Zobrazeno 1 - 10
of 467
pro vyhledávání: '"Douglas, AD"'
Publikováno v:
Nature Biotechnology. 41:314-316
Autor:
Swanson, PA, Padilla, M, Hoyland, W, McGlinchey, K, Fields, PA, Bibi, S, Faust, SN, McDermott, AB, Lambe, T, Pollard, AJ, Durham, NM, Kelly, EJ, AstraZeneca/Oxford/VRC Study Group, Adlou, S, Aley, PK, Angus, B, Anslow, R, Baker, P, Bansal, H, Beveridge, A, Bridges-Webb, A, Ching, S, Cicconi, P, Clutterbuck, EA, Collins, AM, Darton, TC, Demissie, T, Dinesh, T, Douglas, AD, Duncan, CJA, Ewer, KJ, Felle, S, Ferreira, DM, Folegatti, PM, Fuskova, M, Gaudinski, M, Gilbert, SC, Goodman, AL, Gordon, I, Green, CA, Harbolick, E, Hayes, S, Hill, AVS, Hill, H, Jenkin, D, Jepson, BM, Kasanyinga, M, Libri, V, Lillie, PJ, McGregor, AC, Minassian, AM, Mujadidi, YF, Novik, L, Payne, R, Pilataxi, F, Plested, E, Provstgaard-Morys, S, Ramasamy, M, Robinson, H, Sanders, K, Smith, A, Snape, MD, Song, R, Sutherland, RK, Thomson, EC, Toshner, M, Turner, DPJ, Voysey, M, Widge, AT, Williams, CJ
AZD1222 (ChAdOx1 nCoV-19), a replication-deficient simian adenovirus-vectored vaccine, has demonstrated safety, efficacy, and immunogenicity against coronavirus disease 2019 (COVID-19) in clinical trials and real-world studies. We characterized CD4+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::993e6e80c4502ef8c2b6b487068309ee
https://eprints.whiterose.ac.uk/178925/1/scitranslmed.abj7211.pdf
https://eprints.whiterose.ac.uk/178925/1/scitranslmed.abj7211.pdf
Autor:
Feng, S, Phillips, DJ, White, T, Sayal, H, Aley, PK, Bibi, S, Dold, C, Fuskova, M, Gilbert, SC, Hirsch, I, Humphries, HE, Jepson, B, Kelly, EJ, Plested, E, Shoemaker, K, Thomas, KM, Vekemans, J, Villafana, TL, Lambe, T, Pollard, AJ, Voysey, M, Adlou, S, Allen, L, Angus, B, Anslow, R, Asselin, M-C, Baker, N, Baker, P, Barlow, T, Beveridge, A, Bewley, KR, Brown, P, Brunt, E, Buttigieg, KR, Camara, S, Charlton, S, Chiplin, E, Cicconi, P, Clutterbuck, EA, Collins, AM, Coombes, NS, Clemens, SAC, Davison, M, Demissie, T, Dinesh, T, Douglas, AD, Duncan, CJA, Emary, KRW, Ewer, KJ, Felle, S, Ferreira, DM, Finn, A, Folegatti, PM, Fothergill, R, Fraser, S, Garlant, H, Gatcombe, L, Godwin, KJ, Goodman, AL, Green, CA, Hallis, B, Hart, TC, Heath, PT, Hill, H, Hill, AVS, Jenkin, D, Kasanyinga, M, Kerridge, S, Knight, C, Leung, S, Libri, V, Lillie, PJ, Marinou, S, McGlashan, J, McGregor, AC, McInroy, L, Minassian, AM, Mujadidi, YF, Penn, EJ, Petropoulos, CJ, Pollock, KM, Proud, PC, Provstgaard-Morys, S, Rajapaska, D, Ramasamy, MN, Sanders, K, Shaik, I, Singh, N, Smith, A, Snape, MD, Song, R, Shrestha, S, Sutherland, RK, Thomson, EC, Turner, DPJ, Webb-Bridges, A, Wrin, T, Williams, CJ
Publikováno v:
Nature Medicine
The global supply of COVID-19 vaccines remains limited. An understanding of the immune response that is predictive of protection could facilitate rapid licensure of new vaccines. Data from a randomized efficacy trial of the ChAdOx1 nCoV-19 (AZD1222)
Autor:
Illingworth, JJ, Alanine, DG, Brown, R, Marshall, JM, Bartlett, HE, Silk, SE, Labbé, GM, Quinkert, D, Cho, JS, Wendler, JP, Pattinson, DJ, Barfod, L, Douglas, AD, Shea, MW, Wright, KE, De Cassan, SC, Higgins, MK, Draper, SJ
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
The malaria genome encodes over 5,000 proteins and many of these have also been proposed to be potential vaccine candidates, although few of these have been tested clinically. RH5 is one of the leading blood-stage Plasmodium falciparum malaria vaccin
Autor:
Sheehy, SH, Duncan, CJ, Elias, SC, Choudhary, P, Biswas, S, Halstead, FD, Collins, KA, Edwards, NJ, Douglas, AD, Anagnostou, NA, Ewer, KJ, Havelock, T, Mahungu, T, Bliss, CM, Miura, K, Poulton, ID, Lillie, PJ, Antrobus, RD, Berrie, E, Moyle, S, Gantlett, K, Colloca, S, Cortese, R, Long, CA, Sinden, RE, Gilbert, SC, Lawrie, AM, Doherty, T, Faust, SN, Nicosia, A, Hill, AV, Draper, SJ
Publikováno v:
Molecular Therapy; Vol 20
The induction of cellular immunity, in conjunction with antibodies, may be essential for vaccines to protect against blood-stage infection with the human malaria parasite Plasmodium falciparum. We have shown that prime-boost delivery of P. falciparum
Autor:
Jin, J, Hjerrild, KA, Silk, SE, Brown, RE, Labbé, GM, Marshall, JM, Wright, KE, Bezemer, S, Clemmensen, SB, Biswas, S, Li, Y, El-Turabi, A, Douglas, AD, Hermans, P, Detmers, FJ, de Jongh, WA, Higgins, MK, Ashfield, R, Draper, S
Publikováno v:
International Journal for Parasitology.
Development of bespoke biomanufacturing processes remains a critical bottleneck for translational studies, in particular when modest quantities of a novel product are required for proof-of-concept Phase I/II clinical trials. In these instances the ab
Autor:
Hodgson, SH, Ewer, KJ, Bliss, CM, Edwards, NJ, Rampling, T, Anagnostou, NA, de Barra, E, Havelock, T, Bowyer, G, Poulton, ID, de Cassan, S, Longley, R, Illingworth, JJ, Douglas, AD, Mange, PB, Collins, KA, Roberts, R, Gerry, S, Berrie, E, Moyle, S, Colloca, S, Cortese, R, Sinden, RE, Gilbert, SC, Bejon, P, Lawrie, AM, Nicosia, A, Faust, SN, Hill, AV
Publikováno v:
The Journal of Infectious Diseases
Background: Circumsporozoite protein (CS) is the antigenic target for RTS,S, the most advanced malaria vaccine to date. Heterologous prime-boost with the viral vectors simian adenovirus 63 (ChAd63)-modified vaccinia virus Ankara (MVA) is the most pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::76aa1800a4aa2a5df96b5a1ffe0a3cf7
https://doi.org/10.1093/infdis/jiu579
https://doi.org/10.1093/infdis/jiu579
Akademický článek
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Autor:
Douglas, Adam Thomas
Enhancers are cis-regulatory sequences which promote the expression of target genes in a spatial and temporal fashion. They can be located within genes or between them and can act at distances of over 1 Mb. There are several different mechanisms by w
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.723883