Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Doug R, Braun"'
Autor:
Jia-Xuan Yan, Qihao Wu, Eric J. N. Helfrich, Marc G. Chevrette, Doug R. Braun, Heino Heyman, Gene E. Ananiev, Scott R. Rajski, Cameron R. Currie, Jon Clardy, Tim S. Bugni
Publikováno v:
Marine Drugs, Vol 20, Iss 1, p 43 (2022)
Chemical investigations of a marine sponge-associated Bacillus revealed six new imidazolium-containing compounds, bacillimidazoles A–F (1–6). Previous reports of related imidazolium-containing natural products are rare. Initially unveiled by tims
Externí odkaz:
https://doaj.org/article/a30b31fd6e384582b8f6a2e573d9c658
Autor:
Qihao Wu, Bailey A. Bell, Jia-Xuan Yan, Marc G. Chevrette, Nathan J. Brittin, Yanlong Zhu, Shaurya Chanana, Mitasree Maity, Doug R. Braun, Amelia M. Wheaton, Ilia A. Guzei, Ying Ge, Scott R. Rajski, Michael G. Thomas, Tim S. Bugni
Publikováno v:
Journal of the American Chemical Society. 145:58-69
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb66b0561e4ca0a67d5f0d392c8f53a8
https://doi.org/10.1021/jacs.2c06410
https://doi.org/10.1021/jacs.2c06410
Autor:
Fan Zhang, René F. Ramos Alvarenga, Kurt Throckmorton, Shaurya Chanana, Doug R. Braun, Jen Fossen, Miao Zhao, Sue McCrone, Mary Kay Harper, Scott R. Rajski, Warren E. Rose, David R. Andes, Michael G. Thomas, Tim S. Bugni
Publikováno v:
Organic Letters. 24:3998-4002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f5f48ae113e81ba77f48fde277da3bf
https://doi.org/10.1021/acs.orglett.2c01408
https://doi.org/10.1021/acs.orglett.2c01408
Autor:
Chris S. Thomas, Doug R. Braun, Jose Luis Olmos, Scott R. Rajski, George N. Phillips, David N. Andes, Tim S. Bugni
Publikováno v:
Marine Drugs, Vol 18, Iss 6, p 295 (2020)
Carbapenem-resistant Enterobacteriaceae continue to threaten human health worldwide with few effective treatment options. New Delhi metallo--lactamase (NDM) enzymes are a contributing element that drive resistance to many -lactam- and carbapenem-base
Externí odkaz:
https://doaj.org/article/25ff0121c3cd4c9f9d6fb77706e60f59
Autor:
Navid Adnani, Emmanuel Vazquez-Rivera, Srikar N. Adibhatla, Gregory A. Ellis, Doug R. Braun, Tim S. Bugni
Publikováno v:
Marine Drugs, Vol 13, Iss 10, Pp 6082-6098 (2015)
With respect to bacterial natural products, a significant outcome of the genomic era was that the biosynthetic potential in many microorganisms surpassed the number of compounds isolated under standard laboratory growth conditions, particularly among
Externí odkaz:
https://doaj.org/article/9dee2ea4bc7e45d78a182bd5388a9750
Autor:
Gregory A Ellis, Chris S Thomas, Shaurya Chanana, Navid Adnani, Emily Szachowicz, Doug R Braun, Mary Kay Harper, Thomas P Wyche, Tim S Bugni
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0176968 (2017)
Bacterial communities associated with marine invertebrates such as sponges and ascidians have demonstrated potential as sources of bio-medically relevant small molecules. Metagenomic analysis has shown that many of these invertebrates harbor populati
Externí odkaz:
https://doaj.org/article/871d33758d394894b03b0345c2ea0554
Autor:
Marc G. Chevrette, Cameron R. Currie, Qihao Wu, Doug R. Braun, Tim S. Bugni, Mitasree Maity, Scott R. Rajski, Michael G. Thomas, Kurt Throckmorton
Publikováno v:
Journal of Natural Products. 84:136-141
Chemical investigation of a marine sponge-associated Bacillus sp. led to the discovery of bacillibactins E and F (1 and 2). Despite containing the well-established cyclic triester core of iron-binding natural products such as enterobactin, bacillibac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efb7d52f1dae6eaa24350b5a51b8468b
https://doi.org/10.1021/acs.jnatprod.0c01170
https://doi.org/10.1021/acs.jnatprod.0c01170
Autor:
Tim S. Bugni, Jia-Xuan Yan, Mary Kay Harper, Marc G. Chevrette, Cameron R. Currie, Doug R. Braun
Publikováno v:
Organic Letters. 21:6275-6279
Two new siderophores, madurastatin D1 and D2, together with (-)-madurastatin C1, the enantiomer of a known compound, were isolated from marine-derived Actinomadura sp. The presence of an unusual 4-imidazolidinone ring in madurastatins D1 and D2 inspi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f7fb58b0a989cb41b1ec8b25e348438
https://doi.org/10.1021/acs.orglett.9b02159
https://doi.org/10.1021/acs.orglett.9b02159
Publikováno v:
Journal of Natural Products. 82:1930-1934
Here we report the discovery of two new 3-acetamido-4-hydroxybenzoate esters, bulbiferates A (1) and B (2), isolated from Microbulbifer sp. cultivated from the marine tunicate Ecteinascidia turbinata. The structures of 1 and 2 were determined by anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7806c0173167857436ad8bee17b6a9de
https://doi.org/10.1021/acs.jnatprod.9b00312
https://doi.org/10.1021/acs.jnatprod.9b00312
Autor:
Helen E. Blackwell, Jason C. Kwan, Matthew J. Styles, Yusi Cui, Deepa D. Acharya, Ian J. Miller, Scott R. Rajski, Doug R. Braun, Tim S. Bugni, Lingjun Li, Mark E. Berres
Publikováno v:
ACS Chemical Biology. 14:1260-1270
[Image: see text] DNA sequencing of a large collection of bacterial genomes reveals a wealth of orphan biosynthetic gene clusters (BGCs) with no identifiable products. BGC silencing, for those orphan clusters that are truly silent, rather than those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1edc192a657a75da1e72b75ac526aa9
https://doi.org/10.1021/acschembio.9b00223
https://doi.org/10.1021/acschembio.9b00223