Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dorothy Hutter"'
Publikováno v:
Mol Cell Biochem
Previous work has shown that expression of the extracellular signal regulated kinase (ERK) is decreased by high density in normal fibroblast cells (BJ), and this was correlated with increased expression of mitogen-activated protein kinase phosphatase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a794755c4fb373e192d28510a3b189c6
https://pubmed.ncbi.nlm.nih.gov/30689107
https://pubmed.ncbi.nlm.nih.gov/30689107
Publikováno v:
Molecular and Cellular Biochemistry. 359:105-113
The molecular signaling events leading to protection from oxidative stress-induced apoptosis upon contact inhibition have not been fully investigated. Previous research has indicated a role for mitogen-activated protein kinases (MAPKs) in the regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4bd831fcd4653cba8d0d09579de9f7c
https://doi.org/10.1007/s11010-011-1004-1
https://doi.org/10.1007/s11010-011-1004-1
Publikováno v:
Protein Expression and Purification. 24:481-488
Expression of enzymatically active mammalian proteins in Escherichia coli can proven to be a challenging task due to poor solubility, improper folding, and lack of adequate posttranslational modification. Expression of mammalian proteins using baculo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52227b6fbd27570fcf56dc4b3e5dccca
https://doi.org/10.1006/prep.2001.1599
https://doi.org/10.1006/prep.2001.1599
Publikováno v:
Molecular and Cellular Biochemistry. 233:107-117
Both the mitogen-activated protein kinase (MAPK) phosphatases MKP-1 and MKP-2 exert important feedback control of MAPK-mediated signaling events. The function of MKP-1 and MKP-2 is regulated via complex mechanisms, ranging from increased transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb2824a8d86d47c27891a928c6a965f0
https://doi.org/10.1023/a:1015502226940
https://doi.org/10.1023/a:1015502226940
Publikováno v:
Molecular and Cellular Biology. 21:8213-8224
Mitogen-activated protein (MAP) kinase phosphatase 1 (MKP-1) has been shown to play a critical role in mediating the feedback control of MAP kinase cascades in a variety of cellular processes, including proliferation and stress responsiveness. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7114c0637067c33c87dc783754d61926
https://doi.org/10.1128/mcb.21.23.8213-8224.2001
https://doi.org/10.1128/mcb.21.23.8213-8224.2001
Publikováno v:
Journal of Biological Chemistry. 276:29440-29449
MKP-2 is a member of the mitogen-activated protein (MAP) kinase phosphatase family which has been suggested to play an important role in the feedback control of MAP kinase-mediated gene expression. Although MKP-2 preferentially inactivates extracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54dfe9a23560f51809423592573d964
https://doi.org/10.1074/jbc.m103463200
https://doi.org/10.1074/jbc.m103463200
Autor:
Ying Huang, Nikki J. Holbrook, Andrew K Chan, Dorothy Hutter, M.Saeed Sheikh, Xiantao Wang, Yusen Liu
Publikováno v:
Journal of Biological Chemistry. 275:18234-18242
Transforming growth factor (TGF)-beta1, a pleiotropic cytokine involved in regulating growth and differentiation, can exert both pro-apoptotic and anti-apoptotic effects depending on the cell type or circumstances. We observed that TGF-beta1 blocked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f9a5daec60553c5cc98ead5e03c897
https://doi.org/10.1074/jbc.m909431199
https://doi.org/10.1074/jbc.m909431199
Autor:
George S. Roth, Yusen Liu, Yoshikage Yo, Wei Chen, Dorothy Hutter, Pinghu Liu, Nikki J. Holbrook
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 55:B125-B134
Numerous studies have demonstrated that the proliferative capacity of cells declines with age. Using rat primary hepatocytes as a model system, we recently demonstrated that this age-related decline in the proliferative response to mitogenic stimulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adce5890a971f39003f89892d5e71cff
https://doi.org/10.1093/gerona/55.3.b125
https://doi.org/10.1093/gerona/55.3.b125
Publikováno v:
Molecular and cellular biochemistry. 308(1-2)
The molecular events, which govern growth control upon contact inhibition have not yet been clearly defined. Previous work has indicated that there is an increase in the expression of mitogen-activated protein kinase phosphatases (MKPs) upon the atta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12ecaae613ac96d1314c0e990d56677
https://pubmed.ncbi.nlm.nih.gov/17906919
https://pubmed.ncbi.nlm.nih.gov/17906919
Publikováno v:
Molecular and cellular biochemistry. 286(1-2)
Despite the understanding of the importance of mitogen-activated protein (MAP) kinase activation in the stimulation of growth, little is known about the role of MAP kinase regulation during contact inhibited growth control. To investigate the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4fde575c60cc6ad74e17c91d4b36ea5
https://pubmed.ncbi.nlm.nih.gov/16467968
https://pubmed.ncbi.nlm.nih.gov/16467968