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Autor:
Dorothy A. Beli, S. Bano Chishti, Erdjan Salih, Sachiko I. Howard, Saul G. Cohen, Jonathan B. Cohen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1076:112-122
To assess the relative importance of binding to enzyme-substrate complex (E.S) and to acetylenzyme (EA), noncompetitive inhibition has been studied in hydrolysis by acetylcholinesterase (AcChE) of cationic and uncharged substrates - acetylcholine (Ac