Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Dorothy B. Villee"'
Autor:
John F. Crigler, Dorothy B. Villee
Publikováno v:
Clinics in Perinatology. 3:211-220
Tn this disorder, genetic males under most circumstances show sexual precocity, whereas genetic females exposed to excessive amounts of androgens during early development may be born with ambiguous external genitalia. Aspects discussed include bioche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abd527b1206faccd17725b7fcf49fb50
https://doi.org/10.1016/s0095-5108(18)31281-8
https://doi.org/10.1016/s0095-5108(18)31281-8
Autor:
Dorothy B. Villee, Joseph N. Fisher
Publikováno v:
Advances in Enzyme Regulation. 13:315-328
The effects of ACTH on testicular enzymes was studied using human testicular tumors from patients with a genetic deficiency of 21-hydroxylase and a resulting unsuppressed secretion of ACTH from the pituitary. The human tumor cells from patients off g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fd840f231a0e9b9de8dcbce3dfa12de
https://doi.org/10.1016/0065-2571(75)90022-9
https://doi.org/10.1016/0065-2571(75)90022-9
Publikováno v:
Journal of Urology. 129:660-664
A murine whole organ metanephric culture system was designed to study the developmental aspects of mammalian nephrogenesis. Metanephros and ureteric bud were removed from CFI albino mouse embryos at 13.5 +/- 0.4 days gestation, and grown in Dulbecco'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31227c749f52c860f6b8e2e470479545
https://doi.org/10.1016/s0022-5347(17)52273-9
https://doi.org/10.1016/s0022-5347(17)52273-9
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 26:381-392
Slices of an interstitial cell tumor of the testis removed from a -yr-old boy were incubated with acetate-1-14C. Labeled androst-4-ene-3,17-dione, 11β-hydroxyandrost-4-ene-3,17-dione, androst-4-ene-3,11,17-trione, 3β-hydroxypregn-5-en-20-one, 17-hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3565b51d97062dd9fe9061210b43aab0
https://doi.org/10.1210/jcem-26-4-381
https://doi.org/10.1210/jcem-26-4-381
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 28:983-991
The metabolism of pregnenolone-7α-3H has been studied in vitro in an aldosterone producing tumor and in the adrenal tissue adjacent to the tumor. The predominant products in the incubation of the tumor tissue were progesterone, and lesser amounts of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15bf6ffcdc06abab18f474f3158020b
https://doi.org/10.1210/jcem-28-7-983
https://doi.org/10.1210/jcem-28-7-983
Publikováno v:
Endocrinology. 69:354-372
Slices and homogenates of human fetal adrenals incubated with progesterone-4-C14 were shown to possess the enzymes necessary for converting this to deoxycorticosterone, 17-hydroxyprogesterone, and 16±-hydroxyprogesterone. The amount of product forme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2195d70430f49416a27f2454aab7b21e
https://doi.org/10.1210/endo-69-2-354
https://doi.org/10.1210/endo-69-2-354
Autor:
Dorothy B. Villee, John D. Crawford, Margaret H. MacGillivray, Robert E. Scully, Bernard Kliman
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 25:506-513
Testicular tissue removed from a 15½-yr-old boy with delayed sexual maturation, despite normal levels of urinary gonadotropins for 2 yr, was shown to be capable of converting pregnenolone-7α-3H to androstenedione, testosterone, 17-hydroxyprogestero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af1b1f8d0e46899600780cb5852858b
https://doi.org/10.1210/jcem-25-4-506
https://doi.org/10.1210/jcem-25-4-506
Autor:
Dorothy B. Villee
Publikováno v:
Clinical Pharmacology & Therapeutics. 14:705-713
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eacafa2b34889d311a49aaa48e5bb98
https://doi.org/10.1002/cpt1973144part2705
https://doi.org/10.1002/cpt1973144part2705
Publikováno v:
Pediatrics. 43:207-216
Two boys with classical progeria have been studied by a variety of laboratories in the Boston area. Evidence for unresponsiveness to growth hormone, relative insulin resistance, and highly cross-linked collagen is presented. The data support the conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72bf5dc92a8c7924cee24b3a0a366c06
https://doi.org/10.1542/peds.43.2.207
https://doi.org/10.1542/peds.43.2.207
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 27:1112-1122
A 16-yr-old girl with a virilizing adrenocortical carcinoma was studied clinically before and after surgery, and portions of the tumor were incubated in vitro with a variety of labeled steroids. The virilization of the patient was explained by a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::672a194a6293056772cb9d3027b7a7af
https://doi.org/10.1210/jcem-27-8-1112
https://doi.org/10.1210/jcem-27-8-1112