Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Dorothy E, Lewis"'
Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells
Autor:
Jacob Couturier, Aaron F. Orozco, Hongbing Liu, Sona Budhiraja, Edward B. Siwak, Pramod N. Nehete, K. Jagannadha Sastry, Andrew P. Rice, Dorothy E. Lewis
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background The regulatory cyclin, Cyclin T1 (CycT1), is a host factor essential for HIV-1 replication in CD4 T cells and macrophages. The importance of CycT1 and the Positive Transcription Elongation Factor b (P-TEFb) complex for HIV replica
Externí odkaz:
https://doaj.org/article/bbbc427c37f54fd1876bca78a6800267
Autor:
Jacob Couturier, Alli M. Nuotio-Antar, Neeti Agarwal, Gregory K. Wilkerson, Pradip Saha, Viraj Kulkarni, Samir K. Lakhashe, Juan Esquivel, Pramod N. Nehete, Ruth M. Ruprecht, K. Jagannadha Sastry, Jennifer M. Meyer, Lori R. Hill, Jordan E. Lake, Ashok Balasubramanyam, Dorothy E. Lewis
Publikováno v:
Adipocyte, Vol 8, Iss 1, Pp 154-163 (2019)
CD36 is a multifunctional scavenger receptor and lipid transporter implicated in metabolic and inflammatory pathologies, as well as cancer progression. CD36 is known to be expressed by adipocytes and monocytes/macrophages, but its expression by T cel
Externí odkaz:
https://doaj.org/article/79724c716a6545339a21c7591ee06bf5
Autor:
Neeti Agarwal, Dinakar Iyer, Chiara Gabbi, Pradip Saha, Sanjeet G. Patel, Qianxing Mo, Benny Chang, Biman Goswami, Ulrich Schubert, Jeffrey B. Kopp, Dorothy E. Lewis, Ashok Balasubramanyam
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract HIV patients develop hepatic steatosis. We investigated hepatic steatosis in transgenic mice expressing the HIV-1 accessory protein Vpr (Vpr-Tg) in liver and adipose tissues, and WT mice infused with synthetic Vpr. Vpr-Tg mice developed incr
Externí odkaz:
https://doaj.org/article/c8f0f384a6314c60a5bd96567b68a7fd
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/feb0635bca25471cadfcaa73836a5ae8
Autor:
Fernanda P. Pons-Faudoa, Nicola Di Trani, Antons Sizovs, Kathryn A. Shelton, Zoha Momin, Lane R. Bushman, Jiaqiong Xu, Dorothy E. Lewis, Sandra Demaria, Trevor Hawkins, James F. Rooney, Mark A. Marzinke, Jason T. Kimata, Peter L. Anderson, Pramod N. Nehete, Roberto C. Arduino, K. Jagannadha Sastry, Alessandro Grattoni
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 981 (2020)
HIV-1 is a chronic disease managed by strictly adhering to daily antiretroviral therapy (ART). However, not all people living with HIV-1 have access to ART, and those with access may not adhere to treatment regimens increasing viral load and disease
Externí odkaz:
https://doaj.org/article/bc54b683a78a4c54871a1a7b1e376c61
Autor:
Brian Skaug, Xinjian Guo, Yuanteng Jeff Li, Julio Charles, Kay T Pham, Jacob Couturier, Dorothy E Lewis, Claudia Bracaglia, Ivan Caiello, Maureen D Mayes, Shervin Assassi
Publikováno v:
Rheumatology.
ObjectivesPolymorphism in a coding region of deoxyribonuclease I-like III (DNASE1L3), causing amino acid substitution of Arg-206 to Cys (R206C), is a robustly replicated heritable risk factor for SSc and other autoimmune diseases. DNASE1L3 is secrete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386c107518a8c639e2de0d2fa83209c6
https://doi.org/10.1093/rheumatology/kead050
https://doi.org/10.1093/rheumatology/kead050
Publikováno v:
Clinical Immunology ISBN: 9780702081651
The human immune system has sites of production, i.e., bone marrow and the thymus; and sites of differentiation and proliferation, i.e., lymph nodes and the spleen. Immune organization also occurs in the lung, gastrointestinal tract, skin, and adipos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbb78d8f483353ec4b57775105a0340
https://doi.org/10.1016/b978-0-7020-8165-1.00002-2
https://doi.org/10.1016/b978-0-7020-8165-1.00002-2
Autor:
Lane R. Bushman, K. Jagannadha Sastry, Trevor Hawkins, Antons Sizovs, Alessandro Grattoni, Kathryn A. Shelton, Mark A. Marzinke, Sandra Demaria, Roberto C. Arduino, Pramod N. Nehete, Peter L. Anderson, Fernanda P. Pons-Faudoa, Dorothy E. Lewis, James F. Rooney, Jiaqiong Xu, Zoha Momin, Jason T. Kimata, Nicola Di Trani
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 12, Iss 981, p 981 (2020)
Volume 12
Issue 10
Pharmaceutics, Vol 12, Iss 981, p 981 (2020)
Volume 12
Issue 10
HIV-1 is a chronic disease managed by strictly adhering to daily antiretroviral therapy (ART). However, not all people living with HIV-1 have access to ART, and those with access may not adhere to treatment regimens increasing viral load and disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f35279e0bf8a3aaf986170919c86fc6
http://europepmc.org/articles/PMC7590004
http://europepmc.org/articles/PMC7590004
Autor:
Viraj Kulkarni, Jacob Couturier, Ashok Balasubramanyam, Ruth M. Ruprecht, Lori R. Hill, Alli M. Nuotio-Antar, Gregory K. Wilkerson, Neeti Agarwal, Juan Esquivel, K. Jagannadha Sastry, Dorothy E. Lewis, Jennifer M. Meyer, Samir K. Lakhashe, Pradip K. Saha, Pramod N. Nehete, Jordan E. Lake
Publikováno v:
Adipocyte, Vol 8, Iss 1, Pp 154-163 (2019)
Adipocyte
Adipocyte
CD36 is a multifunctional scavenger receptor and lipid transporter implicated in metabolic and inflammatory pathologies, as well as cancer progression. CD36 is known to be expressed by adipocytes and monocytes/macrophages, but its expression by T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff9db25a573acaf05d99c81499cd337
https://doaj.org/article/79724c716a6545339a21c7591ee06bf5
https://doaj.org/article/79724c716a6545339a21c7591ee06bf5
Publikováno v:
Virology. 522:193-198
The related NEAT1_1 and NEAT1_2 long noncoding RNAs (lnc RNAs) have been recently implicated in innate immunity against viral infection. We used CRISPR-Cas9 to generate Jurkat CD4(+) T cell lines with a knockout (KO) of the NEAT1 gene. Viabilities of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd4dee0a0cdd5b2983cef790e525d20
https://doi.org/10.1016/j.virol.2018.07.020
https://doi.org/10.1016/j.virol.2018.07.020