Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Dorothy K.L. Xing"'
Autor:
Chun-Ting Yuen, George Buckle, Catpagavalli Asokanathan, Adrian Bristow, Dorothy K.L. Xing, Simon Tanley, Sharon Tierney, Kevin Markey, Ami Day, Christina Ball
Publikováno v:
Analytical biochemistry.
ADP-ribosyltransferase activities have been observed in many prokaryotic and eukaryotic species and viruses and are involved in many cellular processes, including cell signalling, DNA repair, gene regulation and apoptosis. In a number of bacterial to
Autor:
Dorothy K.L. Xing, Alex, Catpagavalli Asokanathan, Kevin Markey, ra Douglas-Bardsley, Chun-Ting Yuen, Peter Rigsby
Publikováno v:
Journal of Vaccines & Vaccination.
Pertussis (whooping cough) vaccines play an essential role in immunisation programmes worldwide and the histamine sensitisation test (HIST) is currently the official batch-release test for acellular pertussis containing combination vaccines. HIST, be
Autor:
R.E. Gaines Das, Catpagavalli Asokanathan, Alexandra Douglas-Bardsley, Dorothy K.L. Xing, Penny Newland, Michael J. Corbel
Publikováno v:
Biologicals. 38:644-651
Whole cell pertussis vaccine is still widely used in many countries. An International Standard is needed for its potency control. The Third International Standard for Pertussis Vaccine was prepared about 40 years ago and its replacement was recommend
Autor:
John B. Robbins, A. Morris, Bruce D. Meade, Nicole Guiso, Stephen W. Hildreth, ChrisAnna M. Mink, Nancy E. Messonnier, Dorothy K.L. Xing, Drusilla L. Burns, L. Han, Kathryn M. Edwards, Maria Lucia Tondella, L. Hueston, James D. Cherry, Conrad P. Quinn, Erik L. Hewlett, M. Powell, C. H. Wirsing Von König, Jan Poolman, F. Lynn, George M. Carlone, Anna Giammanco
Publikováno v:
Vaccine
Vaccine, vol 27, iss 6
Vaccine, vol 27, iss 6
An international meeting on Bordetella pertussis assay standardization and harmonization was held at the Centers for Disease Control and Prevention (CDC), Atlanta, GA, 19-20 July 2007. The goal of the meeting was to harmonize the immunoassays used fo
Publikováno v:
Vaccine. 26:3960-3968
New acellular pertussis vaccines have recently been developed in China and India. In this context, potency testing and potential improvements of the protective animal models with inclusion of a reference material were recognized as critical issues in
Autor:
Dorothy K.L. Xing, Yoshinobu Horiuchi, R. Dobbelaer, Rose Gaines Das, Michael J. Corbel, Dianliang Lei
Publikováno v:
Vaccine. 26:1913-1921
Summary This report reflects the discussion and conclusions of a WHO group of experts from National Regulatory Authorities (NRAs), National Control Laboratories (NCLs), vaccine industries and other relevant institutions involved in standardization an
Publikováno v:
Vaccine. 25:2749-2757
This report reflects the discussion and conclusions of a WHO group of experts from national regulatory authorities, national control laboratories, vaccine industry and other relevant institutions involved in standardisation and control of acellular p
Autor:
Imogen Kelso, Dorothy K.L. Xing, Jun X Wheeler, Catpagavalli Asokanathan, Barbara Bolgiano, Chun-Ting Yuen, Qiushui He, Frits R Mooi, Kevin Markey, Dorota Kmiec
Publikováno v:
Journal of Clinical & Experimental Pathology.
Whooping cough caused by Bordetella pertussis is a serious disease especially for infants and young children. Detoxified pertussis toxin is a key component of vaccines used in campaigns worldwide for the prevention of the disease. A biochemical assay
Autor:
Dorothy K.L. Xing, Sheena R. Gomez, Chun-Ting Yuen, John G. Coote, Roger Parton, Michael J. Corbel
Publikováno v:
Analytical Biochemistry. 356:244-253
Pertussis toxin (PTx) is a major virulence factor produced by Bordetella pertussis and, in its detoxified form PTd, is an important component of pertussis vaccines. The in vivo histamine sensitization test (HIST) is currently used for the safety test
Autor:
Glyn Stacey, Dorothy K.L. Xing, Roland A. Fleck, Sandra Prior, Peter Rigsby, Margaret L. Gillett, Michael J. Corbel
Publikováno v:
Vaccine. 24:4794-4803
Recombinant, genetically-detoxified adenylate cyclase toxin (CyaA) constructs from Bordetella pertussis have been developed as potential antigen delivery systems and as promising antigen candidates for inclusion in acellular pertussis vaccines. The m