b
Autor:
Lauren Pilcher, Sarah Pahlke, Olivia Urquhart, Kelly K. O’Brien, Vineet Dhar, Margherita Fontana, Carlos González-Cabezas, Martha Ann Keels, Ana Karina Mascarenhas, Marcelle M. Nascimento, Jeffrey A. Platt, Gregory J. Sabino, Rebecca L. Slayton, Norman Tinanoff, Douglas A. Young, Domenick T. Zero, Malavika P. Tampi, DeVonna Purnell, Josefina Salazar, Spiro Megremis, Diane Bienek, Alonso Carrasco-Labra
Publikováno v:
The Journal of the American Dental Association. 154:e1-e98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc5767d62604e62335266e41fb19a108
https://doi.org/10.1016/j.adaj.2022.09.012
https://doi.org/10.1016/j.adaj.2022.09.012
Autor:
Hannah J. Switzer, Christina A. Howard, John F. Halonski, Emily M. Peairs, Nolan Smith, Maddy P. Zamecnik, Sanjana Verma, Douglas D. Young
Publikováno v:
RSC Advances. 13:8496-8501
A carboxylesterase derived from Sulfolobus solfataricus P1 was immobilized onto an epoxy-activated Sepharose resin via non-canonical amino acids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dce0cec7983ba76043f31f8af7ae01e
https://doi.org/10.1039/d3ra00392b
https://doi.org/10.1039/d3ra00392b
Autor:
Douglas T. Young
Publikováno v:
The Physics Teacher. 61:31-33
Experiments involving RC circuits are an integral part of introductory physics courses. Previous articles using RC circuits describe determining the charge on a Van de Graaff generator, measuring currents and voltages in a charging RC circuit using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::306c5edf82a37f726722601146750b15
https://doi.org/10.1119/5.0077442
https://doi.org/10.1119/5.0077442
Autor:
Elizabeth A. King, Emily M. Peairs, Diya M. Uthappa, Jordan K. Villa, Cameron M. Goff, Naya K. Burrow, Rebecca T. Deitch, Anna K. Martin, Douglas D. Young
Publikováno v:
Molecules, Vol 26, Iss 16, p 5072 (2021)
Protein methyltransferases are vital to the epigenetic modification of gene expression. Thus, obtaining a better understanding of and control over the regulation of these crucial proteins has significant implications for the study and treatment of nu
Externí odkaz:
https://doaj.org/article/ab4433e255a849f19e3efa5b89a935f3
Autor:
Teresa Cortes, Olga T. Schubert, Amir Banaei-Esfahani, Ben C. Collins, Ruedi Aebersold, Douglas B. Young
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Mycobacterium tuberculosis has succeeded as a human pathogen for tens of thousands of years thanks to its ability to resist and adapt to the adverse conditions it encounters upon infection. Bacterial adaptation to stress is commonly viewed i
Externí odkaz:
https://doaj.org/article/6c777e17ef37415aa7763f9a16e8e9b1
Autor:
Elena Hailu, Daire Cantillon, Carlos Madrazo, Graham Rose, Paul R. Wheeler, Paul Golby, Bethlehem Adnew, Sebastien Gagneux, Abraham Aseffa, Stephen V. Gordon, Iñaki Comas, Douglas B. Young, Simon J. Waddell, Gerald Larrouy-Maumus, Stefan Berg
Publikováno v:
Microbial Genomics. 9
16 páginas, 6 figuras, 2 tablas
Lineage 7 (L7) emerged in the phylogeny of the Mycobacterium tuberculosis complex (MTBC) subsequent to the branching of 'ancient' lineage 1 and prior to the Eurasian dispersal of 'modern' lineages 2, 3 and 4. In
Lineage 7 (L7) emerged in the phylogeny of the Mycobacterium tuberculosis complex (MTBC) subsequent to the branching of 'ancient' lineage 1 and prior to the Eurasian dispersal of 'modern' lineages 2, 3 and 4. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6838ac86838923edd63a0a14bb73a2d
https://doi.org/10.1099/mgen.0.001011
https://doi.org/10.1099/mgen.0.001011
Autor:
Jeremy Horst Keeper, Laura J. Kibbe, Madhuli Thakkar-Samtani, Lisa J. Heaton, Courtney Desrosiers, Kathryn Vela, Bennett T. Amaechi, Anahita Jablonski-Momeni, Douglas A. Young, Jeanette MacLean, Robert J. Weyant, Andrea Ferreira Zandona, Woosung Sohn, Nigel Pitts, Julie Frantsve-Hawley
Publikováno v:
The Journal of the American Dental Association.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b65d3c7bd9b45702eda78d98bd3d876
https://doi.org/10.1016/j.adaj.2023.03.014
https://doi.org/10.1016/j.adaj.2023.03.014