Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Dorothy Hu"'
Autor:
Zhengtao Lv, Jiaming Zhang, Shuang Liang, Chenhe Zhou, Dorothy Hu, Daniel J. Brooks, Mary L. Bouxsein, Beate Lanske, Paul Kostenuik, Francesca Gori, Roland Baron
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Osteocytes express parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptors and respond to the PTHrP analog abaloparatide (ABL) and to the PTH 1-34 fragment teriparatide (TPTD), which are used to treat osteoporosis. Several studies indicate ov
Externí odkaz:
https://doaj.org/article/1fa370aa0f214e7faf41ab04fe5dc50a
Autor:
Heike Arlt, Tara Mullarkey, Dorothy Hu, Roland Baron, Michael S. Ominsky, Bruce Mitlak, Beate Lanske, Tatiana Besschetnova
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100291- (2020)
Intermittent administration of PTH type 1 receptor (PTH1R) agonists increases bone remodeling, with greater stimulation of bone formation relative to bone resorption causing net gains in bone mass. This pharmacodynamic feature underlies the bone-buil
Externí odkaz:
https://doaj.org/article/f77974bf4fd94ac981d1a13b3f54cd1a
Autor:
Ruiying Chen, Han Dong, Raval, Dhairya, Maridas, David, Baroi, Sudipta, Kun Chen, Dorothy Hu, Berry, Shawn R., Baron, Roland, Greenblatt, Matthew B., Gori, Francesca
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 11/14/2023, Vol. 120 Issue 46, p1-12, 26p
Autor:
Rebecca V. Mountain, Audrie L. Langlais, Dorothy Hu, Roland Baron, Christine W. Lary, Katherine J. Motyl
Publikováno v:
bioRxiv
Social isolation is a potent form of psychosocial stress and is a growing public health concern, particularly among older adults. Even prior to the onset of the COVID-19 pandemic, which has significantly increased the prevalence of isolation and lone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3150849cd1944ed705c7a61e581b84a
https://doi.org/10.1101/2023.01.27.525939
https://doi.org/10.1101/2023.01.27.525939
Autor:
Rebecca V. Mountain, Audrie L. Langlais, Dorothy Hu, Roland Baron, Christine W. Lary, Katherine J. Motyl
Publikováno v:
Bone. 172:116762
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::902e3311d03f53d878e08866378d0874
https://doi.org/10.1016/j.bone.2023.116762
https://doi.org/10.1016/j.bone.2023.116762
Publikováno v:
Proceedings of the National Academy of Sciences. 116:14138-14143
Loss-of-function mutations in the Wnt inhibitor secreted frizzled receptor protein 4 (SFRP4) cause Pyle’s disease (OMIM 265900), a rare skeletal disorder characterized by wide metaphyses, significant thinning of cortical bone, and fragility fractur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3ab81610daf64de1c348fea6caae63
https://doi.org/10.1073/pnas.1900881116
https://doi.org/10.1073/pnas.1900881116
Publikováno v:
Bone. 120:487-494
The uniaxial tibial loading model is commonly used to promote bone formation through mechanoadaptation in mice. Sciatic neurectomy on the other hand recruits osteoclasts, which results in bone loss. Previous studies have shown that combining sciatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc3c6adc4becc8eb69a142f1fb2dde8
https://doi.org/10.1016/j.bone.2018.12.017
https://doi.org/10.1016/j.bone.2018.12.017
Autor:
Mary L. Bouxsein, Georgios Koukos, Mary Mohrin, Lama Alabdulaaly, Sakshi Bhargava, Justin Liu, Adam Freund, Kayley Hake, Roland Baron, Daniel J. Brooks, Jose Zavala-Solorio, John Maxwell Trumble, Jonathan S. Paw, Yuliya Kutskova, Dorothy Hu, Ganesh Kolumam, Alyssa Brito
Publikováno v:
Aging Cell
Pregnancy‐associated plasma protein‐A (PAPP‐A) is a secreted metalloprotease that increases insulin‐like growth factor (IGF) availability by cleaving IGF‐binding proteins. Reduced IGF signaling extends longevity in multiple species, and con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299f2a7691c9640b3391943935160d60
http://europepmc.org/articles/PMC7963332
http://europepmc.org/articles/PMC7963332
Autor:
Tatiana Besschetnova, Tara Mullarkey, Bruce H. Mitlak, Beate Lanske, Heike Arlt, Michael S. Ominsky, Roland Baron, Dorothy Hu
Publikováno v:
Bone Reports, Vol 13, Iss, Pp 100291-(2020)
Bone Reports
Bone Reports
Intermittent administration of PTH type 1 receptor (PTH1R) agonists increases bone remodeling, with greater stimulation of bone formation relative to bone resorption causing net gains in bone mass. This pharmacodynamic feature underlies the bone-buil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ff71b72a043c94c5ab00a04624040e
http://www.sciencedirect.com/science/article/pii/S2352187220300516
http://www.sciencedirect.com/science/article/pii/S2352187220300516
Autor:
Dorothy Hui Lin Ng, Travis Ren Teen Chia, Barnaby Edward Young, Sapna Sadarangani, Ser Hon Puah, Jenny Guek Hong Low, Gabriel Zherong Yan, Yin Mo, Nicholas Jinghao Ngiam, Samuel Sherng Young Wang, Yan Tong Loo, Faith Evangeline Jie Qi Ong, Andrew Yunkai Li, Sharlene Ho, Lisa Ng, Paul Anantharajah Tambyah, Tsin Wen Yeo
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Background Community-acquired respiratory infections are a leading cause of illness and death globally. The aetiologies of community-acquired pneumonia remain poorly defined. The RESPIRO study is an ongoing prospective observational cohort s
Externí odkaz:
https://doaj.org/article/f90e5cf09a2b4fd8b0d39abfd5369889