Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Doug Schneider"'
Autor:
Gloria I. Perez, Matthew P. Bernard, Daniel Vocelle, Ahmed A. Zarea, Najla A. Saleh, Matthew A. Gagea, Doug Schneider, Maxine Bauzon, Terry Hermiston, Masamitsu Kanada
Publikováno v:
Vaccines, Vol 11, Iss 3, p 639 (2023)
Under physiological conditions, phosphatidylserine (PS) predominantly localizes to the cytosolic leaflet of the plasma membrane of cells. During apoptosis, PS is exposed on the cell surface and serves as an “eat-me” signal for macrophages to prev
Externí odkaz:
https://doaj.org/article/50bc23899f44422ba004514967868104
Autor:
Xiao-Yan Zhao, Andreas Wilmen, Dongli Wang, Xinquan Wang, Maxine Bauzon, Ji-Yun Kim, Lars Linden, Liang Li, Ursula Egner, Tobias Marquardt, Dieter Moosmayer, Jan Tebbe, Julian Marius Glück, Philipp Ellinger, Kirk McLean, Shujun Yuan, Subramanian Yegneswaran, Xiaoqiao Jiang, Vince Evans, Jian-Ming Gu, Doug Schneider, Ying Zhu, Yifan Xu, Cornell Mallari, Ashley Hesslein, Yan Wang, Nicole Schmidt, Katrin Gutberlet, Christine Ruehl-Fehlert, Alexius Freyberger, Terry Hermiston, Chandra Patel, Derek Sim, Laurent O. Mosnier, Volker Laux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Activated protein C (APC) is a plasma serine protease with antithrombotic and cytoprotective functions. Here, the authors develop a monoclonal antibody that specifically inhibits APC’s anticoagulant function without compromising its cytoprotective
Externí odkaz:
https://doaj.org/article/9ba7c3d64bcb4b03984dbf3b38cd94db
Autor:
Gordon Parry, Harald Dinter, Jason S. Lewis, Georg Roth, Peter Bringmann, Ronald R. Cobb, Brent Larsen, Ying Zhu, Helmut Klocker, Meredith Halks-Miller, Peter J. Kretschmer, Sandra Biroc, Bruno Alicke, Rick Harkins, Rick Lin, Pam Toy, Alicia Newton, Jian-Ai Xuan, Debbie Parkes, Debra Hudson, Doug Schneider, Renate Parry
Gene expression analysis showed that a human mindin homologue, mindin/RG-1, is expressed selectively in prostate tissues and that its expression level is elevated in some prostate tumors. Mindin/RG-1 protein expression is maintained in >80% of prosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7a6a2b5ada391d9a301dcfa36a67be
https://doi.org/10.1158/0008-5472.c.6494439.v1
https://doi.org/10.1158/0008-5472.c.6494439.v1
Autor:
Derek S Sim, Meenal Shukla, Cornell R Mallari, José A. Fernández, Xiao Xu, Doug Schneider, Maxine Bauzon, Terry W Hermiston, Laurent O. Mosnier
Publikováno v:
Blood Advances.
Activated protein C (APC) is a pleiotropic coagulation protease with anticoagulant, anti-inflammatory, and cytoprotective activities. Selective modulation of these APC activities contributes to our understanding of the regulation of these physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e216e9bfd3fd7050dbf277811243739b
https://doi.org/10.1182/bloodadvances.2022008740
https://doi.org/10.1182/bloodadvances.2022008740
Autor:
Gloria I. Perez, Matthew P. Bernard, Daniel Vocelle, Ahmed A. Zarea, Doug Schneider, Maxine Bauzon, Terry Hermiston, Masamitsu Kanada
Under physiological conditions, phosphatidylserine (PS) predominantly localizes to the cytosolic leaflet of the plasma membrane of cells. During apoptosis, PS is exposed on the cell surface and serves as an “eat-me” signal for macrophages to prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357b2770d5fb36dba8ae9cbd3902ab8d
https://doi.org/10.1101/2022.11.17.516966
https://doi.org/10.1101/2022.11.17.516966
Autor:
Derek S Sim, Meenal Shukla, Cornell R Mallari, Doug Schneider, Maxine Bauzon, Terry W Hermiston, Laurent O. Mosnier
Publikováno v:
Blood. 140:973-974
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b6b5c126ed0a0beb7855c9d8d0eee1
https://doi.org/10.1182/blood-2022-158855
https://doi.org/10.1182/blood-2022-158855
Autor:
Chandra Patel, Julian Marius Glück, Derek Sim, Shujun Yuan, Ying Zhu, Yan Wang, Terry Hermiston, Liang Li, Cornell Mallari, Dieter Moosmayer, Christine Ruehl-Fehlert, Xiaoqiao Jiang, Xiao-Yan Zhao, Katrin Gutberlet, Xinquan Wang, Dongli Wang, Laurent O. Mosnier, Jan Tebbe, Ashley Hesslein, Vince Evans, Yifan Xu, Subramanian Yegneswaran, Nicole Schmidt, Lars Linden, Andreas Wilmen, Kirk Mclean, Jian-Ming Gu, Tobias Marquardt, Doug Schneider, Ursula Egner, Philipp Ellinger, Volker Laux, Ji-Yun Kim, Alexius Freyberger, Maxine Bauzon
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Activated protein C (APC) is a plasma serine protease with antithrombotic and cytoprotective functions. Based on the hypothesis that specific inhibition of APC’s anticoagulant but not its cytoprotective activity can be beneficial for hemophilia the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb59b9c0dc462528b55e42fb2e14e4c0
http://europepmc.org/articles/PMC7293249
http://europepmc.org/articles/PMC7293249
Autor:
Theodora Hatziioannou, Charles M. Trubey, Fang Yuan, Jeremy Smedley, Michael Piatak, Jeffrey D. Lifson, Rebecca Kiser, Jacob D. Estes, Paul D. Bieniasz, Ronald S. Veazey, Vineet N. KewalRamani, Vicky Coalter, Nancy P. Y. Chung, Doug Schneider, Zandrea Ambrose, Rhonda Pung, Mercy Gathuka
Publikováno v:
Proceedings of the National Academy of Sciences. 106:4425-4429
The lack of a primate model that utilizes HIV-1 as the challenge virus is an impediment to AIDS research; existing models generally employ simian viruses that are divergent from HIV-1, reducing their usefulness in preclinical investigations. Based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94e56acfcbe6245bdba78de509ca48f
https://doi.org/10.1073/pnas.0812587106
https://doi.org/10.1073/pnas.0812587106
Autor:
Harald Dinter, Peter J. Kretschmer, Rick Lin, Debra Hudson, Doug Schneider, Pam Toy, Meredith Halks-Miller, Alicia Newton, Ronald R. Cobb, Gordon Parry, Bruno Alicke, Peter Bringmann, Georg A. Roth, Renate Parry, Jian-Ai Xuan, Helmut Klocker, Debbie Parkes, Sandra Biroc, Brent R. Larsen, Jason S. Lewis, Ying Zhu, Rick Harkins
Publikováno v:
Cancer Research. 65:8397-8405
Gene expression analysis showed that a human mindin homologue, mindin/RG-1, is expressed selectively in prostate tissues and that its expression level is elevated in some prostate tumors. Mindin/RG-1 protein expression is maintained in >80% of prosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f2d5e90ff1d7eaad3e6c6a9d0ea9d5
https://doi.org/10.1158/0008-5472.can-05-1203
https://doi.org/10.1158/0008-5472.can-05-1203
Autor:
Derek Sim, Xiaoqiao Jiang, Maxine Bauzon, Charles T. Esmon, Vince Evans, Jian-Ming Gu, Subramanian Yegneswaran, Jun Xu, Xiao-Yan Zhao, Chandra Patel, Peter Bringmann, Katalin Kauser, Kirk Mclean, Inge A. Ivens, Doug Schneider, Ying Zhu
Publikováno v:
Blood. 128:80-80
In patients with hemophilia, hereditary defects in coagulation factors result in unstable clots and recurrent bleeding. Although the current standard of care focuses on replacement factor therapy, we propose that inhibition of the anticoagulant pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dd3df4807dca9980f6c520b1d9ebb5d
https://doi.org/10.1182/blood.v128.22.80.80
https://doi.org/10.1182/blood.v128.22.80.80