Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Doug Minick"'
Autor:
Pier D’Alessandro, Doug Minick, Sonia Delle-Fratte, Sharon Butler, Paul W. Smith, Adelheid Roth, Stephen P. Watson, Ezio Bettini, Vincenzo Garzya, Michela Andreoli, Caroline J. Goodacre, Palmina Cavallini, Roberto Benedetti, Catherine Ball, Parita Shah, Olivier Lorthioir, Fiona Brown, Ben Tehan, Maria Pilla, Michela Tessari
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:7521-7524
The identification of novel orally active mGluR5 antagonist GSK2210875 is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa12e751e46fedaf386b6e02c37c69b
https://doi.org/10.1016/j.bmcl.2010.09.120
https://doi.org/10.1016/j.bmcl.2010.09.120
Autor:
Doug Minick, Gary E. Martin, Virgil L. Styles, Janet L. Rideout, Cecilia S. Koble, Robert L. Johnson, Ronald C. Crouch, William R. Hall, James Cichetti
Publikováno v:
Journal of Heterocyclic Chemistry. 28:1795-1799
A minor impurity was recorded by hplc during the final purification of synthetically prepared samples of the 5′-0-glucuronide of azidothymidine (GAZT). Following isolation of a small quantity of this impurity by hplc, elucidation of the structure w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e3294b8b1f1a590afed6000547e832c
https://doi.org/10.1002/jhet.5570280724
https://doi.org/10.1002/jhet.5570280724
Autor:
Ronald C. Crouch, Gary E. Martin, Charles H. Phoebe, Doug Minick, Paul L. Schiff, Maged H. M. Sharaf, Robert L. Johnson, Albert N. Tackie, C. Webster Andrews
Publikováno v:
Journal of Heterocyclic Chemistry. 33:789-797
The isolation and structure determination of cryptomisrine, a novel indolo[3,2-b]quinoline dimeric alkaloid obtained from extracts of the roots of the Ghanaian medicinal plant Cryptolepis sanguinolenta is reported. The structure determination was mad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41fb1ac07b89b8ca933510497a3de584
https://doi.org/10.1002/jhet.5570330343
https://doi.org/10.1002/jhet.5570330343
Autor:
John P. Shockcor, Layne Howard, Carol Meyers, Albert N. Tackie, Chad E. Hadden, Robert L. Johnson, Charles H. Phoebe, C. Webster Andrews, Maged H. M. Sharaf, Ronald C. Crouch, Susan K. Wrenn, Ann O. Davis, Gary E. Martin, Doug Minick, Paul L. Schiff
Publikováno v:
Magnetic Resonance in Chemistry. 33:767-778
Cryptolepis sanguinolenta (Lindl.) Schlechter (Asclepiadaceae), a shrub indigenous to West Africa, has been employed by traditional healers in the treatment of various fevers, including malaria. Column chromatography of the alkaloid fraction obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c4e3a652ee8f25bf4e08b7c798b1b97
https://doi.org/10.1002/mrc.1260331003
https://doi.org/10.1002/mrc.1260331003
Autor:
Paul R. Johnson, Dallas K. Croom, Sarah R. Bullard, Sean Ross, Ronald L. Brashear, James M. Way, Christopher R. Conlee, Shane M. Hart, Carina Ammala, Vicente Samano, James B. Thompson, Doug Minick, Yun Xu, Dennis Heyer, Shane Roller, Eric E. Boros, Sarva M. Tadepalli, Peckham Gregory, Andrew J. Carpenter, Jennifer A. Kashatus, Subba Reddy Katamreddy, Howard Ray Sauls, Richard Dana Caldwell, Celia P. Briscoe
Publikováno v:
Journal of medicinal chemistry. 55(24)
GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042ec05713cf4401600aefc83d2b88d2
https://pubmed.ncbi.nlm.nih.gov/23214471
https://pubmed.ncbi.nlm.nih.gov/23214471
Autor:
Ronald C. Crouch, Timothy D. Spitzer, Maged H. M. Sharaf, Robert L. Johnson, Doug Minick, Paul L. Schiff, A.N. Tackie, John Dunn, Gary E. Martin, Gilbert L. Boye
Publikováno v:
Journal of Natural Products. 56:653-670
From the alkaloidal fractions of the West African plant Cryptolepis sanguinolenta (Asclepiadaceae), two alkaloids were purified: one was identified as the known indoloquinoline alkaloid cryptolepine [1]. A second, novel alkaloid has shown to have an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17f514dd9d6205e31fbde915bdd3ff77
https://doi.org/10.1021/np50095a001
https://doi.org/10.1021/np50095a001
Autor:
Cecilia S. Koble, Doug Minick, James Cichetti, Gary E. Martin, Ronald C. Crouch, Janet L. Rideout, Virgil L. Styles, William R. Hall, Robert L. Johnson
Publikováno v:
ChemInform. 23
A minor impurity was recorded by hplc during the final purification of synthetically prepared samples of the 5′-0-glucuronide of azidothymidine (GAZT). Following isolation of a small quantity of this impurity by hplc, elucidation of the structure w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b952faf19c95b81ba86eeb044322f81f
https://doi.org/10.1002/chin.199211257
https://doi.org/10.1002/chin.199211257
Autor:
Roberto Arban, Fabrizio Micheli, Silvia Davalli, Letizia Bettelini, Michele Negri, Carla Marchioro, Romano Di Fabio, Ilaria Sartori, Laura Zonzini, Barbara Bertani, Roberto Benedetti, Michela Bettati, Stefano Fontana, Giorgio Bonanomi, Doug Minick, Simone Braggio, Paolo Cavanni, Elettra Fazzolari, Anna Checchia, Alessandro Zocchi, Filippo Visentini, Kevin D. Read, Beatrice Oliosi, Giovanna Tedesco, Silvia Terreni, Luca Tarsi
Publikováno v:
Journal of medicinal chemistry. 53(6)
The discovery of new highly potent and selective triple reuptake inhibitors is reported. The new classes of 1-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes are described together with detail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2556c284c9594a624f75bb7c11524b98
https://pubmed.ncbi.nlm.nih.gov/20170186
https://pubmed.ncbi.nlm.nih.gov/20170186