Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Dorothy A Thompson"'
Autor:
Mikhail Kulyabin, Paul A. Constable, Aleksei Zhdanov, Irene O. Lee, Dorothy A. Thompson, Andreas Maier
Publikováno v:
IEEE Access, Vol 12, Pp 52352-52362 (2024)
The electroretinogram (ERG) is a clinical test that records the retina’s electrical response to a brief flash of light as a waveform signal. Analysis of the ERG signal offers a promising non-invasive method for studying different neurodevelopmental
Externí odkaz:
https://doaj.org/article/44521ebdae604c5688d995fedecd9eed
Autor:
Mei Hong Tan, Donna S Mackay, Jill Cowing, Hoai Viet Tran, Alexander J Smith, Genevieve A Wright, Arundhati Dev-Borman, Robert H Henderson, Phillip Moradi, Isabelle Russell-Eggitt, Robert E MacLaren, Anthony G Robson, Michael E Cheetham, Dorothy A Thompson, Andrew R Webster, Michel Michaelides, Robin R Ali, Anthony T Moore
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32330 (2012)
Leber Congenital Amaurosis (LCA) and Early Childhood Onset Severe Retinal Dystrophy are clinically and genetically heterogeneous retinal disorders characterised by visual impairment and nystagmus from birth or early infancy. We investigated the preva
Externí odkaz:
https://doaj.org/article/ab358eecd7e74aa495b458512900acef
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract Objectives The electroretinogram is a clinical test commonly used in the diagnosis of retinal disorders with the peak time and amplitude of the a- and b-waves used as the main indicators of retinal function. However, subtle changes that affe
Externí odkaz:
https://doaj.org/article/bb185456b198479e8ceee07586b4eb5b
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
The retina and brain share similar neurochemistry and neurodevelopmental origins, with the retina, often viewed as a “window to the brain.” With retinal measures of structure and function becoming easier to obtain in clinical populations there is
Externí odkaz:
https://doaj.org/article/4f44d9d2d9df41029a7cb8827aacbc71
Autor:
Megan D. Kelley, Dorothy A. Thompson‐Butler, Matthew C. Tanner, Justin D. Thomason, William H. Whitehouse
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 6, Pp 2098-2103 (2022)
Abstract Background Acute kidney injury (AKI) in dogs has a high case fatality rate. Diltiazem might improve renal function, but effect of intravenous infusion has not been adequately studied in dogs. Hypothesis/Objectives To determine if an intraven
Externí odkaz:
https://doaj.org/article/e8e588dae08d4b22b0239fa50f89cce9
Autor:
Haiyan Zhou, Ying Hong, Mariacristina Scoto, Alison Thomson, Emma Pead, Tom MacGillivray, Elena Hernandez-Gerez, Francesco Catapano, Jinhong Meng, Qiang Zhang, Gillian Hunter, Hannah K. Shorrock, Thomas K. Ng, Abedallah Hamida, Mathilde Sanson, Giovanni Baranello, Kevin Howell, Thomas H. Gillingwater, Paul Brogan, Dorothy A. Thompson, Simon H. Parson, Francesco Muntoni
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 21 (2022)
Spinal muscular atrophy (SMA) is a neuromuscular disorder due to degeneration of spinal cord motor neurons caused by deficiency of the ubiquitously expressed SMN protein. Here, we present a retinal vascular defect in patients, recapitulated in SMA tr
Externí odkaz:
https://doaj.org/article/7bf2c0654d0b499f9112525f28926aef
Autor:
Paul A. Constable, Fernando Marmolejo-Ramos, Mercedes Gauthier, Irene O. Lee, David H. Skuse, Dorothy A. Thompson
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
BackgroundTo evaluate the electroretinogram waveform in autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) using a discrete wavelet transform (DWT) approach.MethodsA total of 55 ASD, 15 ADHD and 156 control individuals
Externí odkaz:
https://doaj.org/article/1c19f6f3a5bc48659982d98b4b8f3be8
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Introduction Raised intracranial pressure (rICP) can be a consequence of a variety of neurological disorders. A significant complication of rICP is visual impairment, due to retinal ganglion cell (RGC) dysfunction. In children, subjective measurement
Externí odkaz:
https://doaj.org/article/938981fb7665471c9c8152aad23ce38f
Publikováno v:
The Journal of Physiology. 601:1869-1880
Publikováno v:
Documenta Ophthalmologica. 146:181-189
Purpose To report an unexpectedly asymmetric, progressive nutritional optic neuropathy associated with vitamin A deficient optic canal hyperostosis in a 15-year-old female with a long history of a restricted diet. Methods We performed comprehensive o