Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Dorothee von‐Laer"'
Autor:
Laura Krismer, Helge Schöppe, Stefanie Rauch, David Bante, Bernhard Sprenger, Andreas Naschberger, Francesco Costacurta, Anna Fürst, Anna Sauerwein, Bernhard Rupp, Teresa Kaserer, Dorothee von Laer, Emmanuel Heilmann
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-20 (2024)
Abstract The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an epidemic, zoonotically emerging pathogen initially reported in Saudi Arabia in 2012. MERS-CoV has the potential to mutate or recombine with other coronaviruses, thus acquiring
Externí odkaz:
https://doaj.org/article/1322a7caaeab4ab2b156087e0d939fa6
Autor:
Francesco Costacurta, Andrea Dodaro, David Bante, Helge Schöppe, Ju-Yi Peng, Bernhard Sprenger, Xi He, Seyed Arad Moghadasi, Lisa Maria Egger, Jakob Fleischmann, Matteo Pavan, Davide Bassani, Silvia Menin, Stefanie Rauch, Laura Krismer, Anna Sauerwein, Anne Heberle, Toni Rabensteiner, Joses Ho, Reuben S Harris, Eduard Stefan, Rainer Schneider, Theresia Dunzendorfer-Matt, Andreas Naschberger, Dai Wang, Teresa Kaserer, Stefano Moro, Dorothee von Laer, Emmanuel Heilmann
Publikováno v:
PLoS Pathogens, Vol 20, Iss 9, p e1012522 (2024)
Nirmatrelvir was the first protease inhibitor specifically developed against the SARS-CoV-2 main protease (3CLpro/Mpro) and licensed for clinical use. As SARS-CoV-2 continues to spread, variants resistant to nirmatrelvir and other currently available
Externí odkaz:
https://doaj.org/article/8a2d120a7782489fb1d69e04556b8418
Autor:
Wegene Borena, Maria Kitchen, Martin Gisinger, Ninon Taylor, Hannes Oberkofler, Diyani Dewasurendra, Andreas Widschwendter, Heribert Stoiber, Dorothee von Laer, Mario Sarcletti
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundIn this study, we characterized the HPV genotype distribution in a population of 489 adults already positive for HPV DNA. The study population was divided into two groups: 244 HIV-positive (HIV+) men who have sex with men (MSM) undergoing r
Externí odkaz:
https://doaj.org/article/065f0695f7ff4856927bd4b478969001
Autor:
Annika Rössler, Antonia Netzl, Ludwig Knabl, Samuel H. Wilks, Barbara Mühlemann, Sina Türeli, Anna Mykytyn, Dorothee von Laer, Bart L. Haagmans, Derek J. Smith, Janine Kimpel
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-4 (2024)
Abstract Antigenic characterization of newly emerging SARS-CoV-2 variants is important to assess their immune escape and judge the need for future vaccine updates. To bridge data obtained from animal sera with human sera, we analyzed neutralizing ant
Externí odkaz:
https://doaj.org/article/1b378345d91f470881a83e3cee0c454e
Autor:
Janine Kimpel, Annika Rössler, David Bante, Wegene Borena, Dorothee von Laer, Claus Zehetner, Teresa Rauchegger, Stefanie Seiwald, Barbara Falkensammer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionSARS-CoV-2 is known to infect respiratory tissue cells. However, less is known about infection of ocular tissue and potential infectivity of lacrimal fluid. With this study, we want to compare viral loads in eye and nasopharyngeal swabs a
Externí odkaz:
https://doaj.org/article/0c60f59067ae49278d2990d0e5764ab1
Autor:
Lea Maria Schuler, Barbara Falkensammer, Peter Orlik, Michael Auckenthaler, Christof Kranewitter, David Bante, Dorothee von Laer, Franz-Martin Fink
Publikováno v:
Microorganisms, Vol 12, Iss 7, p 1377 (2024)
The clinical presentation, organ involvement, and severity of disease caused by SARS-CoV-2 are highly variable, ranging from asymptomatic or mild infection to respiratory or multi-organ failure and, in children and young adults, the life-threatening
Externí odkaz:
https://doaj.org/article/1fb870771f1e48d2ac8bde14fcb58f51
Autor:
Annika Rössler, Antonia Netzl, Ludwig Knabl, David Bante, Samuel H. Wilks, Wegene Borena, Dorothee von Laer, Derek J. Smith, Janine Kimpel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Since emergence of the initial SARS-CoV-2 BA.1, BA.2 and BA.5 variants, Omicron has diversified substantially. Antigenic characterization of these new variants is important to analyze their potential immune escape from population immunity an
Externí odkaz:
https://doaj.org/article/82cc591f90aa4f0e86ebfe4eec338390
Autor:
Christoph Schatz, Ludwig Knabl, Hye Kyung Lee, Rita Seeboeck, Dorothee von Laer, Eliott Lafon, Wegene Borena, Harald Mangge, Florian Prüller, Adelina Qerimi, Doris Wilflingseder, Wilfried Posch, Johannes Haybaeck
Publikováno v:
Microorganisms, Vol 12, Iss 4, p 798 (2024)
The global dissemination of SARS-CoV-2 resulted in the emergence of several variants, including Alpha, Alpha + E484K, Beta, and Omicron. Our research integrated the study of eukaryotic translation factors and fundamental components in general protein
Externí odkaz:
https://doaj.org/article/ec94e45b9b714244ab8eaaa2f136e70e
Autor:
Beatriz Perdiguero, Alexandra Hauser, Carmen Elena Gómez, David Peterhoff, Elefthéria Sideris, Carlos Óscar S. Sorzano, Sarah Wilmschen, Marion Schaber, Laura Stengel, Benedikt Asbach, Song Ding, Dorothee Von Laer, Yves Levy, Giuseppe Pantaleo, Janine Kimpel, Mariano Esteban, Ralf Wagner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe generation of an HIV-1 vaccine able to induce long-lasting protective immunity remains a main challenge. Here, we aimed to modify next-generation soluble, prefusion-stabilized, close-to-native, glycan-engineered clade C gp140 envelope
Externí odkaz:
https://doaj.org/article/8678f1d6bd254349ba452be5f5fce815
Autor:
Annika Rössler, Antonia Netzl, Ludwig Knabl, Helena Schäfer, Samuel H. Wilks, David Bante, Barbara Falkensammer, Wegene Borena, Dorothee von Laer, Derek J. Smith, Janine Kimpel
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
SARS-CoV-2 omicron variant BA.1 has shown increased transmissibility and immune escape, relative to previous SARS-CoV-2 variants. In this study, authors utilise antigenic cartography to characterise the neutralisation profiles of omicron sub-lineages
Externí odkaz:
https://doaj.org/article/711c1bed57254d67954fe9568b0ff4e9