Výsledky vyhledávání - "Dorothy A. Kozlowski"

Akademický článek

Sustained Hippocampal Synaptic Pathophysiology Following Single and Repeated Closed-Head Concussive Impacts

Autor: John McDaid, Clark A. Briggs, Nikki M. Barrington, Daniel A. Peterson, Dorothy A. Kozlowski, Grace E. Stutzmann

Publikováno v: Frontiers in Cellular Neuroscience, Vol 15 (2021)

Traumatic brain injury (TBI), and related diseases such as chronic traumatic encephalopathy (CTE) and Alzheimer’s (AD), are of increasing concern in part due to enhanced awareness of their long-term neurological effects on memory and behavior. Repe

Externí odkaz: https://doaj.org/article/76fabb92f95e479bb26c81e0fe077126

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Assessment of the Effects of Altered Amyloid-Beta Clearance on Behavior following Repeat Closed-Head Brain Injury in Amyloid-Beta Precursor Protein Humanized Mice

Autor: Robert A. Marr, Steven A. Miller, Dorothy A. Kozlowski, Trevor J. Buhr, Kathleen C. Maigler, Christopher S. Park

Publikováno v: J Neurotrauma

Traumatic brain injury (TBI) increases the risk for dementias including Alzheimer's disease (AD) and chronic traumatic encephalopathy. Further, both human and animal model data indicate that amyloid-beta (Aβ) peptide accumulation and its production

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b48d0f3ad92f08f5b078c6eb51ee0a
https://doi.org/10.1089/neu.2020.6989

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Targeted Gene Inactivation of Calpain-1 Suppresses Cortical Degeneration Due to Traumatic Brain Injury and Neuronal Apoptosis Induced by Oxidative Stress*

Autor: Shafi M. Kuchay, Ira M. Herman, Premanand Sundivakkam, Stacey E. Seidl, Chinnaswamy Tiruppathi, Kaori H. Yamada, Imran Chishti, Dorothy A. Kozlowski, Steven Lance, Adam J. Wieschhaus, Athar H. Chishti

Calpains are calcium-regulated cysteine proteases that have been implicated in the regulation of cell death pathways. Here, we used our calpain-1 null mouse model to evaluate the function of calpain-1 in neural degeneration following a rodent model o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f527866c0a5df429166059587554c36

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Repeat subconcussion in the adult rat gives rise to behavioral deficits similar to a single concussion but different depending upon sex

Autor: Rebecca J, Wilson, Margaret R, Bell, Katherine R, Giordano, Serena, Seyburn, Dorothy A, Kozlowski

Publikováno v: Behavioural Brain Research. 438:114206

Although concussions are a popular focus of neurotrauma research, subconcussions occur with higher frequency but are less well-studied. A subconcussion is an impact to the head that does not result in immediately diagnosable concussion but can result

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c26711c748db444327f59264aaab3b0
https://doi.org/10.1016/j.bbr.2022.114206

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Testosterone treatment restores vestibular function by enhancing neuronal survival in an experimental closed-head repetitive mild traumatic brain injury model

Autor: Eileen M, Foecking, Arthur B, Segismundo, Krista M, Lotesto, Edward J, Westfall, Alyssa J, Bolduan, Tony K, Peter, Douglas G, Wallace, Dorothy A, Kozlowski, Evan B, Stubbs, Sam J, Marzo, Susanna C, Byram

Publikováno v: Behavioural Brain Research. 433:113998

Repetitive mild traumatic brain injury (rmTBI) results in a myriad of symptoms, including vestibular impairment. The mechanisms underlying vestibular dysfunction in rmTBI patients remain poorly understood. Concomitantly, acute hypogonadism occurs fol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f3bd21f960b77a0e078489e4c707c4
https://doi.org/10.1016/j.bbr.2022.113998

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Traumatic Brain Injury in Victims of Domestic Violence

Autor: Sonya Crabtree-Nelson, Dorothy A. Kozlowski, Jonathan Lifshitz

Publikováno v: Journal of Aggression, Maltreatment & Trauma. 28:655-659

The article serves as the introduction to a special issue of the journal focused on traumatic brain injury in the context of domestic and intimate partner violence. The scope of the problem...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::83bd4460a5373fa1f39760437ea6c43b
https://doi.org/10.1080/10926771.2019.1644693

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A Clinically Relevant Closed-Head Model of Single and Repeat Concussive Injury in the Adult Rat Using a Controlled Cortical Impact Device

Autor: Janice H. Urban, Naseem Jamnia, Robert A. Marr, Emily K. Reisenbigler, Dorothy A. Kozlowski, Daniel A. Peterson, Grace E. Stutzmann, Sarah G Chiren

Publikováno v: Journal of Neurotrauma. 34:1351-1363

Repeat concussions (RC) can result in significant long-term neurological consequences and increased risk for neurodegenerative disease compared with single concussion (SC). Mechanisms underlying this difference are poorly understood and best elucidat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71455f0ccfb7e78577d1fe48d6cb9eab
https://doi.org/10.1089/neu.2016.4517

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Combinatorial Motor Training Results in Functional Reorganization of Remaining Motor Cortex after Controlled Cortical Impact in Rats

Autor: DeAnna L. Adkins, Theresa A. Jones, Hannah L Combs, Dorothy A. Kozlowski

Publikováno v: Journal of Neurotrauma. 33:741-747

Cortical reorganization subsequent to post-stroke motor rehabilitative training (RT) has been extensively examined in animal models and humans. However, similar studies focused on the effects of motor training after traumatic brain injury (TBI) are l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8817c936fad39dbd371c58c5fe49448
https://doi.org/10.1089/neu.2015.4136

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