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of 8
pro vyhledávání: '"Doru V Chirieac"'
Autor:
Ursula Andreo, Liang Guo, Doru V Chirieac, Ana C Tuyama, Emilie Montenont, Jeffrey L Brodsky, Edward A Fisher
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57590 (2013)
Both in humans and animal models, an acute increase in plasma insulin levels, typically following meals, leads to transient depression of hepatic secretion of very low density lipoproteins (VLDL). One contributing mechanism for the decrease in VLDL s
Externí odkaz:
https://doaj.org/article/a6c2c43a04d24deea770a57e280fcd1c
Publikováno v:
Biochemical and Biophysical Research Communications. 297:134-137
Insulin inhibits hepatic very low density lipoprotein (VLDL) apo B secretion in rats. Current studies test whether the insulin effect is LDL receptor-mediated by examining the effect of insulin on VLDL apo B secretion in hepatocytes derived from Ldlr
Autor:
Ana C. Tuyama, Jeffrey L. Brodsky, Ursula Andreo, Liang Guo, Emilie Montenont, Edward A. Fisher, Doru V. Chirieac
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e57590 (2013)
PLoS ONE, Vol 8, Iss 3, p e57590 (2013)
Both in humans and animal models, an acute increase in plasma insulin levels, typically following meals, leads to transient depression of hepatic secretion of very low density lipoproteins (VLDL). One contributing mechanism for the decrease in VLDL s
Autor:
Thomas A. Pearson, Doru V Chirieac
Publikováno v:
New England Journal of Medicine. 346:1093-1095
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 291(3)
Insulin regulates hepatic VLDL production by activation of phosphatidylinositide 3-kinase (PI3-kinase) which decreases apo B available for lipid assembly. The current study evaluated the dependence of the VLDL apolipoprotein B (apo B) pathway on PI3-
Autor:
Mark P. Sowden, Joanne Cianci, Jenny D. Jokinen, Charles E. Sparks, Doru V. Chirieac, Janet D. Sparks, Chad A. Galloway, Heidi L. Collins
Publikováno v:
The Biochemical journal. 395(2)
We have previously reported a positive correlation between the expression of BHMT (betaine–homocysteine S-methyltransferase) and ApoB (apolipoprotein B) in rat hepatoma McA (McArdle RH-7777) cells [Sowden, Collins, Smith, Garrow, Sparks and Sparks
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 287(1)
Triglyceride-rich lipoprotein (TRL) production was studied in Zucker diabetic fatty (ZDF) rats, a model of insulin-resistant type 2 diabetes progression. TRL production was measured in vivo by blocking catabolism with Triton WR-1339. Ten-week ZDF rat
Autor:
Joanne Cianci, Janet D. Sparks, James P. Corsetti, Lucian R. Chirieac, Charles E. Sparks, Doru V. Chirieac
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 279(5)
The current study assessed in vivo the effect of insulin on triglyceride-rich lipoprotein (TRL) production by rat liver. Hepatic triglyceride and apolipoprotein B (apoB) production were measured in anesthetized, fasted rats injected intravenously wit