Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dorys Lopez"'
Autor:
Michelle Weitz, J. R. Pfeiffer, Snehal Patel, Matthew Biancalana, Arda Pekis, Vignesh Kannan, Evandros Kaklamanos, Amanda Parker, Jesse E. Bucksot, José Rubio Romera, Ryan Alvin, Yuhan Zhang, Andrew T. Stefka, Dorys Lopez-Ramos, Joseph R. Peterson, Anuja K. Antony, Kathryn W. Zamora, Stefanie Woodard
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Surgery remains the primary treatment modality in the management of early-stage invasive breast cancer. Artificial intelligence (AI)-powered visualization platforms offer the compelling potential to aid surgeons in evaluating the tumor’s l
Externí odkaz:
https://doaj.org/article/675e3d432ddd48f5a5dec9a51655231b
Autor:
Christina A. Clarke, Breeana L. Mitchell, Girish Putcha, Emma Alme, Peter Bach, Jonathan P. Beer, Tomasz M. Beer, Michelle A. Beidelschies, Jody Hoyos, Eric Klein, Peter Kuhn, Nancy Krunic, Kathryn Lang, Jerry S. H. Lee, Dorys Lopez Ramos, David Morgenstern, Elissa Quinn, Victoria M. Raymond, Wendy S. Rubinstein, Stephanie A. Sanchez, Ryan Serra, Mark Stewart, Lauren C. Leiman
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 9, Pp n/a-n/a (2024)
Abstract In the United States, 2.0 million new cancer cases and around 600,000 cancer deaths are estimated to occur in 2024. Early detection gives cancer patients the best chance for treatment success. Currently, cancer screening in the general popul
Externí odkaz:
https://doaj.org/article/c657a0e63df242488b58bf90dd7f4466
Autor:
Joseph R. Peterson, John A. Cole, John R. Pfeiffer, Gregory H. Norris, Yuhan Zhang, Dorys Lopez-Ramos, Tushar Pandey, Matthew Biancalana, Hope R. Esslinger, Anuja K. Antony, Vinita Takiar
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Generalizable population-based studies are unable to account for individual tumor heterogeneity that contributes to variability in a patient’s response to physician-chosen therapy. Although molecular characterization of tumors h
Externí odkaz:
https://doaj.org/article/12eef036e02a49309bc1c05dd6fdb0b4
Autor:
Daniel Cook, Matthew Biancalana, Nicole Liadis, Dorys Lopez Ramos, Yuhan Zhang, Snehal Patel, Joseph R. Peterson, John R. Pfeiffer, John A. Cole, Anuja K. Antony
Publikováno v:
Frontiers in Artificial Intelligence, Vol 6 (2023)
BackgroundImmuno-oncology (IO) therapies targeting the PD-1/PD-L1 axis, such as immune checkpoint inhibitor (ICI) antibodies, have emerged as promising treatments for early-stage breast cancer (ESBC). Despite immunotherapy's clinical significance, th
Externí odkaz:
https://doaj.org/article/be8738fdce2d43f1bb22f5d1661eba9f
Autor:
Janne Ruotsalainen, Dorys Lopez‐Ramos, Meri Rogava, Naveen Shridhar, Nicole Glodde, Evelyn Gaffal, Michael Hölzel, Tobias Bald, Thomas Tüting
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 4, Pp n/a-n/a (2021)
Abstract Objectives Type I interferons are evolutionally conserved cytokines, with broad antimicrobial and immunoregulatory functions. Despite well‐characterised role in spontaneous cancer immunosurveillance, the function of type I IFNs in cancer i
Externí odkaz:
https://doaj.org/article/4928115443f740c09ac016ffe4ccb669
Autor:
Thomas Tüting, Michael Hölzel, Göran Jönsson, Andreas Limmer, Ulrich Kalinke, Rene Tolba, Julia Steitz, Evelyn Gaffal, Philipp Jansen, Nicole Glodde, Marcel Renn, Dorys Lopez-Ramos, Jennifer Landsberg, Tobias Bald
XLS file 28K, List of top 50 interferon alpha induced gene across five humane melanoma cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7700b2b2680b4a7a8b8361e176a2d67
https://doi.org/10.1158/2159-8290.22530351.v1
https://doi.org/10.1158/2159-8290.22530351.v1
Autor:
Thomas Tüting, Michael Hölzel, Göran Jönsson, Andreas Limmer, Ulrich Kalinke, Rene Tolba, Julia Steitz, Evelyn Gaffal, Philipp Jansen, Nicole Glodde, Marcel Renn, Dorys Lopez-Ramos, Jennifer Landsberg, Tobias Bald
PDF file 309K, Results of repeated dose acute toxicity study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e7f4c859faea8eca1c2cb1345429c8
https://doi.org/10.1158/2159-8290.22530354
https://doi.org/10.1158/2159-8290.22530354
Autor:
Michael Hölzel, Thomas Tüting, Paul C. Tumeh, Mark J. Smyth, Antoni Ribas, Richard A. Scolyer, Jason Madore, Georgina V. Long, Dirk Schadendorf, Waldemar Kolanus, Thomas Quast, Hubert Schorle, Daniel Nettersheim, Shin Foong Ngiow, Arabella Young, Dorys Lopez-Ramos, Nicole Glodde, Tobias Bald, Bartomeu Bibiloni Ramis, Jonathan L. Schmid-Burgk, Jennifer Landsberg, Julia Reinhardt
Evolution of tumor cell phenotypes promotes heterogeneity and therapy resistance. Here we found that induction of CD73, the enzyme that generates immunosuppressive adenosine, is linked to melanoma phenotype switching. Activating MAPK mutations and gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0752b259a7af845eee3bf6fb8ec537f1
https://doi.org/10.1158/0008-5472.c.6508868
https://doi.org/10.1158/0008-5472.c.6508868
Autor:
Michael Hölzel, Thomas Tüting, Paul C. Tumeh, Mark J. Smyth, Antoni Ribas, Richard A. Scolyer, Jason Madore, Georgina V. Long, Dirk Schadendorf, Waldemar Kolanus, Thomas Quast, Hubert Schorle, Daniel Nettersheim, Shin Foong Ngiow, Arabella Young, Dorys Lopez-Ramos, Nicole Glodde, Tobias Bald, Bartomeu Bibiloni Ramis, Jonathan L. Schmid-Burgk, Jennifer Landsberg, Julia Reinhardt
Supplemental Table S7. Hallmark gene sets up in ACT-treated relapse (R) HCmel3 melanomas versus early during treatment (EDT) HCmel3 melanomas (GSEA results).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e355971a335495ae4e07924aa0ed41
https://doi.org/10.1158/0008-5472.22414013.v1
https://doi.org/10.1158/0008-5472.22414013.v1
Autor:
Michael Hölzel, Thomas Tüting, Paul C. Tumeh, Mark J. Smyth, Antoni Ribas, Richard A. Scolyer, Jason Madore, Georgina V. Long, Dirk Schadendorf, Waldemar Kolanus, Thomas Quast, Hubert Schorle, Daniel Nettersheim, Shin Foong Ngiow, Arabella Young, Dorys Lopez-Ramos, Nicole Glodde, Tobias Bald, Bartomeu Bibiloni Ramis, Jonathan L. Schmid-Burgk, Jennifer Landsberg, Julia Reinhardt
Supplemental Table S1. DNA oligos used in this study Supplemental Table S2. Characteristics of patients with primary melanomas and cutaneous melanoma metastasis (Bonn cohorts). Supplemental Table S4. List of transcription factors binding in NT5E base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6f05a4b8dac755c30aa3dd0d04d060
https://doi.org/10.1158/0008-5472.22414010.v1
https://doi.org/10.1158/0008-5472.22414010.v1