CD44 expression profile varies according to maturational subtypes and molecular profiles of pediatric T-cell lymphoblastic leukemia

Autor: Francianne Gomes Andrade, Elda Pereira Noronha, Eugênia Terra-Granado, Marques Lvc, Dos Santos-Bueno Fv, Maria S. Pombo-de-Oliveira, Mansur Mb

Publikováno v: Frontiers in Oncology
Frontiers in Oncology, Vol 8 (2018)

CD44 is a glycoprotein expressed in leucocytes and a marker of leukemia-initiating cells, being shown to be important in the pathogenesis of T cell acute lymphoblastic leukemia (T-ALL). In this study, we have (i) identified the aberrant antigenic pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f7f49e03fbdfbe8187cc03b7f0179d
https://ora.ox.ac.uk/objects/uuid:e92804f8-fc8b-45b1-901b-53a4dfcf06b8

Pediatric Acute Promyelocytic Leukemia: Epidemiology, Molecular Features, and Importance of GST-Theta 1 in Chemotherapy Response and Outcome.

Autor: Andrade FG; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Feliciano SVM; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Sardou-Cezar I; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Brisson GD; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Dos Santos-Bueno FV; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Vianna DT; Laboratory of Molecular Biology, Bone Marrow Transplantation Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Marques LVC; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Terra-Granado E; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Zalcberg I; Laboratory of Molecular Biology, Bone Marrow Transplantation Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Santos MO; Surveillance and Prevention, Instituto Nacional de Cancer, Rio de Janeiro, Brazil., Costa JT; Department of Pediatric Hematology-Oncology, Hospital Martagão Gesteira, Salvador, Brazil., Noronha EP; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Thuler LCS; Clinical Research Department, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Wiemels JL; Center for Genetic Epidemiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Pombo-de-Oliveira MS; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.

Publikováno v: Frontiers in oncology [Front Oncol] 2021 Mar 19; Vol. 11, pp. 642744. Date of Electronic Publication: 2021 Mar 19 (Print Publication: 2021).

Childhood Myeloid Neoplasms With PTPN11 Mutations in Brazil.

Autor: Dos Santos-Bueno FV; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil., Andrade FG; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil., Sardou-Cezar I; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil., Mendes-de-Almeida DP; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil; Division of Hematology, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (INI/Fiocruz), Rio de Janeiro, Brazil., Chung-Filho AA; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil., Brisson GD; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil., Terra-Granado E; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil., Noronha EP; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil., Santos Thuler LC; Division of Clinical Research, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil., Pombo-de-Oliveira MS; Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil. Electronic address: mpombo@inca.gov.br.

Publikováno v: Clinical lymphoma, myeloma & leukemia [Clin Lymphoma Myeloma Leuk] 2020 Aug; Vol. 20 (8), pp. e496-e505. Date of Electronic Publication: 2020 Apr 20.

GATA2 mutation in long stand Mycobacterium kansasii infection, myelodysplasia and MonoMAC syndrome: a case-report.

Autor: Mendes-de-Almeida DP; Division of Hematology, Evandro Chagas National Institute of Infectology, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.; Pediatric Hematology-Oncology Program, 6thfloor, Research Center, Instituto Nacional de Câncer-INCa, Rua André Cavalcanti, 37, Rio de Janeiro, Zip code: 20231- 050, Brazil., Andrade FG; Pediatric Hematology-Oncology Program, 6thfloor, Research Center, Instituto Nacional de Câncer-INCa, Rua André Cavalcanti, 37, Rio de Janeiro, Zip code: 20231- 050, Brazil., Borges G; Department of Internal Medicine, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, Brazil., Dos Santos-Bueno FV; Pediatric Hematology-Oncology Program, 6thfloor, Research Center, Instituto Nacional de Câncer-INCa, Rua André Cavalcanti, 37, Rio de Janeiro, Zip code: 20231- 050, Brazil., Vieira IF; Infectious Diseases Department, Hospital dos Servidores do Estado, Rio de Janeiro, Brazil., da Rocha LKMDS; Division of Hematology, Oncologia D'Or, Rio de Janeiro, Brazil., Mendes-da-Cruz DA; Laboratory on Thymus Research, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.; Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil., Zancopé-Oliveira RM; Laboratory of Mycology, Evandro Chagas National Institute of Infectology, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Calado RT; Department of Internal Medicine, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, Brazil., Pombo-de-Oliveira MS; Pediatric Hematology-Oncology Program, 6thfloor, Research Center, Instituto Nacional de Câncer-INCa, Rua André Cavalcanti, 37, Rio de Janeiro, Zip code: 20231- 050, Brazil. mpombo@inca.gov.br.

Publikováno v: BMC medical genetics [BMC Med Genet] 2019 Apr 29; Vol. 20 (1), pp. 64. Date of Electronic Publication: 2019 Apr 29.

EPHX1 rs1051740 T>C (Tyr113His) is strongly associated with acute myeloid leukemia and KMT2A rearrangements in early age.

Autor: Brisson GD; Pediatric Hematology-Oncology Research Program, Research Center, Instituto Nacional de Câncer (INCA), Rua André Cavalcanti 37, Rio de Janeiro, RJ, Brazil., de Almeida Lopes B; Pediatric Hematology-Oncology Research Program, Research Center, Instituto Nacional de Câncer (INCA), Rua André Cavalcanti 37, Rio de Janeiro, RJ, Brazil., Andrade FG; Pediatric Hematology-Oncology Research Program, Research Center, Instituto Nacional de Câncer (INCA), Rua André Cavalcanti 37, Rio de Janeiro, RJ, Brazil., Dos Santos Bueno FV; Pediatric Hematology-Oncology Research Program, Research Center, Instituto Nacional de Câncer (INCA), Rua André Cavalcanti 37, Rio de Janeiro, RJ, Brazil., Sardou-Cezar I; Pediatric Hematology-Oncology Research Program, Research Center, Instituto Nacional de Câncer (INCA), Rua André Cavalcanti 37, Rio de Janeiro, RJ, Brazil., de Aguiar Gonçalves BA; Pediatric Hematology-Oncology Research Program, Research Center, Instituto Nacional de Câncer (INCA), Rua André Cavalcanti 37, Rio de Janeiro, RJ, Brazil., Terra-Granado E; Pediatric Hematology-Oncology Research Program, Research Center, Instituto Nacional de Câncer (INCA), Rua André Cavalcanti 37, Rio de Janeiro, RJ, Brazil., Paraguassú-Braga FH; Centro de Processamento e Armazenamento Celular, Banco de Sangue de Cordão Umbilical, Centro de Transplante e Terapia Celular, Instituto Nacional de Câncer (INCA), Praça da Cruz Vermelha 23, Rio de Janeiro, RJ, Brazil., Pombo-de-Oliveira MS; Pediatric Hematology-Oncology Research Program, Research Center, Instituto Nacional de Câncer (INCA), Rua André Cavalcanti 37, Rio de Janeiro, RJ, Brazil. mpombo@inca.gov.br.

Publikováno v: Archives of toxicology [Arch Toxicol] 2018 Jun; Vol. 92 (6), pp. 2001-2012. Date of Electronic Publication: 2018 Mar 31.