Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dorothy J Yamamoto"'
Autor:
Michael F Regner, Naomi Saenz, Keeran Maharajh, Dorothy J Yamamoto, Brianne Mohl, Korey Wylie, Jason Tregellas, Jody Tanabe
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164818 (2016)
We hypothesized that compared to healthy controls, long-term abstinent substance dependent individuals (SDI) will differ in their effective connectivity between large-scale brain networks and demonstrate increased directional information from executi
Externí odkaz:
https://doaj.org/article/dc3ab69bf4074b35a926fe49e4b5e8e8
Autor:
Dorothy J Yamamoto, Nancy R Zahniser
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37673 (2012)
Sprague-Dawley rats can be classified as low or high cocaine responders (LCRs or HCRs, respectively) based on their locomotor activity induced by an acute low dose of cocaine. Upon repeated cocaine exposure, LCRs display greater locomotor sensitizati
Externí odkaz:
https://doaj.org/article/59cc6def8ac442bcb6329e8398d7245f
Autor:
Dorothy J. Yamamoto, Jody Tanabe, Mark S. Brown, Ellen L. Burnham, Brianne Sutton, Deborah H. Glueck, Paula L. Hoffman, Boris Tabakoff
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND Acute alcohol produces effects on cerebral metabolism and blood flow. Alcohol is converted to acetate, which serves as a source of energy for the brain and is an agonist at G protein-coupled receptors distributed in different cell types in
Autor:
Jody Tanabe, Kimberly E. Lind, Dorothy J. Yamamoto, Michael F. Regner, Eric J. Gutierrez, Sherry A. McKee
Publikováno v:
Drug and alcohol dependence. 176
Publikováno v:
Drug and alcohol dependence. 180
Behavioral approach, defined as behavior directed toward a reward or novel stimulus, when elevated, may increase one's vulnerability to substance use disorder. Behavioral approach has been associated with relatively greater left compared to right fro
Autor:
Toni L. Richards, Bruce H. Mandt, Richard M. Allen, Diana L. Simmons, Christopher M.C. Ng, Nancy R. Zahniser, Dorothy J. Yamamoto
Publikováno v:
Neuropharmacology. 75:347-355
Behavioral responsiveness to initial cocaine use varies among individuals and may contribute to differential vulnerability to cocaine addiction. Rats also exhibit individual differences in cocaine’s effects and can be classified as low or high coca
Autor:
Bruce H. Mandt, Toni L. Richards, Gaynor A. Larson, Jacki M. Rorabaugh, Christopher M.C. Ng, Nancy R. Zahniser, Dorothy J. Yamamoto, Kelsey Barcomb, Richard M. Allen, Anna M. Nelson
Publikováno v:
Neuroscience & Biobehavioral Reviews. 37:1738-1753
Individual differences are a hallmark of drug addiction. Here, we describe a rat model based on differential initial responsiveness to low dose cocaine. Despite similar brain cocaine levels, individual outbred Sprague-Dawley rats exhibit markedly dif
Autor:
Eric J. Gutierrez, Kimberly E. Lind, Sherry A. McKee, Jody Tanabe, Dorothy J. Yamamoto, Michael F. Regner
Publikováno v:
Drug and alcohol dependence. 173
Background Sex differences in brain structure and clinical course of substance use disorders underscores the need to include women in structural brain imaging studies. The NIH has supported the need for research to address sex differences. We evaluat
Publikováno v:
Pharmacology Biochemistry and Behavior. 88:82-88
Although escalation of consumption is an important characteristic of cocaine dependence, the neurobiological mechanisms that mediate this phenomenon have not been fully described. In this study, we used male, Sprague-Dawley rats to measure the effect
Autor:
Dorothy J. Yamamoto, Joseph T. Sakai, Michael F. Regner, Robert I. Perry, Jody Tanabe, Manish S. Dalwani, Justin M. Honce
Publikováno v:
Radiology. 277(3)
To investigate whether sex modulates the effects of stimulant dependence on gray matter volume (GMV) in patients who have achieved long-term abstinence and to characterize how sex modulates GMV according to specific behavioral measures, such as depen