Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Dorothy C. Bennett"'
Autor:
Jiyoung Lee, Yeonjoo Kim, Paris Ataliotis, Hyung-Goo Kim, Dae-Won Kim, Dorothy C. Bennett, Nigel A. Brown, Lawrence C. Layman, Soo-Hyun Kim
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract WDR11, a gene associated with Kallmann syndrome, is important in reproductive system development but molecular understanding of its action remains incomplete. We previously reported that Wdr11-deficient embryos exhibit defective ciliogenesis
Externí odkaz:
https://doaj.org/article/fb98f512d0be43009776e9557a2f4d61
Publikováno v:
Biology Open, Vol 12, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/0b2627e3800c40e7b551bcd7267d83cb
Autor:
Philip S. Goff, Joanna T. Castle, Jaskaren S. Kohli, Elena V. Sviderskaya, Dorothy C. Bennett
Publikováno v:
Current Protocols. 3
Autor:
Claire J Cairney, Lauren S Godwin, Alan E Bilsland, Sharon Burns, Katrina H Stevenson, Lynn McGarry, John Revie, Jon D Moore, Ceri M Wiggins, Rebecca S Collinson, Clare Mudd, Elpida Tsonou, Mahito Sadaie, Dorothy C Bennett, Masashi Narita, Christopher J Torrance, W Nicol Keith
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006942 (2017)
Senescence is a universal barrier to immortalisation and tumorigenesis. As such, interest in the use of senescence-induction in a therapeutic context has been gaining momentum in the past few years; however, senescence and immortalisation remain unde
Externí odkaz:
https://doaj.org/article/9c37fdc4728e4b2584673b3d2d9b5b8b
Autor:
Linh Le, Elena V. Sviderskaya, Ariel J Lefkovith, Emily Latteri, Elena Oancea, Michael S. Marks, Kirk D. Haltaufderhyde, Megan K Dennis, Iliana E. Escobar, Tina Ho, Dorothy C. Bennett, Lynn Plowright
Publikováno v:
Molecular Biology of the Cell
SLC45A2 encodes a putative transporter expressed primarily in pigment cells. SLC45A2 mutations cause oculocutaneous albinism type 4 (OCA4) and polymorphisms are associated with pigmentation variation, but the localization, function, and regulation of
Autor:
Dorothy C. Bennett, Atticus H. Hainsworth, Emma Jane Norton, Lawrence C. Kenyon, Leslie R. Bridges, Margaret M. Esiri
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 78:1066-1072
Cerebral small vessel disease (cSVD) in penetrating arteries is a major cause of age-related morbidity. Cellular senescence is a molecular process targeted by novel senolytic drugs. We quantified senescence in penetrating arteries and tested whether
Autor:
Andrew J Muinonen-Martin, Olivia Susanto, Qifeng Zhang, Elizabeth Smethurst, William J Faller, Douwe M Veltman, Gabriela Kalna, Colin Lindsay, Dorothy C Bennett, Owen J Sansom, Robert Herd, Robert Jones, Laura M Machesky, Michael J O Wakelam, David A Knecht, Robert H Insall
Publikováno v:
PLoS Biology, Vol 12, Iss 10, p e1001966 (2014)
The high mortality of melanoma is caused by rapid spread of cancer cells, which occurs unusually early in tumour evolution. Unlike most solid tumours, thickness rather than cytological markers or differentiation is the best guide to metastatic potent
Externí odkaz:
https://doaj.org/article/d3993f4afdf3405ab98357b4e65f0fe6
Autor:
David J. Owen, Dorothy C. Bennett, Yueyao Zhu, Graça Raposo-Benedetti, Elena V. Sviderskaya, Shanna L. Bowman, Dawn C. Harper, Michael S. Marks, Linh Le, Megan K. Dennis, Alexander C. Theos, Anand Sitaram
Publikováno v:
The Journal of Cell Biology
Bowman et al. show that in melanocytes, the vSNARE VAMP7 is sorted from endosomes into tubular membrane transport carriers bound for maturing melanosomes in a complex with the tSNARE syntaxin 13 via redundant recognition of each SNARE by an AP-3–BL
Autor:
Julia Sirés-Campos, Conchi Olivares, Celia Jiménez-Cervantes, Idoya Martínez-Vicente, José C. García-Borrón, Dorothy C. Bennett, Marta Abrisqueta, María Castejón-Griñán, Cecilia Herraiz
Publikováno v:
Cancers
Volume 12
Issue 10
Cancers, Vol 12, Iss 2840, p 2840 (2020)
Volume 12
Issue 10
Cancers, Vol 12, Iss 2840, p 2840 (2020)
The mouse mahoganoid mutation abrogating Mahogunin Ring Finger-1 (MGRN1) E3 ubiquitin ligase expression causes hyperpigmentation, congenital heart defects and neurodegeneration. To study the pathophysiology of MGRN1 loss, we compared Mgrn1-knockout m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af95fb77ecba31031e6c59ee95f6ba9d
https://openaccess.sgul.ac.uk/id/eprint/112462/1/cancers-12-02840.pdf
https://openaccess.sgul.ac.uk/id/eprint/112462/1/cancers-12-02840.pdf
Autor:
Hyung-Goo Kim, Yeonjoo Kim, Paris Ataliotis, Jiyoung Lee, Soo-Hyun Kim, Dae-Won Kim, Nigel A. Brown, Dorothy C. Bennett, Lawrence C. Layman
Mutations ofWDR11are associated with Kallmann syndrome (KS) and congenital hypogonadotrophic hypogonadism (CHH), typically caused by defective functions of gonadotrophin-releasing hormone (GnRH) neurones in the brain. We previously reported that Wdr1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7f42148384263da98b6c5b444e4ed86
https://doi.org/10.1101/2020.09.06.284927
https://doi.org/10.1101/2020.09.06.284927