Study protocol: infectious diseases consortium (I3D) for study on integrated and innovative approaches for management of respiratory infections: respiratory infections research and outcome study (RESPIRO)

Autor: Dorothy Hui Lin Ng, Travis Ren Teen Chia, Barnaby Edward Young, Sapna Sadarangani, Ser Hon Puah, Jenny Guek Hong Low, Gabriel Zherong Yan, Yin Mo, Nicholas Jinghao Ngiam, Samuel Sherng Young Wang, Yan Tong Loo, Faith Evangeline Jie Qi Ong, Andrew Yunkai Li, Sharlene Ho, Lisa Ng, Paul Anantharajah Tambyah, Tsin Wen Yeo

Publikováno v: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-6 (2024)

Abstract Background Community-acquired respiratory infections are a leading cause of illness and death globally. The aetiologies of community-acquired pneumonia remain poorly defined. The RESPIRO study is an ongoing prospective observational cohort s

Externí odkaz: https://doaj.org/article/f90e5cf09a2b4fd8b0d39abfd5369889

Disruption of IL-21 signaling affects T cell-B cell interactions and abrogates protective humoral immunity to malaria.

Autor: Damián Pérez-Mazliah, Dorothy Hui Lin Ng, Ana Paula Freitas do Rosário, Sarah McLaughlin, Béatris Mastelic-Gavillet, Jan Sodenkamp, Garikai Kushinga, Jean Langhorne

Publikováno v: PLoS Pathogens, Vol 11, Iss 3, p e1004715 (2015)

Interleukin-21 signaling is important for germinal center B-cell responses, isotype switching and generation of memory B cells. However, a role for IL-21 in antibody-mediated protection against pathogens has not been demonstrated. Here we show that I

Externí odkaz: https://doaj.org/article/cd124cd36cb24decaa5a49dfa6b3028b

Quantifying the economic cost of antibiotic resistance and the impact of related interventions: rapid methodological review, conceptual framework and recommendations for future studies

Autor: Frank Sandmann, Julie V. Robotham, Mark Jit, Katherine E. Atkins, Koen B. Pouwels, Nantasit Luangasanatip, Dorothy Hui Lin Ng

Publikováno v: BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
BMC Medicine
Jit, M, Ng, D H L, Luangasanatip, N, Sandmann, F, Atkins, K E, Robotham, J V & Pouwels, K B 2020, ' Quantifying the economic cost of antibiotic resistance and the impact of related interventions rapid methodological review, conceptual framework and recommendations for future studies ', BMC Medicine, vol. 18, no. 1, pp. 38 . https://doi.org/10.1186/s12916-020-1507-2

Background Antibiotic resistance (ABR) poses a major threat to health and economic wellbeing worldwide. Reducing ABR will require government interventions to incentivise antibiotic development, prudent antibiotic use, infection control and deployment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d6cfdd96c3bc731e68301b70b0bf3d
http://link.springer.com/article/10.1186/s12916-020-1507-2

Efficacy of commercial mouth-rinses on SARS-CoV-2 viral load in saliva: Randomized Control Trial in Singapore

Autor: Dorothy Hui Lin Ng, Kheng Sit Lim, Deborah Lai, Kwan Ki Karrie Ko, Bee Tin Goh, Preethi Balan, Moi Lin Ling, Chaminda Jayampath Seneviratne, Nadeeka S. Udawatte, Indumathi Venkatachalam, Lynette Oon, Xiang Ying Jean Sim

Publikováno v: Infection

The presence of high SARS-coronavirus 2 (SARS-CoV-2) titres in saliva may result in transmission of the virus and increase the risk of COVID-19 infection. This is particularly important as significant amounts of aerosols are generated during dental p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853908f4c37b539b2777800b1140ccda
https://doi.org/10.1101/2020.09.14.20186494

Bacillus Calmette–Guérin scar flare after an mRNA SARS-CoV-2 vaccine

Autor: Dorothy Hui Lin Ng, Jenny G. Low, Darren Wan-Teck Lim

Publikováno v: CMAJ : Canadian Medical Association Journal

A 34-year-old woman presented to our outpatient clinic with swelling and erythema over the site of her childhood Bacillus Calmette–Guerin (BCG) vaccination scar, 7 days after receiving her first dose of the BNT162b2 (Pfizer-BioNTech) messenger ribo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1b5e943e83917bc0e2935ec860db9e
https://doi.org/10.1503/cmaj.210696