Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Douglas A, Nitz"'
Autor:
Lujia Chen, Xiaoxiao Lin, Qiao Ye, Zoran Nenadic, Todd C. Holmes, Douglas A. Nitz, Xiangmin Xu
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106703- (2023)
Summary: Hippocampal CA1 neuronal ensembles generate sequential patterns of firing activity that contribute to episodic memory formation and spatial cognition. Here we used in vivo calcium imaging to record neural ensemble activities in mouse hippoca
Externí odkaz:
https://doaj.org/article/9d92c0cd42944b678ccdd98f426621bd
Autor:
Hai Zhang, Lujia Chen, Kevin G. Johnston, Joshua Crapser, Kim N. Green, Nicole My-Linh Ha, Andrea J. Tenner, Todd C. Holmes, Douglas A. Nitz, Xiangmin Xu
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105939- (2023)
A key challenge in developing diagnosis and treatments for Alzheimer's disease (AD) is to detect abnormal network activity at as early a stage as possible. To date, behavioral and neurophysiological investigations in AD model mice have yet to conduct
Externí odkaz:
https://doaj.org/article/94f303bca8164062b3c45e8aa6ad71c0
Autor:
Andrew S. Alexander, Janet C. Tung, G. William Chapman, Allison M. Conner, Laura E. Shelley, Michael E. Hasselmo, Douglas A. Nitz
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110504- (2022)
Summary: Rats readily switch between foraging and more complex navigational behaviors such as pursuit of other rats or prey. These tasks require vastly different tracking of multiple behaviorally significant variables including self-motion state. To
Externí odkaz:
https://doaj.org/article/ed72df8d89a9473aa8267593cbb4ebf6
Autor:
Xiaoxiao Lin, Lujia Chen, David Baglietto-Vargas, Parsa Kamalipour, Qiao Ye, Frank M. LaFerla, Douglas A. Nitz, Todd C. Holmes, Xiangmin Xu
Publikováno v:
Neurobiology of Disease, Vol 162, Iss , Pp 105562- (2022)
Alzheimer's disease (AD) causes progressive age-related defects in memory and cognitive function and has emerged as a major health and socio-economic concern in the US and worldwide. To develop effective therapeutic treatments for AD, we need to bett
Externí odkaz:
https://doaj.org/article/f667be4f8aaf42f4b2c182b542f8b9f2
Autor:
Xiaoxiao Lin, Michelle Amalraj, Crisylle Blanton, Brenda Avila, Todd C Holmes, Douglas A Nitz, Xiangmin Xu
Publikováno v:
PLoS Biology, Vol 19, Iss 12, p e3001127 (2021)
The hippocampal formation (HF) is well documented as having a feedforward, unidirectional circuit organization termed the trisynaptic pathway. This circuit organization exists along the septotemporal axis of the HF, but the circuit connectivity acros
Externí odkaz:
https://doaj.org/article/1392e16d33eb48a5a2c0ae403b22abb2
Corners are a cardinal feature of many of the complex environmental geometries found in the natural world but the neural substrates that could underlie the perception of corners remain elusive. Here we show that the dorsal subiculum contains neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0220b3b6599f96e50af4dad000fc7ea
https://doi.org/10.1101/2023.05.07.539721
https://doi.org/10.1101/2023.05.07.539721
Autor:
Hai, Zhang, Lujia, Chen, Kevin G, Johnston, Joshua, Crapser, Kim N, Green, Nicole My-Linh, Ha, Andrea J, Tenner, Todd C, Holmes, Douglas A, Nitz, Xiangmin, Xu
A key challenge in developing diagnosis and treatments for Alzheimer's disease (AD) is to detect abnormal network activity at as early a stage as possible. To date, behavioral and neurophysiological investigations in AD model mice have yet to conduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c742778d70ca1ad41f7a7612d1085e34
https://escholarship.org/uc/item/4xs9b7xc
https://escholarship.org/uc/item/4xs9b7xc
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(45)
Humans and other animals have a remarkable capacity to translate their position from one spatial frame of reference to another. The ability to seamlessly move between top-down and first-person views is important for navigation, memory formation, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759c61185b9c0a9c3123fd4800dc6d8e
https://pubmed.ncbi.nlm.nih.gov/36322732
https://pubmed.ncbi.nlm.nih.gov/36322732
Publikováno v:
Neuron.
The last decade has produced exciting new ideas about retrosplenial cortex (RSC) and its role in integrating diverse inputs. Here, we review the diversity in forms of spatial and directional tuning of RSC activity, temporal organization of RSC activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3bd2072e356d54444d169218a16aac3
https://pubmed.ncbi.nlm.nih.gov/36460006
https://pubmed.ncbi.nlm.nih.gov/36460006
Autor:
Lujia Chen, Todd C. Holmes, Douglas A. Nitz, Xiaoxiao Lin, Parsa Kamalipour, Qiao Ye, Xiangmin Xu, Frank M. LaFerla, David Baglietto-Vargas
Publikováno v:
Neurobiology of Disease, Vol 162, Iss, Pp 105562-(2022)
Alzheimer's disease (AD) causes progressive age-related defects in memory and cognitive function and has emerged as a major health and socio-economic concern in the US and worldwide. To develop effective therapeutic treatments for AD, we need to bett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a098a44753d44f95efeb3df29834e66
https://escholarship.org/uc/item/4pw3m233
https://escholarship.org/uc/item/4pw3m233