Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dorothy M. Keefe"'
Autor:
Kate R. Secombe, Imogen A. Ball, Anthony D. Wignall, Emma Bateman, Dorothy M. Keefe, Joanne M. Bowen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 30, Iss , Pp 100806- (2022)
Background: Neratinib is a pan-ErbB tyrosine kinase inhibitor used for extended adjuvant treatment of HER2-positive breast cancer. Diarrhea is the main adverse event associated with neratinib treatment. We aimed here to determine whether antibiotic-i
Externí odkaz:
https://doaj.org/article/7e1901768b1942179f5a95af6966271e
Autor:
Samantha K. Korver, Joanne M. Bowen, Rachel J. Gibson, Imogen A. Ball, Kate R. Secombe, Taylor J. Wain, Richard M. Logan, Jonathan Tuke, Kelly R. Mead, Alison M. Richards, Christos S. Karapetis, Dorothy M. Keefe, Janet K. Coller
Publikováno v:
Cancer Chemotherapy and Pharmacology. 91:507-521
Purpose Adverse effects following fluoropyrimidine-based chemotherapy regimens are common. However, there are no current accepted diagnostic markers for prediction prior to treatment, and the underlying mechanisms remain unclear. This study aimed to
Autor:
Kate R, Secombe, Imogen A, Ball, Joseph, Shirren, Anthony D, Wignall, Dorothy M, Keefe, Joanne M, Bowen
Publikováno v:
Breast cancer (Tokyo, Japan). 28(1)
Neratinib is a potent irreversible pan-ErbB tyrosine kinase inhibitor, approved by the FDA for extended adjuvant treatment of HER2-positive breast cancer. Diarrhea is the most frequently observed adverse event with tyrosine kinase inhibitor therapy.
Autor:
Bronwen J, Mayo, Kate R, Secombe, Anthony D, Wignall, Emma, Bateman, Daniel, Thorpe, Claudio, Pietra, Dorothy M, Keefe, Joanne M, Bowen
Publikováno v:
Cancer chemotherapy and pharmacology. 85(4)
Lapatinib is a small molecule tyrosine kinase inhibitor used to treat breast cancer, often in combination with chemotherapy. Diarrhoea commonly occurs in up to 78% of patients undertaking lapatinib treatment. The mechanism of this diarrhoea is curren
Autor:
Rajesh V, Lalla, Michael T, Brennan, Sharon M, Gordon, Stephen T, Sonis, David I, Rosenthal, Dorothy M, Keefe
Publikováno v:
Journal of the National Cancer Institute. Monographs. 2019(53)
Oral mucositis is a common side-effect associated with conventional cancer therapy and has also recently been reported in association with newly emerging cancer therapies. It is characterized as an inflammation of the oral mucous membranes accompanie
Autor:
Stephen T. Sonis, Dorothy M. Keefe
The contents of this book will be organized into three sections. The first section defines the scope, impact and behaviour of cancer regimen-related toxicities and frames the issue of balancing treatment success and physiological cost. In the second
Autor:
Stephen T. Sonis, Dorothy M. Keefe
Publikováno v:
Pathobiology of Cancer Regimen-Related Toxicities ISBN: 9781461454373
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49e81cec13ba611ea1d35a804b85cbd5
https://doi.org/10.1007/978-1-4614-5438-0_15
https://doi.org/10.1007/978-1-4614-5438-0_15
Publikováno v:
Pathobiology of Cancer Regimen-Related Toxicities ISBN: 9781461454373
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e40655310837f403f59f96eb8cf9abad
https://doi.org/10.1007/978-1-4614-5438-0_7
https://doi.org/10.1007/978-1-4614-5438-0_7
Autor:
Noor, Al-Dasooqi, Joanne M, Bowen, Rachel J, Gibson, Richard M, Logan, Andrea M, Stringer, Dorothy M, Keefe
Publikováno v:
International journal of experimental pathology. 92(5)
Chemotherapy-induced mucositis is characterized by damage of mucous membranes throughout the alimentary tract (AT). Extracellular matrix (ECM) components play a vital role in maintaining mucosal barrier integrity by regulating cellular apoptosis, pro
Autor:
Linda S, Elting, Dorothy M, Keefe, Stephen T, Sonis, Adam S, Garden, F K L, Spijkervet, Andrei, Barasch, Roy B, Tishler, Thomas P, Canty, Mahesh K, Kudrimoti, Montserrat, Vera-Llonch, M, Vera-Llonch
Publikováno v:
Cancer, 113(10), 2704-2713. Wiley
BACKGROUND. I-lie risk, severity, and patient-reported outcomes of radiation-induced mucositis among head and neck cancer patients were prospectively estimated.METHODS. A validated, patient-reported questionnaire (OMDQ), the FACT quality of life (QOL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d552126b3a6edba8f31539432e7ea3
https://research.rug.nl/en/publications/bf3ae1cc-432b-42fa-99e8-7f5341a5de29
https://research.rug.nl/en/publications/bf3ae1cc-432b-42fa-99e8-7f5341a5de29