Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Doug Critcher"'
Autor:
Suju Mathew, Adam Scott, Gemma Scotney, Graham Checksfield, Peter J. Dunn, Doug Critcher, Alexander Wilder, Stuart Field, Geoffrey M. H. Walker, Roger M. Howard, Laurence James Harris, Georges Assaf
Publikováno v:
Green Chem.. 14:123-129
The Pfizer Green Chemistry metrics program is described and exemplified with a case history involving the synthesis of (S,S)-reboxetine succinate. The initial route used a classical resolution approach and generated high levels of waste. This route w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d86575087e608d4402b62898e815ec
https://doi.org/10.1039/c1gc15921f
https://doi.org/10.1039/c1gc15921f
Autor:
Suju Mathew, Stewart T. Hayes, Christian T. Regius, Adam Scott, Chi Cheung, Doug Critcher, Roger M. Howard, Laurence James Harris, Georges Assaf, Graham Checksfield, Gemma Scotney
Publikováno v:
Organic Process Research & Development. 15:1305-1314
The development of a synthetic process for (S,S)-reboxetine succinate, a candidate for the treatment of fibromylagia, is disclosed from initial scale-up to deliver material for registrational stability testing through to commercial route evaluation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06d87d9b6a4f7778135c4b8937e55119
https://doi.org/10.1021/op200181f
https://doi.org/10.1021/op200181f
Autor:
Alan John Pettman, Suju Mathew, Georges Assaf, Doug Critcher, Gemma Cansell, Stewart T. Hayes, Stuart Field
Publikováno v:
Tetrahedron Letters. 51:5048-5051
We report our results on the construction of a morpholine ring system from the corresponding epoxide and amino alcohol. From this study, we were able to convert a previous four-step synthesis into a more efficient two-step process.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef211c2c4b192b3671c7c3810b0d1b85
https://doi.org/10.1016/j.tetlet.2010.07.106
https://doi.org/10.1016/j.tetlet.2010.07.106
Autor:
Stewart T. Hayes, Georges Assaf, Graham Checksfield, Chi Cheung, Doug Critcher, Laurence Harris, Roger Howard, Suju Mathew, Christian Regius, Gemma Scotney, Adam Scott
Publikováno v:
Organic Process Research & Development; Nov2011, Vol. 15 Issue 6, p1305-1314, 10p