Ivacaftor ameliorates mucus burden, bacterial load, and inflammation in acute but not chronic P. aeruginosa infection in hG551D rats.

Autor: Keith JD; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL, 35294, USA., Murphree-Terry M; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL, 35294, USA.; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Bollar G; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL, 35294, USA.; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Oden AM; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Doty IH; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Birket SE; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL, 35294, USA. susanbirket@uabmc.edu.; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. susanbirket@uabmc.edu.

Publikováno v: Respiratory research [Respir Res] 2024 Nov 04; Vol. 25 (1), pp. 397. Date of Electronic Publication: 2024 Nov 04.