Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Dorothy B. Villee"'
Autor:
Clement, David H.
Publikováno v:
American Scientist, 1974 Sep 01. 62(5), 605-605.
Externí odkaz:
https://www.jstor.org/stable/27845105
Autor:
John F. Crigler, Dorothy B. Villee
Publikováno v:
Clinics in Perinatology. 3:211-220
Tn this disorder, genetic males under most circumstances show sexual precocity, whereas genetic females exposed to excessive amounts of androgens during early development may be born with ambiguous external genitalia. Aspects discussed include bioche
Autor:
Dorothy B. Villee, Joseph N. Fisher
Publikováno v:
Advances in Enzyme Regulation. 13:315-328
The effects of ACTH on testicular enzymes was studied using human testicular tumors from patients with a genetic deficiency of 21-hydroxylase and a resulting unsuppressed secretion of ACTH from the pituitary. The human tumor cells from patients off g
Publikováno v:
Journal of Urology. 129:660-664
A murine whole organ metanephric culture system was designed to study the developmental aspects of mammalian nephrogenesis. Metanephros and ureteric bud were removed from CFI albino mouse embryos at 13.5 +/- 0.4 days gestation, and grown in Dulbecco'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 26:381-392
Slices of an interstitial cell tumor of the testis removed from a -yr-old boy were incubated with acetate-1-14C. Labeled androst-4-ene-3,17-dione, 11β-hydroxyandrost-4-ene-3,17-dione, androst-4-ene-3,11,17-trione, 3β-hydroxypregn-5-en-20-one, 17-hy
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 28:983-991
The metabolism of pregnenolone-7α-3H has been studied in vitro in an aldosterone producing tumor and in the adrenal tissue adjacent to the tumor. The predominant products in the incubation of the tumor tissue were progesterone, and lesser amounts of
Publikováno v:
Endocrinology. 69:354-372
Slices and homogenates of human fetal adrenals incubated with progesterone-4-C14 were shown to possess the enzymes necessary for converting this to deoxycorticosterone, 17-hydroxyprogesterone, and 16±-hydroxyprogesterone. The amount of product forme
Autor:
Dorothy B. Villee, John D. Crawford, Margaret H. MacGillivray, Robert E. Scully, Bernard Kliman
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 25:506-513
Testicular tissue removed from a 15½-yr-old boy with delayed sexual maturation, despite normal levels of urinary gonadotropins for 2 yr, was shown to be capable of converting pregnenolone-7α-3H to androstenedione, testosterone, 17-hydroxyprogestero
Autor:
Dorothy B. Villee
Publikováno v:
Clinical Pharmacology & Therapeutics. 14:705-713
Publikováno v:
Pediatrics. 43:207-216
Two boys with classical progeria have been studied by a variety of laboratories in the Boston area. Evidence for unresponsiveness to growth hormone, relative insulin resistance, and highly cross-linked collagen is presented. The data support the conc