Toxicity of thimerosal in biological systems: Conformational changes in human hemoglobin, decrease of oxygen binding capacity, increase of protein glycation and amyloid's formation.

Autor: de Magalhães Silva M; Institute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil., de Araújo Dantas MD; Institute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil., da Silva Filho RC; Institute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil., Dos Santos Sales MV; Institute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil., de Almeida Xavier J; Institute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil., Leite ACR; Institute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil., Goulart MOF; Institute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil., Grillo LAM; Pharmacy Institute, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil., de Barros WA; Department of Chemistry, Federal University of Minas Gerais (UFMG), 31270-901 Belo Horizonte, Minas Gerais, Brazil., de Fátima Â; Department of Chemistry, Federal University of Minas Gerais (UFMG), 31270-901 Belo Horizonte, Minas Gerais, Brazil., Figueiredo IM; Institute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil., Santos JCC; Institute of Chemistry and Biotechnology, Federal University of Alagoas (UFAL), Campus A.C. Simões, 57072-900 Maceió, Alagoas, Brazil. Electronic address: josue@iqb.ufal.br.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2020 Jul 01; Vol. 154, pp. 661-671. Date of Electronic Publication: 2020 Mar 19.