Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dorothy J. You"'
Autor:
Dorothy J. You, Bria M. Gorman, Noah Goshi, Nicholas R. Hum, Aimy Sebastian, Yong Ho Kim, Heather A. Enright, Bruce A. Buchholz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10288 (2024)
The frequency, duration, and size of wildfires have been increasing, and the inhalation of wildfire smoke particles poses a significant risk to human health. Epidemiological studies have shown that wildfire smoke exposure is positively associated wit
Externí odkaz:
https://doaj.org/article/2f952f24a56e4d25adec97b0b3e4ef6d
Autor:
Ho Young Lee, Dorothy J. You, Alexia Taylor-Just, Logan J. Tisch, Ryan D. Bartone, Hannah M. Atkins, Lauren M. Ralph, Silvio Antoniak, James C. Bonner
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) has been reported to exert strong pro-inflammatory and pro-fibrotic adjuvant effects in mouse models of allergic lung disease. However, the molecular mechanisms through
Externí odkaz:
https://doaj.org/article/32e1e4ddbe73477b8a60b356f6b92171
Autor:
Alexia J. Taylor-Just, Mark D. Ihrie, Katherine S. Duke, Ho Young Lee, Dorothy J. You, Salik Hussain, Vamsi K. Kodali, Christina Ziemann, Otto Creutzenberg, Adriana Vulpoi, Flaviu Turcu, Monica Potara, Milica Todea, Sybille van den Brule, Dominique Lison, James C. Bonner
Publikováno v:
Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Inhalation of multi-walled carbon nanotubes (MWCNTs) poses a potential risk to human health. In order to safeguard workers and consumers, the toxic properties of MWCNTs need to be identified. Functionalization has been shown to ei
Externí odkaz:
https://doaj.org/article/f5fdca8869504a2db332be4a4099eecb
Autor:
Dorothy J. You, James C. Bonner
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7310 (2020)
Engineered nanomaterials (ENMs) are products of the emerging nanotechnology industry and many different types of ENMs have been shown to cause chronic inflammation in the lungs of rodents after inhalation exposure, suggesting a risk to human health.
Externí odkaz:
https://doaj.org/article/6eff2307223f432f9d17d530386d35bf
Autor:
Ho Young, Lee, Dorothy J, You, Alexia J, Taylor-Just, Keith E, Linder, Hannah M, Atkins, Lauren M, Ralph, Gabriela, De la Cruz, James C, Bonner
Publikováno v:
Inhal Toxicol
BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) have been associated with respiratory diseases in humans, yet the mechanisms through which PFAS cause susceptibility to inhaled agents is unknown. Herein we investigated the effects of ammonium p
Autor:
Dominique Lison, James C. Bonner, Mark D. Ihrie, M. Todea, Dorothy J. You, Alexia J. Taylor-Just, Monica Potara, Flaviu Turcu, Sybille van den Brule, Christina Ziemann, Salik Hussain, Ho Young Lee, Katherine S. Duke, Vamsi Kodali, Otto Creutzenberg, Adriana Vulpoi
Publikováno v:
Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-18 (2020)
Particle and Fibre Toxicology
Particle and fibre toxicology, Vol. 17, no. 1, p. 60 [1-18] (2020)
Particle and Fibre Toxicology
Particle and fibre toxicology, Vol. 17, no. 1, p. 60 [1-18] (2020)
Background Inhalation of multi-walled carbon nanotubes (MWCNTs) poses a potential risk to human health. In order to safeguard workers and consumers, the toxic properties of MWCNTs need to be identified. Functionalization has been shown to either decr
Publikováno v:
Nanotoxicology
Nickel nanoparticles (NiNPs) are increasingly used in nanotechnology applications, yet information on sex differences in NiNP-induced lung disease is lacking. The goal of this study was to explore mechanisms of susceptibility between male and female
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 83
We previously reported that delivery of nickel nanoparticles (NiNPs) and bacterial lipopolysaccharide (LPS) into the lungs of mice synergistically increased IL-6 production and inflammation, and male mice were more susceptible than female mice. The p
Autor:
Michael J Yaeger, Espen E. Spangenburg, Kymberly M Gowdy, Anandita Pal, Brita Kilburg-Basnyat, Katelyn Dunigan-Russell, Michael Armstrong, S Raza Shaikh, Nichole Reisdorph, Johanna L. Hannan, Miles X Hodge, Sky W Reece, Robert M. Tighe, Dorothy J. You, Jonathan Manke, Debra A Tokarz, Bin Luo, James C. Bonner
Publikováno v:
Toxicol Sci
Ozone (O3) is a criteria air pollutant known to increase the morbidity and mortality of cardiopulmonary diseases. This occurs through a pulmonary inflammatory response characterized by increased recruitment of immune cells into the airspace, pro-infl
Autor:
Kelly A. Shipkowski, James C. Bonner, Ho Young Lee, Dorothy J. You, Alexia J. Taylor-Just, Katherine S. Duke, Mark D. Ihrie
Publikováno v:
NanoImpact
There is increasing evidence that inhaled multi-walled carbon nanotubes (MWCNTs) can have harmful effects on the respiratory system. Rodent studies suggest that individuals with asthma may be susceptible to the adverse pulmonary effects of MWCNTs. As