Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies

Autor: DiJoseph, John F., Armellino, Douglas C., Boghaert, Erwin R., Khandke, Kiran, Dougher, Maureen M., Sridharan, Latha, Kunz, Arthur, Hamann, Philip R., Gorovits, Boris, Udata, Chandrasekhar, Moran, Justin K., Popplewell, Andrew G., Stephens, Sue, Frost, Philip, Damle, Nitin K. ^*

Publikováno v: In Blood 1 March 2004 103(5):1807-1814

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Thrombocytopenia Induced by CMC-544 and Its Amelioration Using Oprelvekin (Neumega®/Recombinant Human Interleukin-11).

Autor: DiJoseph, John F. ^*, Walker, Dana ^*, Dougher, Maureen M. ^*, Armellino, Doug C. ^*, Clarke, Dave ^*, Damle, Nitin K. ^*

Publikováno v: In Blood 16 November 2006 108(11):2516-2516

Antitumor efficacy of a combination of CMC-544 (inotuzumab ozogamicin), a CD22-targeted cytotoxic immunoconjugate of calicheamicin, and rituximab against non-Hodgkin's B-cell lymphoma.

Autor: DiJoseph JF; Oncology Discovery Research, Wyeth Research, Pearl River, New York 10965, USA., Dougher MM, Kalyandrug LB, Armellino DC, Boghaert ER, Hamann PR, Moran JK, Damle NK

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2006 Jan 01; Vol. 12 (1), pp. 242-9.

Antibody-targeted chemotherapy with the calicheamicin conjugate hu3S193-N-acetyl gamma calicheamicin dimethyl hydrazide targets Lewisy and eliminates Lewisy-positive human carcinoma cells and xenografts.

Autor: Boghaert ER; Wyeth Discovery Oncology and Wyeth Discovery Chemical and Screening Sciences, Pearl River, New York, USA. Boghaee@wyeth.com, Sridharan L, Armellino DC, Khandke KM, DiJoseph JF, Kunz A, Dougher MM, Jiang F, Kalyandrug LB, Hamann PR, Frost P, Damle NK

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2004 Jul 01; Vol. 10 (13), pp. 4538-49.