Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Dorothy E. Oorschot"'
Autor:
David K. Bilkey, Stephanie M. Hughes, Rachel J. Sizemore, Roseanna A Smither, Hollie E Wicky, Steve Seo, Louise C. Parr-Brownlie, Dorothy E. Oorschot, Karen L Reader
Publikováno v:
Journal of Comparative Neurology. 529:3946-3973
To develop new therapies for schizophrenia, evidence accumulated over decades highlights the essential need to investigate the GABAergic synapses that presynaptically influence midbrain dopaminergic neurons. Since current technology restricts these s
Publikováno v:
Neuroinformatics. 20(4)
Neuronal networks are regulated by three-dimensional spatial and structural properties. Despite robust evidence of functional implications in the modulation of cognition, little is known about the three-dimensional internal organization of cholinergi
Autor:
Dorothy E Oorschot
Publikováno v:
Image Analysis and Stereology, Vol 30, Iss 1, Pp 1-9 (2011)
The use of indirect measures of neuronal injury or neuroprotection, such as brain weight or the neuronal density of neurons, can lead to misinterpretations of biological processes. The use of modern stereological methods to directly measure the absol
Externí odkaz:
https://doaj.org/article/5fbd1808361c48afa37545f1bd7ed247
Autor:
Haylee K. Basham, Benjamin E. Aghoghovwia, Dorothy E. Oorschot, Panagiotis Papaioannou, Steve Seo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7862, p 7862 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences
Volume 22
Issue 15
Perinatal hypoxia-ischemia (HI) is a major cause of striatal injury. Delayed post-treatment with adult-sourced bone marrow-derived mesenchymal stem cells (BMSCs) increased the absolute number of striatal medium-spiny neurons (MSNs) following perinata
Publikováno v:
The Anatomical Record. 302:2040-2048
Measurement of long-term functional and anatomical outcomes in the same animal is considered a powerful strategy for correlating structure with function. In a neonatal animal model of hypoxic-ischemic brain injury that is relevant to cerebral palsy,
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1487 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1487 (2020)
Perinatal hypoxic-ischemic encephalopathy (HIE) remains a major cause of morbidity and mortality. Moderate hypothermia (33.5 °C) is currently the sole established standard treatment. However, there are a large number of infants for whom this therapy
Autor:
Nicola J Batchelor, Savana R Woodcock, Rachel L Sanders, Rebecca L. Kelley, Dorothy E. Oorschot, Michael W. Pankhurst
Publikováno v:
The Journal of endocrinology. 237(2)
Anti-Müllerian hormone (AMH) is an ovarian regulator that affects folliculogenesis. AMH inhibits the developmental activation of the dormant primordial follicles and the oocyte within. In more mature follicles, AMH reduces granulosa cell sensitivity
Autor:
John N. J. Reynolds, Naili Lin, Louise C. Parr-Brownlie, Liping Goddard, Timothy Wastney, Rachel J. Sizemore, Dorothy E. Oorschot, Rong Zhang
Publikováno v:
Journal of Comparative Neurology. 524:1062-1080
Elucidating the link between cellular activity and goal-directed behavior requires a fuller understanding of the mechanisms underlying burst firing in midbrain dopaminergic neurons and those that suppress activity during aversive or non-rewarding eve
Autor:
Dorothy E. Oorschot, Ashraf R. Amer
Publikováno v:
Pediatric neurology. 84
Perinatal hypoxia-ischemia is a major cause of neonatal morbidity. It generates primary neuronal damage of the neonatal brain and later secondary damage when reperfusion of the ischemic brain tissue causes a surge of oxygen free radicals and inflamma
Autor:
Kuei Y. Tseng, Jason P. Gray, John N. J. Reynolds, Jonathan Shemmell, Kajsa M. Igelström, Melissa D. Barry, Laura J. Boddington, Dorothy E. Oorschot
Publikováno v:
Experimental Neurology. 261:258-266
Following a cerebral cortex injury such as stroke, excessive inhibition around the core of the injury is thought to reduce the potential for new motor learning. In part, this may be caused by an imbalance of interhemispheric inhibition (IHI); therefo