Výsledky vyhledávání - "Doubun Hayashi"

Changes in serum cholesterol levels determine future risk of cardiovascular events in patients with acute coronary syndrome in the Japanese Coronary Artery Disease (JCAD) Study

Autor: Doubun Hayashi, Junichi Yoshikawa, Tsutomu Yamazaki, Kenei Shimada, Ryozo Nagai, Shota Fukuda, Masatoshi Fujita, Minoru Yoshiyama, Takahide Kohro

Publikováno v: Journal of Cardiology. 61(6):387-392

Background Although increased attention is given to assess absolute values of serum cholesterol profiles as optimal markers for preventing future cardiovascular (CV) events, changes in cholesterol profiles also have the potential to be associated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9424db78b887f93bc9908e247f99587b

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Treatment effects of renin-angiotensin system inhibitor and calcium channel blocker in patients with coronary artery narrowing (from the Japanese Coronary Artery Disease Study)

Autor: Takahide Kohro, Ryozo Nagai, Masatoshi Fujita, Tsutomu Yamazaki, Shigetake Sasayama, Doubun Hayashi, Fumio Terasaki, Satoko Mitani, Yoshihiro Okada, Tatsuya Morimoto

Publikováno v: Heart and Vessels. 25:453-459

Low-dose antihypertensive drugs in combination are prescribed frequently in clinical practice. Combination treatment is superior to monotherapy with higher doses of each drug in terms of blood pressure reduction and side effects. However, it is uncle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff99c5b711bad296b89fda9840a21d2
https://doi.org/10.1007/s00380-010-0012-5

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Elevated Serum Uric Acid is an Independent Predictor for Cardiovascular Events in Patients With Severe Coronary Artery Stenosis Subanalysis of the Japanese Coronary Artery Disease (JCAD) Study

Autor: Takafumi Okura, Jitsuo Higaki, Mie Kurata, Jun Irita, Ken-ichi Miyoshi, Tsutomu Yamazaki, Doubun Hayashi, Takahide Kohro, Ryozo Nagai, null The JCAD Study Investigators

Publikováno v: Circulation Journal. 73:885-891

Background: The association of elevated serum uric acid (UA) with cardiovascular events in patients with severe coronary artery stenosis was examined. Methods and Results: Patients with stenosis ≥75% (n=8,832) were followed for "all events" (cardio

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https://doi.org/10.1253/circj.cj-08-0828

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Elevated Serum C-Reactive Protein Levels Predict Cardiovascular Events in the Japanese Coronary Artery Disease (JCAD) Study

Autor: Kenei Shimada, Masatoshi Fujita, Atsushi Tanaka, Ken Yoshida, Satoshi Jisso, Hidemasa Tanaka, Junichi Yoshikawa, Takahide Kohro, Doubun Hayashi, Yoshihiro Okada, Tsutomu Yamazaki, Ryozo Nagai, null The JCAD Investigators

Publikováno v: Circulation Journal. 73:78-85

Background Accumulating evidence indicates that C-reactive protein (CRP) is an independent predictive factor for atherosclerotic vascular disease in Caucasians. Accordingly, this study sought to investigate the relationship between the serum level of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537c1da9482160c63406ea348d44d1aa
https://doi.org/10.1253/circj.cj-08-0295

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Demographics and Changes in Medical/Interventional Treatment of Coronary Artery Disease Patients Over a 3.5-Year Period in Japan The Japanese Coronary Artery Disease Study: Trend Examination

Autor: Takahide Kohro, Doubun Hayashi, Yoshihiro Okada, Tsutomu Yamazaki, Ryozo Nagai, null The JCAD Investigators

Publikováno v: Circulation Journal. 72:1397-1402

Background Cardiovascular medicine has undergone rapid changes in recent years, but there are insufficient reports using large cohorts regarding these changes for Japanese coronary artery disease (CAD) patients. Hence, a large-scale prospective obser

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https://doi.org/10.1253/circj.cj-08-0140

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The use of a supercooling refrigerator improves the preservation of organ grafts

Autor: Masashi Fukayama, Toru Hosoda, Yasuhiro Okawa, Yasushi Imai, Hiroshi Uozaki, Ryozo Nagai, Koshiro Monzen, Tomoki Nishiyama, Takahide Kohro, Doubun Hayashi

Publikováno v: Biochemical and Biophysical Research Communications. 337:534-539

Current medical transplantation confronts major problems such as the shortage of donors and geographical restrictions that inhibit efficient utilization of finite donor organs within their storage lives. To overcome these issues, expanding organ pres

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https://doi.org/10.1016/j.bbrc.2005.09.082

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Atrial natriuretic peptide inhibits cardiomyocyte hypertrophy through mitogen-activated protein kinase phosphatase-1

Autor: Yasushi Imai, Ryozo Nagai, Yunzeng Zou, Yoshio Yazaki, Masaki Shimoyama, Koichiro Harada, Koshiro Monzen, Doubun Hayashi, Issei Komuro, Ichiro Shiojima, Sumiyo Kudoh, Tsutomu Yamazaki

Publikováno v: Biochemical and Biophysical Research Communications. 322:310-319

Cardiac hypertrophy is formed in response to hemodynamic overload. Although a variety of factors such as catecholamines, angiotensin II (AngII), and endothelin-1 (ET-1) have been reported to induce cardiac hypertrophy, little is known regarding the f

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https://doi.org/10.1016/j.bbrc.2004.07.119

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Design and Rationale of the Japanese Coronary Artery Disease (JCAD) Study

Autor: Jcad study Investigators, Operation Secretariat headed by Tsutomu Yamazaki, Operation Secretariat headed by Doubun Hayashi

Publikováno v: Japanese Heart Journal. 45:895-911

Since there is in sufficient evidence on patients with coronary artery disease in Japan, the Japanese Coronary Artery Disease (JCAD) Study, in which 217 institutions participate, was designed to collect basic data based on evidence-based medicine (EB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::908b99df6f7811cbe638d48c9318c878
https://doi.org/10.1536/jhj.45.895

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Development of a Pioneering Clinical Support System Utilizing Information Technology: Clinical Informatics and Genome Analysis

Autor: Tadashi Yamazaki, Tsutomu Yamazaki, Ryozo Nagai, Doubun Hayashi, Takefumi Nojiri, Koshiro Monzen, Yasushi Imai, Hideo Fujita, Tomohiro Harada, Hiroyuki Morita

Publikováno v: Japanese Heart Journal. 45:315-324

Nowadays, evidence-based medicine has entered the mainstream of clinical judgement and the human genome has been completely decoded. Even the concept of individually designed medicine, that is, tailor-made medicine, is now being discussed. Due to the

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https://doi.org/10.1536/jhj.45.315

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Genetic variations of matrix metalloproteinase-1 and -3 promoter regions and their associations with susceptibility to myocardial infarction in Japanese

Autor: Koji Maemura, Tsutomu Yamazaki, Tadanori Aizawa, Takao Sugiyama, Doubun Hayashi, Yasunobu Hirata, Ryozo Nagai, Ken Ogasawara, Minoru Ohno, Akira Saito, Yasushi Imai, Hiroyuki Morita, Takefumi Nojiri

Publikováno v: International Journal of Cardiology. 92:181-186

Matrix metalloproteinases (MMPs) are involved in plaque rupture, which is the main pathological cause of myocardial infarction (MI). Recently, several genetic studies have demonstrated that MMP-1 1G/2G polymorphism and MMP-3 5A/6A polymorphism modify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1786bc15f0f4e096b6a466e09a840a
https://doi.org/10.1016/s0167-5273(03)00100-1

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