Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dorothy Benton"'
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305121 (2024)
Neurofibromatosis type 2 is a genetic disorder that results in the formation and progressive growth of schwannomas, ependymomas, and/or meningiomas. The NF2 gene encodes the Merlin protein, which links cell cortical elements to the actin cytoskeleton
Externí odkaz:
https://doaj.org/article/ea99a41025d443cbbb48ac461e1785c5
Autor:
Dorothy Benton, Eva C Jaeger, Arielle Kilner, Ashley Kimble, Josh Lowry, Emily M Schleicher, Kaiden M Power, Danielle Uibel, Caprice Eisele, Bruce Bowerman, Rebecca Lyczak
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
AbstractPuromycin-sensitive aminopeptidases are found across phyla and are known to regulate the cell-cycle and play a protective role in neurodegenerative disease. PAM-1 is a puromycin-sensitive aminopeptidase important for meiotic exit and polarity
Externí odkaz:
https://doaj.org/article/f0f22e19267d43889d9d99505a384936
Publikováno v:
Biochem Soc Trans
Three elements of the Hippo tumor suppressor pathway — MST1/2, SAV1, and RASSF1–6 — share in common a C-terminal interaction motif termed the SARAH domain. Proteins containing this domain are capable of self-association as homodimers and also o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac17bb27e86c519a4c7efc784a958a6
https://doi.org/10.1042/bst20200559
https://doi.org/10.1042/bst20200559
Autor:
Dorothy Benton, Jonathan Chernoff
Publikováno v:
Cancer Research. 83:2629-2629
Neurofibromatosis 2 (NF2) Syndrome is a rare, but devastating genetic condition that leads to non-cancerous tumors of the nervous system. NF2 patients are likely to develop Schwannomas on the eighth cranial nerve that lead to progressive deafness and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1609a9c0c46806fbfff5f2cece5b00b1
https://doi.org/10.1158/1538-7445.am2023-2629
https://doi.org/10.1158/1538-7445.am2023-2629
Autor:
Josh Lowry, Kaiden M Power, Dorothy Benton, Eva C. Jaeger, Emily M Schleicher, Caprice Eisele, Ashley Kimble, Danielle Uibel, Rebecca Lyczak, Bruce Bowerman, Arielle Kilner
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
Puromycin-sensitive aminopeptidases are found across phyla and are known to regulate the cell-cycle and play a protective role in neurodegenerative disease. PAM-1 is a puromycin-sensitive aminopeptidase important for meiotic exit and polarity establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fba02de313e2f8b98fcd5a749345bdc
https://doi.org/10.1093/g3journal/jkab063
https://doi.org/10.1093/g3journal/jkab063
Autor:
Dorothy Benton, Jonathan Chernoff
Publikováno v:
Cancer Discov
Diffuse gastric cancer (DGC) is a lethal malignancy lacking effective systemic therapy. Among the most provocative recent results in DGC has been that of highly recurrent missense mutations in the GTPase RHOA. The function of these mutations has rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c9c8e3d934c11771cfe5e630c7eefe
https://pubmed.ncbi.nlm.nih.gov/31771969
https://pubmed.ncbi.nlm.nih.gov/31771969