Data Science-Enabled Palladium-Catalyzed Enantioselective Aryl-Carbonylation of Sulfonimidamides.

Autor: van Dijk L; Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Haas BC; Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Lim NK; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Clagg K; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Dotson JJ; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Treacy SM; Department of Chemistry, University of California, Berkeley, California 94720, United States., Piechowicz KA; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Roytman VA; Department of Chemistry, University of California, Berkeley, California 94720, United States., Zhang H; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Toste FD; Department of Chemistry, University of California, Berkeley, California 94720, United States., Miller SJ; Department of Chemistry, Yale University, New Haven, Connecticut 06511, United States., Gosselin F; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Sigman MS; Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2023 Sep 27; Vol. 145 (38), pp. 20959-20967. Date of Electronic Publication: 2023 Sep 01.

Data-Driven Multi-Objective Optimization Tactics for Catalytic Asymmetric Reactions Using Bisphosphine Ligands.

Autor: Dotson JJ; Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., van Dijk L; Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Timmerman JC; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Grosslight S; Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Walroth RC; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Gosselin F; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Püntener K; Synthetic Molecules Technical Development, Process Chemistry & Catalysis, F. Hoffmann-La Roche Limited, CH-4070 Basel, Switzerland., Mack KA; Department of Small Molecule Process Chemistry, Genentech, Inc., South San Francisco, California 94080, United States., Sigman MS; Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2023 Jan 11; Vol. 145 (1), pp. 110-121. Date of Electronic Publication: 2022 Dec 27.

Taming Radical Pairs in the Crystalline Solid State: Discovery and Total Synthesis of Psychotriadine.

Autor: Dotson JJ; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Liepuoniute I; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Bachman JL; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Hipwell VM; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Khan SI; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Houk KN; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Garg NK; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Garcia-Garibay MA; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2021 Mar 17; Vol. 143 (10), pp. 4043-4054. Date of Electronic Publication: 2021 Mar 08.

Scalable Synthesis of Vicinal Quaternary Stereocenters via the Solid-State Photodecarbonylation of a Crystalline Hexasubstituted Ketone.

Autor: Chang TY; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States., Dotson JJ; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States., Garcia-Garibay MA; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States.

Publikováno v: Organic letters [Org Lett] 2020 Nov 20; Vol. 22 (22), pp. 8855-8859. Date of Electronic Publication: 2020 Oct 29.

Taming Radical Pairs in Nanocrystalline Ketones: Photochemical Synthesis of Compounds with Vicinal Stereogenic All-Carbon Quaternary Centers.

Autor: Dotson JJ; Department of Chemistry and Biochemistry , University of California , Los Angeles , California 90095 , United States., Perez-Estrada S; Department of Chemistry and Biochemistry , University of California , Los Angeles , California 90095 , United States., Garcia-Garibay MA; Department of Chemistry and Biochemistry , University of California , Los Angeles , California 90095 , United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2018 Jul 11; Vol. 140 (27), pp. 8359-8371. Date of Electronic Publication: 2018 Jun 26.