Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation

Autor: Peeters, Michiel, Barrera Jiménez, Ana Alejandra, Matsunami, Kensaku, Ghijs, Michael, dos Santos Schultz, Eduardo, Roudgar, Mina, Vigh, Tamas, Stauffer, Fanny, Nopens, Ingmar, De Beer, Thomas

Publikováno v: In International Journal of Pharmaceutics 25 January 2024 650

Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation

Autor: Barrera Jiménez, Ana Alejandra, Matsunami, Kensaku, Van Hauwermeiren, Daan, Peeters, Michiel, Stauffer, Fanny, dos Santos Schultz, Eduardo, Kumar, Ashish, De Beer, Thomas, Nopens, Ingmar

Publikováno v: In International Journal of Pharmaceutics 10 June 2023 640

Validation of model-based design of experiments for continuous wet granulation and drying

Autor: Matsunami, Kensaku, Vandeputte, Tuur, Barrera Jiménez, Ana Alejandra, Peeters, Michiel, Ghijs, Michael, Van Hauwermeiren, Daan, Stauffer, Fanny, dos Santos Schultz, Eduardo, Nopens, Ingmar, De Beer, Thomas

Publikováno v: In International Journal of Pharmaceutics October 2023

Guaranteed feasibility of optimal control problems with and without uncertainty

Autor: dos Santos Schultz, Eduardo

Publikováno v: Aachen : RWTH Aachen University, Aachener Verfahrenstechnik Series 20, 1 Online-Ressource : Illustrationen, Diagramme (2021). doi:10.18154/RWTH-2022-06743 = Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2021

Path constraints arise naturally in dynamic optimization within chemical and biological processes due to process safety, environmental regulations, or critical quality attributes. Thus, they must be satisfied which poses a substantial challenge becau

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