Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Doug P. Nesta"'
Autor:
John H. A. Amery, Stefan Andreas Lange, Hill Malcolm Leithhead, Robert Simler, Leigh Dixon, Frank Gielen, Cinzia Gazziola, Doug P. Nesta, Jale Muslehiddinoglu, Kirsten Storch, Claudia Mueller, Jeremy D. Prail, Anna L. Watson
Publikováno v:
Nucleic Acid Therapeutics
The most common approach for the manufacture of oligonucleotides includes isolation of the active pharmaceutical ingredient (API) via lyophilization to provide a solid product, which is then dissolved to provide an aqueous formulation. It is well kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0aaafb3daa2f2511a77619b48c69f0a
https://doi.org/10.1089/nat.2020.0846
https://doi.org/10.1089/nat.2020.0846
Autor:
James D. Colandene, Shubhadra N. Singh, Ning Wang, Doug P. Nesta, Rachel Forcino, Valeriy Bondar, Swati Kumar
Publikováno v:
International journal of pharmaceutics. 552(1-2)
The study explores new benefits of controlled ice nucleation during lyophilization. A highly concentrated monoclonal antibody product was lyophilized using conventional (uncontrolled) and controlled ice nucleation freezing and the processes were comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46146928ba2d2216af645e8e065e9015
https://pubmed.ncbi.nlm.nih.gov/30261214
https://pubmed.ncbi.nlm.nih.gov/30261214
Autor:
Karoline Bechtold-Peters, Jeffrey T. Blue, Hanns-Christian Mahler, Mary E.M. Cromwell, Michel Awwad, Satish K. Singh, Thomas Spitznagel, Doug P. Nesta, Danny K. Chou, Hans-Juergen Krause, Nataliya Afonina, Brian K. Meyer, Linda O. Narhi
Publikováno v:
Journal of Pharmaceutical Sciences. 99:3302-3321
Concern around the lack of monitoring of proteinaceous subvisible particulates in the 0.1-10 microm range has been heightened (Carpenter et al., 2009, J Pharm Sci 98: 1202-1205), primarily due to uncertainty around the potential immunogenicity risk f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da6cbebd9afebc1062b8e250b485ee8
https://doi.org/10.1002/jps.22097
https://doi.org/10.1002/jps.22097