Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Dorothy E Shippen"'
Publikováno v:
eLife, Vol 9 (2020)
HOAP is a telomere-binding protein that has a conserved role in Drosophila, but it also needs to evolve quickly to restrict telomeric retrotransposons.
Externí odkaz:
https://doaj.org/article/5592dac9ea0944e9a9cf3d926e28a851
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005281 (2015)
Long noncoding RNAs (lncRNAs) have emerged as critical factors in many biological processes, but little is known about how their regulatory functions evolved. One of the best-studied lncRNAs is TER, the essential RNA template for telomerase reverse t
Externí odkaz:
https://doaj.org/article/64ca74a1f97c4f0f9272d09f5c13f9a8
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004738 (2014)
Protection of Telomeres 1 (POT1) is a conserved nucleic acid binding protein implicated in both telomere replication and chromosome end protection. We previously showed that Arabidopsis thaliana POT1a associates with the TER1 telomerase RNP, and is r
Externí odkaz:
https://doaj.org/article/2243e6b11ed545e593a41e61cb422721
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88872 (2014)
Maintaining the length of the telomere tract at chromosome ends is a complex process vital to normal cell division. Telomere length is controlled through the action of telomerase as well as a cadre of telomere-associated proteins that facilitate repl
Externí odkaz:
https://doaj.org/article/d215f99002d14e2f96741c8ad8aaa0f9
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
The telomerase reverse transcriptase promotes genome integrity by continually synthesizing a short telomere repeat sequence on chromosome ends. Telomerase is a ribonucleoprotein complex whose integral RNA subunit TER contains a template domain with a
Externí odkaz:
https://doaj.org/article/a1acb25863b3485c8ed141dd184435cc
Autor:
Eugene V Shakirov, Dorothy E Shippen
Publikováno v:
Frontiers in Plant Science, Vol 3 (2012)
Telomeres, the essential terminal regions of linear eukaryotic chromosomes, consist of G-rich DNA repeats bound by a plethora of associated proteins. While the general pathways of telomere maintenance are evolutionarily conserved, individual telomere
Externí odkaz:
https://doaj.org/article/05d90bc38f3a480ea8b7f2a67cebc71f
Autor:
Borja Barbero Barcenilla, Alexander D. Meyers, Claudia Castillo-González, Pierce Young, Ji-Hee Min, Jiarui Song, Chinmay Phadke, Eric Land, Emma Canaday, Imara Y. Perera, Susan M. Bailey, Roberto Aquilano, Sarah E. Wyatt, Dorothy E. Shippen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Spaceflight-induced changes in astronaut telomeres have garnered significant attention in recent years. While plants represent an essential component of future long-duration space travel, the impacts of spaceflight on plant telomeres and tel
Externí odkaz:
https://doaj.org/article/cf394e32ac1549f78be3a3a42b35b69c
Autor:
Borja Barbero Barcenilla, Ishan Kundel, Emily Hall, Nicolas Hilty, Pavel Ulianich, Jillian Cook, Jake Turley, Monisha Yerram, Ji-Hee Min, Claudia Castillo-González, Dorothy E. Shippen
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
NASA envisions a future where humans establish a thriving colony on the Moon by 2050. Plants will be essential for this endeavor, but little is known about their adaptation to extraterrestrial bodies. The capacity to grow plants in lunar regolith wou
Externí odkaz:
https://doaj.org/article/26c12f77058d4c99abec2be8db2bd12b
Autor:
Liliia R. Abdulkina, Callie Kobayashi, John T. Lovell, Inna B. Chastukhina, Behailu B. Aklilu, Inna A. Agabekian, Ana V. Suescún, Lia R. Valeeva, Chuluuntsetseg Nyamsuren, Galina V. Aglyamova, Margarita R. Sharipova, Dorothy E. Shippen, Thomas E. Juenger, Eugene V. Shakirov
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Major effect loci controlling natural, heritable variation in telomere length are not known. Here, the authors use QTL mapping and transgenic manipulations in Arabidopsis to implicate the rRNA-processing genes NOP2A and RPL5 in telomere length set po
Externí odkaz:
https://doaj.org/article/53781ea65a47466f9ff11e14b4d15555
Publikováno v:
Nucleic Acids Research
The recent discovery of the bona-fide telomerase RNA (TR) from plants reveals conserved and unique secondary structure elements and the opportunity for new insight into the telomerase RNP. Here we examine how two highly conserved proteins previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52d6624dc3bc33299b7d570e21aff18
https://doi.org/10.1093/nar/gkab699
https://doi.org/10.1093/nar/gkab699