Zobrazeno 1 - 10
of 12 042
pro vyhledávání: '"Dose-escalation"'
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-4 (2024)
Abstract Introduction Cetuximab, used to treat head and neck squamous cell carcinoma and metastatic colorectal cancer, can cause severe infusion reactions. Case presentation We report an 87-year-old East Asian woman with stage IV ileocecal signet rin
Externí odkaz:
https://doaj.org/article/a2092617c4d74373936b548acf97c8d6
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-6 (2024)
Abstract Introduction Anaplastic meningiomas, categorized as WHO grade 3 tumors, are rare and highly aggressive, accounting for 1-2% of all meningioma cases. Despite aggressive treatment, including surgery and Radiation, they exhibit a high recurrenc
Externí odkaz:
https://doaj.org/article/91f8975323404e72bedeb4a7f6388d9e
Autor:
Xiao-Han Zhao, Wen-Cheng Zhang, Xin Wang, Jun-Qiang Chen, Yuan-Ji Xu, Kuai-Le Zhao, Wei Huang, Pu-Dong Qian, Ya-Tian Liu, Xiao-Lin Ge, Xiao-Jie Xia, Chen-Gang Weng, Chun-Yue Gai, He-Song Wang, Hong-Mei Gao, Wen-Bin Shen, Shu-Chai Zhu
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Cervical and upper thoracic esophageal cancer (ESCA) presents treatment challenges due to limited clinical evidence. This multi-center study (ChC&UES) explores radical radio(chemo)therapy efficacy and safety, especially focusing o
Externí odkaz:
https://doaj.org/article/2b58d338d650478888964fe8000f1517
Autor:
Eugenia Veronica Di Brizzi, Stefano Caccavale, Roberta Di Caprio, Francesco Cusano, Rocco De Pasquale, Valeria Falcomatà, Caterina Foti, Claudia Giofrè, Emanuela Gubinelli, Giampiero Mazzocchetti, Massimiliano Nicolini, Giovanni Palazzo, Leonardo Pescitelli, Rosa Valentina Puca, Oriele Sarno, Anna Balato
Publikováno v:
Dermatology Practical & Conceptual, Vol 14, Iss 4 (2024)
Introduction: Tildrakizumab, a humanized monoclonal antibody targeting the p19 subunit of interleukin-23 (IL-23), has shown promise in the management of moderate-to-severe plaque psoriasis, offering potential improvements in clinical outcomes and qua
Externí odkaz:
https://doaj.org/article/261d266f4036428bb09dbbf60f883780
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 32, Iss , Pp 100645- (2024)
Focal boost to intra-prostatic lesions (IPLs) in radiotherapy could enhance treatment efficacy. Brachytherapy (BT), delivering highly conformal dose with sharp dose gradients emerges as a potentially optimal approach for precise dose escalation to IP
Externí odkaz:
https://doaj.org/article/5e1a33982a7a4da2a07a8c0a1d36dd2a
Autor:
Arno C. Hessels, Sabine Visser, Stefan Both, Erik W. Korevaar, Johannes A. Langendijk, Robin Wijsman
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 31, Iss , Pp 100616- (2024)
In non-small-cell lung cancer (NSCLC), improving local control through radiotherapy dose escalation might improve survival. However, a photon-based RCT showed increased organ at risk dose exposure and worse overall survival in the dose escalation arm
Externí odkaz:
https://doaj.org/article/41b3fef774014591bffa21599848c34d
Autor:
Sebastian H. Maier, Stephan Schönecker, Vasiliki Anagnostatou, Sylvia Garny, Alexander Nitschmann, Daniel F. Fleischmann, Marcel Büttner, David Kaul, Detlef Imhoff, Emmanouil Fokas, Clemens Seidel, Peter Hau, Oliver Kölbl, Ilinca Popp, Anca-Ligia Grosu, Jan Haussmann, Wilfried Budach, Eren Celik, Klaus-Henning Kahl, Elgin Hoffmann, Ghazaleh Tabatabai, Frank Paulsen, Adrien Holzgreve, Nathalie L. Albert, Ulrich Mansmann, Stefanie Corradini, Claus Belka, Maximilian Niyazi, Raphael Bodensohn
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 47, Iss , Pp 100790- (2024)
Background: The PRIDE trial (NOA-28; ARO-2024-01; AG-NRO-06; NCT05871021) is designed to determine whether a dose escalation with 75.0 Gy in 30 fractions can enhance the median overall survival (OS) in patients with methylguanine methyltransferase (M
Externí odkaz:
https://doaj.org/article/e593b5076b1b4d3582a15845aa79e307
Autor:
Christopher Shi, Brian De, Hop S. Tran Cao, Suyu Liu, Marcus A. Florez, Ramez Kouzy, Adam J. Grippin, Matthew H. G. Katz, Ching‐Wei D. Tzeng, Naruhiko Ikoma, Michael P. Kim, Sunyoung Lee, Jason Willis, Sonal S. Noticewala, Bruce D. Minsky, Grace L. Smith, Emma B. Holliday, Cullen M. Taniguchi, Albert C. Koong, Prajnan Das, Ethan B. Ludmir, Eugene J. Koay
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Introduction With locally advanced pancreatic cancer (LAPC), uncontrolled local tumor growth frequently leads to mortality. Advancements in radiotherapy (RT) techniques have enabled conformal delivery of escalated‐dose RT (EDR), which may
Externí odkaz:
https://doaj.org/article/0557a6dc1068470ebd1f0ab16f0569c2
Autor:
Sui wai Ling, Astrid A. M. van der Veldt, Mark Konijnenberg, Marcel Segbers, Eline Hooijman, Frank Bruchertseifer, Alfred Morgenstern, Erik de Blois, Tessa Brabander
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Life expectancy of patients with metastatic castration-resistant prostate cancer (mCRPC) is still limited despite several systemic treatments. Within five years after diagnosis of primary prostate cancer, 10–20% of the patients
Externí odkaz:
https://doaj.org/article/7895c2af2d0a42f0969b2758f379db83
Autor:
Melissa P. Wasserstein, Robin Lachmann, Carla Hollak, Antonio Barbato, Renata C. Gallagher, Roberto Giugliani, Norberto Bernardo Guelbert, Julia B. Hennermann, Takayuki Ikezoe, Olivier Lidove, Paulina Mabe, Eugen Mengel, Maurizio Scarpa, Ebubekir Senates, Michel Tchan, Jesus Villarrubia, Beth L. Thurberg, Abhimanyu Yarramaneni, Nicole M. Armstrong, Yong Kim, Monica Kumar
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Background Olipudase alfa is a recombinant human acid sphingomyelinase enzyme replacement therapy for non-central-nervous-system manifestations of acid sphingomyelinase deficiency (ASMD). The ASCEND randomized placebo-controlled trial in adu
Externí odkaz:
https://doaj.org/article/7737861ecbf54c38965ac8ebac64bc3c