Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Dorothy M Supp"'
Autor:
Jennifer M Hahn, Kelly A Combs, Christopher M Lloyd, Kevin L McFarland, Steven T Boyce, Dorothy M Supp
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213325 (2019)
Engineered skin substitutes (ESS), prepared using primary human fibroblasts and keratinocytes with a biopolymer scaffold, were shown to provide stable closure of excised burns, but relatively little is known about innervation of ESS after grafting. T
Externí odkaz:
https://doaj.org/article/38c54458966343c997cba9612767d5e3
Autor:
Danielle M DeBruler, Jacob C Zbinden, Molly E Baumann, Britani N Blackstone, Megan M Malara, J Kevin Bailey, Dorothy M Supp, Heather M Powell
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197558 (2018)
Pressure garment therapy is often prescribed to improve scar properties following full-thickness burn injuries. Pressure garment therapy is generally recommended for long periods of time following injury (1-2 years), though it is plagued by extremely
Externí odkaz:
https://doaj.org/article/38f44dc9e96640c88df51b267ffa05ac
Autor:
Julie M Lander, Dorothy M Supp, Hua He, Lisa J Martin, Xiaoting Chen, Matthew T Weirauch, Steven T Boyce, Raphael Kopan
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184500 (2017)
To identify putative gene regulatory regions that respond to epidermal injury, we mapped chromatin dynamics in a stratified human epidermis during barrier maturation and disruption. Engineered skin substitutes (ESS) cultured at the air-liquid interfa
Externí odkaz:
https://doaj.org/article/54d61c4324844856b7cf9f81c01f613f
Autor:
Stanley B. DeVore, Matthew Schuetz, Lauren Alvey, Henry Lujan, David E. Ochayon, Lindsey Williams, Wan Chi Chang, Alyssa Filuta, Brandy Ruff, Arjun Kothari, Jennifer M. Hahn, Eric Brandt, Latha Satish, Krishna Roskin, Andrew B. Herr, Jocelyn M. Biagini, Lisa J. Martin, Deniz Cagdas, Sevgi Keles, Joshua D. Milner, Dorothy M. Supp, Gurjit K. Khurana Hershey
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114589- (2024)
Summary: Caspase recruitment domain family member 14 (CARD14) and its variants are associated with both atopic dermatitis (AD) and psoriasis, but their mechanistic impact on skin barrier homeostasis is largely unknown. CARD14 is known to signal via N
Externí odkaz:
https://doaj.org/article/93643c0fb9c04c9683a5cbbebc4dcd2e
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65664 (2013)
Generation of skin appendages in engineered skin substitutes has been limited by lack of trichogenic potency in cultured postnatal cells. To investigate the feasibility and the limitation of hair regeneration, engineered skin substitutes were prepare
Externí odkaz:
https://doaj.org/article/e62437f2037748f89138c08cb03c87cf
Publikováno v:
Journal of Burn Care & Research. 44:535-545
Burn scars, and in particular, hypertrophic scars, are a challenging yet common outcome for survivors of burn injuries. In 2021, the American Burn Association brought together experts in burn care and research to discuss critical topics related to bu
Autor:
Charles C. Caldwell, Christian B. Bergmann, Holly S. Goetzman, Bruce D. Hammock, Dorothy M. Supp, Falk Gogolla, Debin Wan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific reports, vol 11, iss 1
Scientific Reports
Scientific reports, vol 11, iss 1
Oxylipins modulate the behavior of immune cells in inflammation. Soluble epoxide hydrolase (sEH) converts anti-inflammatory epoxyeicosatrienoic acid (EET) to dihydroxyeicosatrienoic acid (DHET). An sEH-inhibitor, TPPU, has been demonstrated to amelio
Autor:
Heather M. Powell, Megan M. Malara, Britani N. Blackstone, Molly E. Baumann, Dorothy M. Supp, J. Kevin Bailey
Publikováno v:
Tissue Engineering Part A. 26:1138-1146
For patients with large, full-thickness burn wounds, sufficient donor sites for autografting are not available, and thus, alternate strategies must be used to close these wounds. Cultured epithelial autografts (CEAs) can aid in closing these wounds b
Autor:
Christian B. Bergmann, Cindy B. McReynolds, Debin Wan, Nalin Singh, Holly Goetzman, Charles C. Caldwell, Dorothy M. Supp, Bruce D. Hammock
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 13
Fatty acid composition in the Western diet has shifted from saturated to polyunsaturated fatty acids (PUFAs), and specifically to linoleic acid (LA, 18:2), which has gradually increased in the diet over the past 50 y to become the most abundant dieta
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101172-(2022)
Summary: Four types of primary cells—dermal fibroblasts, dermal microvascular endothelial cells, epidermal keratinocytes, and epidermal melanocytes—can be isolated simultaneously from a single human skin sample, without the use of xenogeneic muri