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Autor:
Gabriel E. Hoffman, Doug Ruderfer, Erin Flaherty, Kristen J. Brennand, Brigham J. Hartley, Peter Gochman, Pamela Sklar, Judith L. Rapoport, Ian Ladran
Publikováno v:
European Neuropsychopharmacology. 29:S1008
Background Large-scale Genome Wide Association Studies (GWAS) revealed that Schizophrenia (SZ) risk reflects both rare and common variants. Whereas highly penetrant rare variants have proven well-suited to human induced pluripotent stem cell (hiPSC)-