Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Douglas A, Cotanche"'
Autor:
Sang Goo Lee, Mingqian Huang, Nikolaus D Obholzer, Shan Sun, Wenyan Li, Marco Petrillo, Pu Dai, Yi Zhou, Douglas A Cotanche, Sean G Megason, Huawei Li, Zheng-Yi Chen
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157768 (2016)
Unlike mammals, the non-mammalian vertebrate inner ear can regenerate the sensory cells, hair cells, either spontaneously or through induction after hair cell loss, leading to hearing recovery. The mechanisms underlying the regeneration are poorly un
Externí odkaz:
https://doaj.org/article/a977683193b1418bb952f2eda1167dbf
Autor:
Phillip M Uribe, Melissa A Mueller, Julia S Gleichman, Matthew D Kramer, Qi Wang, Martha Sibrian-Vazquez, Robert M Strongin, Peter S Steyger, Douglas A Cotanche, Jonathan I Matsui
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55359 (2013)
Inner ear sensory hair cells die following exposure to aminoglycoside antibiotics or chemotherapeutics like cisplatin, leading to permanent auditory and/or balance deficits in humans. Zebrafish (Danio rerio) are used to study drug-induced sensory hai
Externí odkaz:
https://doaj.org/article/b116195554ee4a2f8054da3a74a41066
Publikováno v:
Journal of Biocommunication. 42
Embryology is essential for future health-care providers to understand due to clinical significance, since birth defects and prematurity are leading causes of disability and infant mortality. The lack of embryology visualizations presents a barrier t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4919ca30fd7cbf2d51a2a533c30c11e0
https://doi.org/10.5210/jbc.v42i2.9562
https://doi.org/10.5210/jbc.v42i2.9562
Autor:
Samantha Bond, Douglas A. Cotanche, Christina Sidorowych, Leah Lebowicz, Kevin Brennan, John Daugherty, Callum Ross
Publikováno v:
Journal of Biocommunication. 42
Data from the Virtual Human Embryo Project, a digital image database of serially sectioned human embryos from the Carnegie collection, was used to visualize and create 3D reconstructions of multiple embryonic stages. Using these reconstructions as re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eafe402124bf5fefeb661466c73ca78b
https://doi.org/10.5210/jbc.v42i1.9195
https://doi.org/10.5210/jbc.v42i1.9195
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8a6b0369a69f0b63a6b8166779ce8e9
https://doi.org/10.1096/fasebj.2018.32.1_supplement.635.28
https://doi.org/10.1096/fasebj.2018.32.1_supplement.635.28
Autor:
Zach Tan, Jack Zakrzewski, Miloni Shah, Pouyan Kheirkhah, Kimberly Hu, Brandon L. Neisewander, Kalpesh Shah, Douglas A. Cotanche, Ankit I. Mehta, Darian R. Esfahani, Prateek Kumar
Publikováno v:
World neurosurgery. 116
Objective Approximately 12% of intracerebral hemorrhages (ICHs) occur in the thalamus. Understanding the anatomic regions involved with thalamic hemorrhages is potentially useful, offering the physician a more accurate prognosis for patient outcomes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9acf5b18f16e9e514df2bed5c50daa
https://pubmed.ncbi.nlm.nih.gov/29772365
https://pubmed.ncbi.nlm.nih.gov/29772365
Autor:
Marco Petrillo, Shan Sun, Mingqian Huang, Nikolaus D. Obholzer, Huawei Li, Wenyan Li, Zheng-Yi Chen, Pu Dai, Douglas A. Cotanche, Sang Goo Lee, Yi Zhou, Sean G. Megason
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 6, p e0157768 (2016)
PLoS ONE, Vol 11, Iss 6, p e0157768 (2016)
Unlike mammals, the non-mammalian vertebrate inner ear can regenerate the sensory cells, hair cells, either spontaneously or through induction after hair cell loss, leading to hearing recovery. The mechanisms underlying the regeneration are poorly un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5defd1e67e4adc53e80caa07844c4852
https://pubmed.ncbi.nlm.nih.gov/27351484
https://pubmed.ncbi.nlm.nih.gov/27351484
Autor:
Douglas A. Cotanche
Publikováno v:
Journal of Communication Disorders. 41:421-443
Twenty years ago it was first demonstrated that birds could regenerate their cochlear hair cells following noise damage or aminoglycoside treatment. An understanding of how this structural and functional regeneration occurred might lead to the develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcbdfc1bf019069006bcbc088b75786
https://doi.org/10.1016/j.jcomdis.2008.03.004
https://doi.org/10.1016/j.jcomdis.2008.03.004
Autor:
Douglas A. Cotanche, Brittany J. Chapman, Dominic A. Mangiardi, Jessica L. Guidi, Caitlin E. Terry, Christina L. Kaiser
Publikováno v:
Hearing Research. 240:1-11
Aminoglycoside antibiotics induce caspase-dependent apoptotic death in cochlear hair cells. Apoptosis, a regulated form of cell death, can be induced by many stressors, which activate signaling pathways that result in the controlled dismantling of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d1b685397c07193439d75185184565
https://doi.org/10.1016/j.heares.2008.03.003
https://doi.org/10.1016/j.heares.2008.03.003
Publikováno v:
Biomaterials. 29:1028-1042
The overall goal of this work is to improve the culture of the auditory organ of birds for the dual use of developing a hair cell regeneration model and charting a pathway to the eventual replacement of the hearing organ. In doing so, we develop a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769aa36274b0252955649c4b9fd6552f
https://doi.org/10.1016/j.biomaterials.2007.11.006
https://doi.org/10.1016/j.biomaterials.2007.11.006