Designing a broad-spectrum integrative approach for cancer prevention and treatment

Autor: Block, KI, Gyllenhaal, C, Lowe, L, Amedei, A, Ruhul Amin, ARM, Amin, A, Aquilano, K, Arbiser, J, Arreola, A, Arzumanyan, A, Salman Ashraf, S, Azmi, AS, Benencia, F, Bhakta, D, Bilsland, A, Bishayee, A, Blain, SW, Block, PB, Boosani, CS, Carey, TE, Carnero, A, Carotenuto, M, Casey, SC, Chakrabarti, M, Chaturvedi, R, Chen, GZ, Chen, H, Chen, S, Chen, YC, Choi, BK, Ciriolo, MR, Coley, HM, Collins, AR, Connell, M, Crawford, S, Curran, CS, Dabrosin, C, Damia, G, Dasgupta, S, DeBerardinis, RJ, Decker, WK, Dhawan, P, Diehl, AME, Dong, JT, Dou, QP, Drewa, JE, Elkord, E, El-Rayes, B, Feitelson, MA, Felsheru, DW, Ferguson, LR, Fimognari, C, Firestone, GL, Frezza, C, Fujii, H, Fuster, MM, Generali, D, Georgakilas, AG, Gieseler, F, Gilbertson, M, Green, MF, Grue, B, Guhal, G, Halicka, D, Helferich, WG, Heneberg, P, Hentosh, P, Hirschey, MD, Hofseth, LJ, Holcombe, RF, Honoki, K, Hsu, HY, Huang, GS, Jensen, LD, Jiang, WG, Jones, LW, Karpowicz, PA, Keith, WN, Kerkar, SP, Khan, GN, Khatami, M, Ko, YH, Kucuk, O, Kulathinal, RJ, Kumar, NB, Kwon, BS, Leb, A, Leab, MA, Lee, HY, Lichtor, T, Lin, LT, Locasale, JW

Publikováno v: Block, KI; Gyllenhaal, C; Lowe, L; Amedei, A; Ruhul Amin, ARM; Amin, A; et al.(2015). Designing a broad-spectrum integrative approach for cancer prevention and treatment. Seminars in Cancer Biology, 35, S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/62d7n4g9

© 2015 The Authors. Targeted therapies and the consequent adoption of "personalized" oncology have achieved notablesuccesses in some cancers; however, significant problems remain with this approach. Many targetedtherapies are highly toxic, costs are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::b7b7b2fad02d7325bc39873f0ca1f301
http://www.escholarship.org/uc/item/62d7n4g9

Structure-proteasome-inhibitory activity relationships of dietary flavonoids in human cancer cells

Autor: Marina S. Chen, Huanjie Yang, Di Chen, Qiuzhi Cindy Cui, Dou Qp

Publikováno v: Frontiers in bioscience : a journal and virtual library. 12

Diet high in vegetables and fruits has been associated with reduced cancer risk. However, the involved mechanisms are unknown. Previously, we reported that the dietary flavonoid apigenin could inhibit the proteasome activity and induce apoptosis in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeff1b872f8a7fa3316a9881992ab946
https://pubmed.ncbi.nlm.nih.gov/17127432

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