Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Douglas A, Bakan"'
Autor:
Brenda A. Klaunberg, James F. Powers, Daniel Schimel, Edwin W. Lai, Karel Pacak, Shoichiro Ohta, Douglas A. Bakan, John C. Morris, Susannah Cleary, Arthur S. Tischler, Mones Abu-Asab
Publikováno v:
International Journal of Cancer. 119:2236-2241
Successful outcomes for patients with cancer often depend on the early detection of tumor and the prompt initiation of active therapy. Despite major advances in the treatment of many cancers, early-stage lesions often go undetected due to the subopti
Publikováno v:
Pharmaceutical Research. 13:875-879
Purpose. A formulation methodology for the incorporation of polyiodinated triglyceride (ITG) analogues into a protein-free chylomicron remnant-like emulsion was developed to provide a vehicle for the selective hepatic delivery of these agents for con
Autor:
Shoichiro, Ohta, Edwin W, Lai, John C, Morris, Douglas A, Bakan, Brenda, Klaunberg, Susannah, Cleary, James F, Powers, Arthur S, Tischler, Mones, Abu-Asab, Daniel, Schimel, Karel, Pacak
Publikováno v:
International journal of cancer. 119(9)
Successful outcomes for patients with cancer often depend on the early detection of tumor and the prompt initiation of active therapy. Despite major advances in the treatment of many cancers, early-stage lesions often go undetected due to the subopti
Autor:
Fred T. Lee, Susan G. Chosy, Douglas A. Bakan, Alan H. Rappe, Jamey P. Weichert, Eberhard Mack
Publikováno v:
Academic Radiology. 3:S449-S451
Publikováno v:
Academic radiology. 9
Autor:
Julie K. Doerr-stevens, Jamey P. Weichert, Marc A. Longino, Susan G. Chosy, B. Keegan Markhardt, Fred T. Lee, Yigal Greener, Anne Killam Bonneville, Cheryl Delaney, Cindy Burrascano, Douglas A. Bakan
Publikováno v:
Academic radiology. 9
RATIONALE AND OBJECTIVES In spite of the widespread use of water-soluble contrast media for computed tomography (CT), an organ-selective contrast agent is still seen as a desirable goal of radiology research (1–3). With its high incidence of primar
Autor:
Julie K. Doerr-stevens, Fred T. Lee, Douglas A. Bakan, Marc A. Longino, Raymond E. Counsell, Jamey P. Weichert
Publikováno v:
American journal of therapeutics. 8(5)
Rationale and objectives DHOG-LE is an injectable polyiodinated triglyceride lipid emulsion providing contrast enhancement of the liver in CT. Studies were conducted to characterize the imaging efficacy of various DHOG-LE formulations as a function o
Autor:
Robert H. Tambeaux, Janet E. Kuhlman, Ian A. Sproat, Sauen G. Naidu, Jamey P. Weichert, Susan G. Chosy, Fred T. Lee, Douglas A. Bakan, Stanley Goldfarb
Publikováno v:
Radiology. 203(2)
To compare findings at computed tomography (CT) enhanced with a hepatocyte-selective contrast agent (iodinated triglyceride) and/or iohexol and at CT during arterial portography (CTAP).Rabbit livers were directly inoculated with VX2 carcinoma. Result
Publikováno v:
Journal of pharmaceutical sciences. 85(9)
A synthetic lipid emulsion (LE) has been developed with physicochemical properties that closely resemble those of a specific class of naturally-occurring lipoproteins known as chylomicron remnants. The formulation has the potential to serve as a hepa
Autor:
Michael G. Spigarelli, Tso Sheng Chou, Jamey P. Weichert, Douglas A. Bakan, Marc A. Longino, Raymond E. Counsell, Susan W. Schwendner
Publikováno v:
Journal of medicinal chemistry. 38(4)
A series of glyceryl 2-oleoyl 1,3-bis[omega-(3-amino-2,4,6-triiodophenyl)] alkanoates was synthesized, radioiodinated with iodine-125, emulsified, and evaluated for their ability to selectively localize in the liver for potential use as hepatographic